Gene: Elmod1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
tremors Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.28×10-09
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.41×10-12
trunk curl Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.42×10-06
decreased grip strength Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.12×10-10
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.74×10-13
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.85×10-07
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.72×10-05
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.28×10-21
mammalian phenotype Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 8.52×10-05
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.22×10-07
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.82×10-20
decreased monocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.54×10-07
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.39×10-22
increased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 6.94×10-05
increased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.72×10-06
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.07×10-06
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.98×10-06
decreased prepulse inhibition Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 7.58×10-08
decreased bone mineral density Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.12×10-05
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.59×10-07
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.05×10-05
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.25×10-10
abnormal iris morphology Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.57×10-05
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.64×10-07
increased blood urea nitrogen level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.10×10-08
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 3.24×10-06
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.28×10-09
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.88×10-15
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.43×10-08
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.85×10-10
decreased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.21×10-07
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.40×10-23
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.76×10-07
abnormal bone structure Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.86×10-07
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 8.22×10-19
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.48×10-18
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.18×10-11
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.98×10-19
increased heart weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.28×10-05
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.67×10-19
decreased bone mineral content Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.26×10-07
thrombocytopenia Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.13×10-06
decreased hemoglobin content Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 6.94×10-05
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.44×10-17
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.66×10-16
decreased spleen weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.54×10-05
increased or absent threshold for auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.00×10-06
abnormal startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.50×10-18
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.67×10-33
decreased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.72×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/5) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (3/5) N/A
Eye 2  (1/504) N/A
Foot 2  (1/504) N/A
Forebrain 2  (1/504)  (2/5) N/A
Forelimb 2  (1/504) N/A
Hand 2  (1/503) N/A
Head 2  (5/504)  (3/5) N/A
Heart 2  (1/504) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
6 Images
Embryo LacZ: LacZ images wholemount
10 Images
Echo: M-Mode Images
17 Images
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
X-ray: XRay Images Hind Leg and Hip
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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