Genes Phenotypes

Gene: Elmod1

Name
ELMO/CED-12 domain containing 1
MGI ID
MGI:3583900
Synonyms
N/A
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (51) Measurements chart (556) All data table (1289)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 2.85×10-10
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 1.43×10-08
decreased bone mineral density Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.95×10-05
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 3.37×10-20
increased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 6.94×10-05
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.58×10-07
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 3.61×10-16
increased blood urea nitrogen level Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 4.10×10-08
tremors Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 9.24×10-05
decreased bone mineral content Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.09×10-07
decreased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 6.94×10-05
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 1.98×10-19
increased or absent threshold for auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.00×10-06
increased heart weight Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.28×10-05
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 4.47×10-07
mammalian phenotype Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 8.52×10-05
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.44×10-17
absent startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.33×10-16
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.07×10-06
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.66×10-05
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 4.14×10-16
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 2.41×10-12
increased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 8.92×10-06
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 5.34×10-11
abnormal bone structure Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 6.19×10-07
decreased body weight Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 2.98×10-26
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.08×10-16
decreased spleen weight Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 9.54×10-05
decreased grip strength Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 5.12×10-10
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.89×10-05
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 8.22×10-19
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.12×10-07
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 3.16×10-16
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 5.98×10-06
thrombocytopenia Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 9.61×10-06
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.50×10-17
decreased prepulse inhibition Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 7.58×10-08
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 4.76×10-07
tremors Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 2.28×10-09
decreased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 6.45×10-07
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.90×10-09
abnormal iris morphology Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 8.86×10-05
decreased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 8.92×10-06
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 3.24×10-06
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 1.67×10-33
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 2.25×10-10
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.37×10-10
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 2.83×10-13
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 1.26×10-19
decreased monocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM postnatal 4.29×10-07
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM postnatal 1.22×10-07

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
nervous system (5)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000168
MA:0000185
MA:0000191
MA:0000173
MA:0002413
MA:0000891
postnatal mouse (6)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Hypothalamus expression
Olfactory Lobe expression
Striatum expression
MA:0000168
MA:0000185
MA:0000191
MA:0000173
MA:0002413
MA:0000891
reproductive system (1)
Testis expression
MA:0000411
trunk (2)
Spinal cord expression
MA:0000216
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/5) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (3/5) N/A
Eye 2  (1/485) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (2/5) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (3/5) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
17 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Adult LacZ: LacZ Images Wholemount
6 Images
X-ray: XRay Images Dorso Ventral
17 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
2 Images
X-ray: XRay Images Hind Leg and Hip
8 Images
Echo: M-Mode Images
17 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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