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Gene: Elmod1

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Name
ELMO/CED-12 domain containing 1
MGI ID
MGI:3583900
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (51) Measurements chart (272) All data table (795)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating HDL cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 2.63×10-07
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.11×10-15
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.63×10-06
tremors Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 7.20×10-05
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.95×10-07
increased circulating phosphate level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.20×10-06
decreased circulating glycerol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 7.73×10-05
increased blood urea nitrogen level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.76×10-07
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.98×10-19
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.85×10-10
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.71×10-05
increased heart rate variability Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.66×10-15
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.81×10-10
shortened PR interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.28×10-08
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.22×10-22
decreased large unstained cell number Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 5.93×10-05
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 8.54×10-20
decreased circulating cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 9.48×10-06
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
shortened PQ interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.77×10-07
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.77×10-06
decreased anxiety-related response Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.38×10-44
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.30×10-07
increased kidney weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.22×10-06
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.44×10-07
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.56×10-06
abnormal auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 1.24×10-06
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.30×10-20
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.96×10-07
trunk curl Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 5.42×10-06
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.04×10-20
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.78×10-13
tremors Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.28×10-09
abnormal startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.05×10-18
cardiovascular system phenotype Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 8.42×10-09
decreased B cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 9.72×10-06
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 8.19×10-41
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.25×10-10
increased eosinophil cell number Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 2.08×10-05
decreased thigmotaxis Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.98×10-06
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.99×10-18
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.54×10-08
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.22×10-07
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 0.00
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.45×10-05
decreased monocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.74×10-09
hypoactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.76×10-41
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.56×10-06
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.92×10-13
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.68×10-08

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (4/584)  (2/2)  Wholemount images
2 No  (2/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (3/584) N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No  (7/408) N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (2/584)  (2/2)  Wholemount images
2 No  (21/584) N/A
2 No  (10/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (2/584)  (2/2)  Wholemount images
2 No N/A
2 No  (1/584) N/A
2 No  (1/2)  Wholemount images
2 No  (5/584) N/A
2 No  (1/562) N/A
2 No  (2/584) N/A
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (12/584) N/A
2 No N/A
2 No  (1/584)  (2/2)  Wholemount images
2 No  (9/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (3/584) N/A
2 No  (12/584) N/A
2 No  (3/584)  (2/2)  Wholemount images
2 No  (6/584)  (1/2)  Wholemount images
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (3/584) N/A
2 No N/A
2 No N/A
2 No N/A
LacZ Wholemount Images
integumental system (1)
Skin expression
MA:0000151
nervous system (6)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
postnatal mouse (9)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
reproductive system (2)
Oviduct expression
MA:0000385
trunk (4)
Oviduct expression
MA:0000385
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/507)  (2/5) N/A
Ear 2  (1/507) N/A
Embryo 2  (1/508)  (3/5) N/A
Eye 2  (1/507) N/A
Footplate 2  (1/507) N/A
Forebrain 2  (1/507)  (2/5) N/A
Forelimb 2  (1/507) N/A
Handplate 2  (1/507) N/A
Head 2  (5/507)  (3/5) N/A
Heart 2  (1/507) N/A
Hindbrain 2  (6/507) N/A
Hindlimb 2  (1/507) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/507) N/A
Maxillary process 2  (1/507) N/A
Midbrain 2  (1/507) N/A
Oral cavity 2  (1/502) N/A
Skin 2  (1/507) N/A
Tail 2  (1/507) N/A
Tail somite group 2  (1/507) N/A

 Associated Images

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Embryo LacZ: LacZ images wholemount
10 Images
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Adult LacZ: LacZ Images Wholemount
9 Images
thumbnail
X-ray: XRay Images Hind Leg and Hip
8 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
thumbnail
Echo: M-Mode Images
17 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice