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Gene: Elmod1

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Name
ELMO/CED-12 domain containing 1
MGI ID
MGI:3583900
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (52) Measurements chart (299) All data table (809)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.22×10-07
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.63×10-20
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.03×10-09
increased heart weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 8.03×10-06
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.07×10-09
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.25×10-10
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 8.19×10-41
decreased thigmotaxis Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.17×10-23
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.34×10-10
increased heart rate variability Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 5.26×10-05
abnormal startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.14×10-18
tremors Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.28×10-09
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.30×10-15
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.29×10-13
decreased B cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 8.62×10-10
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.85×10-10
increased kidney weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.16×10-10
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 3.45×10-07
abnormal auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 1.24×10-06
decreased grip strength Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.40×10-05
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.94×10-20
shortened PQ interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.40×10-05
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 2.28×10-07
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.53×10-07
trunk curl Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 5.42×10-06
decreased prepulse inhibition Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 2.46×10-07
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.98×10-06
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.43×10-06
decreased monocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.98×10-09
decreased circulating cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 1.45×10-05
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.86×10-05
decreased circulating glucose level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 7.45×10-05
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.25×10-06
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.98×10-19
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.91×10-06
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.68×10-27
decreased anxiety-related response Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.10×10-09
decreased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.35×10-05
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.89×10-18
thrombocytopenia Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.29×10-07
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.40×10-07
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.21×10-10
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.49×10-22
decreased large unstained cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.14×10-05
decreased circulating HDL cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 3.42×10-08
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.01×10-18
shortened PR interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.96×10-06
decreased circulating HDL cholesterol level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.40×10-05
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.92×10-13
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.75×10-09
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.12×10-23
hypoactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.36×10-14

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (2/2)  Wholemount images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
integumental system (1)
Skin expression
MA:0000151
nervous system (6)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0002413
MA:0000185
MA:0000173
postnatal mouse (9)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0002413
MA:0000185
MA:0000173
reproductive system (2)
Oviduct expression
MA:0000385
trunk (4)
Oviduct expression
MA:0000385
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/5) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (3/5) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506)  (2/5) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/506) N/A
Head 2  (5/506)  (3/5) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

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Adult LacZ: LacZ Images Wholemount
9 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
thumbnail
Echo: M-Mode Images
17 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
thumbnail
X-ray: XRay Images Hind Leg and Hip
8 Images
thumbnail
Embryo LacZ: LacZ images wholemount
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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