Gene: Dok7

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount Dok7tm1.1(KOMP)Vlcg HET postnatal 2.36×10-05
decreased threshold for auditory brainstem response Dok7tm1.1(KOMP)Vlcg HET postnatal 7.11×10-05
decreased lean body mass Dok7tm1.1(KOMP)Vlcg HET postnatal 1.05×10-05
preweaning lethality, complete penetrance Dok7tm1.1(KOMP)Vlcg HOM n/a 0.00
increased bone mineral density Dok7tm1.1(KOMP)Vlcg HET postnatal 6.34×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (2/2)  Section images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
10 Images
X-ray: XRay Images Lateral Orientation
13 Images
X-ray: XRay Images Dorso Ventral
7 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Dok7tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Dok7tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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