Mfsd2b | MFSD2 lysolipid transporter B, sphingolipid

GeneMGI:3583946Synonyms: Gm1964, major facilitator superfamily domain containing 2B

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Hematopoietic system

16 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

decreased circulating iron level1 supporting datasetMfsd2btm1a(KOMP)WtsihomozygoteEarly adult1.27x10-7 
decreased erythrocyte cell number1 supporting datasetMfsd2btm1a(KOMP)WtsihomozygoteEarly adult3.46x10-5 
increased mean corpuscular hemoglobin1 supporting datasetMfsd2btm1a(KOMP)WtsihomozygoteEarly adult4.7x10-5 
increased body length1 supporting datasetMfsd2btm1a(KOMP)WtsihomozygoteEarly adult2.2x10-5 
abnormal vibrissa morphology1 supporting datasetMfsd2btm1a(KOMP)WtsihomozygoteEarly adult1.57x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mfsd2btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mfsd2btm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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