Genes Phenotypes

Gene: Mks1

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Name
Meckel syndrome, type 1
MGI ID
MGI:3584243
Synonyms
B8d3 avc6
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (141) All data table (243)
Expression & images (45) Disease models (0) Order (1)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal nail morphology Mks1tm1a(EUCOMM)Wtsi HET Early adult 3.63×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (1/2) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Mks1tm1a(EUCOMM)Wtsi
trachea, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
oviduct, HET, Female, WTSI

View all 8 images

Mks1tm1a(EUCOMM)Wtsi
trachea, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
oviduct, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
peripheral nervous system, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
oviduct, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
trachea, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
lymph node, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
cartilage tissue, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Mks1tm1a(EUCOMM)Wtsi
head, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
head, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
head, HET, Male, WTSI
Mks1tm1a(EUCOMM)Wtsi
head, HET, Female, WTSI

View all 154 images

Mks1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Mks1tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

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MGI Allele Allele Type Produced
Mks1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells