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Gene: Elmod1

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Name
ELMO/CED-12 domain containing 1
MGI ID
MGI:3583900
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (56) Measurements chart (280) All data table (809)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased thigmotaxis Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.26×10-21
abnormal startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.14×10-18
trunk curl Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 5.42×10-06
decreased B cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 9.72×10-06
tremors Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.28×10-09
increased circulating alkaline phosphatase level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.29×10-13
increased startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 8.19×10-41
decreased prepulse inhibition Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 3.41×10-07
abnormal auditory brainstem response Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 1.24×10-06
increased mean platelet volume Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.00×10-05
increased mean corpuscular hemoglobin Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.87×10-07
shortened PQ interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 8.80×10-07
decreased leukocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.26×10-09
increased blood urea nitrogen level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 7.43×10-06
abnormal behavior Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.92×10-13
abnormal ear morphology Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.70×10-20
increased red blood cell distribution width Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.45×10-09
increased heart rate variability Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 4.40×10-05
increased circulating chloride level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 4.86×10-05
abnormal locomotor behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.07×10-19
decreased circulating triglyceride level Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.39×10-05
increased granulocyte number Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 5.96×10-06
increased mean corpuscular volume Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.78×10-07
decreased grip strength Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.40×10-05
thrombocytopenia Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 3.45×10-07
abnormal gait Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.85×10-10
increased heart weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.00×10-05
decreased grip strength Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.12×10-10
decreased startle reflex Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.51×10-23
abnormal startle reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.98×10-19
abnormal gait Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.16×10-18
thrombocytopenia Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.69×10-06
shortened PR interval Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.38×10-08
decreased circulating HDL cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 3.42×10-08
trunk curl Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.32×10-15
decreased anxiety-related response Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 9.86×10-09
hypoactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 3.07×10-13
decreased circulating glycerol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 2.51×10-05
tremors Elmod1tm1b(EUCOMM)Hmgu HOM   Early adult 7.69×10-05
increased blood urea nitrogen level Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 9.54×10-07
increased lean body mass Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.25×10-06
decreased total body fat amount Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.02×10-18
increased kidney weight Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.90×10-10
decreased prepulse inhibition Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 2.46×10-07
decreased large unstained cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 4.81×10-05
hyperactivity Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 6.76×10-11
decreased circulating cholesterol level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 1.45×10-05
head bobbing Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 1.53×10-22
abnormal behavior Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.16×10-23
decreased circulating glucose level Elmod1tm1a(EUCOMM)Hmgu HOM   Early adult 7.45×10-05
decreased lymphocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 5.37×10-10
decreased monocyte cell number Elmod1tm1b(EUCOMM)Hmgu HOM Early adult 2.74×10-09
abnormal locomotor activation Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 1.22×10-07
decreased leukocyte cell number Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.43×10-06
impaired pupillary reflex Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 2.25×10-10
abnormal response to tactile stimuli Elmod1tm1a(EUCOMM)Hmgu HOM Early adult 5.98×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (4/583)  (2/2)  Wholemount images
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No  (7/407) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (2/583)  (2/2)  Wholemount images
2 No  (21/583) N/A
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (2/583)  (2/2)  Wholemount images
2 No N/A
2 No  (1/583) N/A
2 No  (1/2)  Wholemount images
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583)  (2/2)  Wholemount images
2 No  (12/583) N/A
2 No N/A
2 No  (1/583)  (2/2)  Wholemount images
2 No  (9/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583)  (2/2)  Wholemount images
2 No  (6/583)  (1/2)  Wholemount images
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
LacZ Wholemount Images
integumental system (1)
Skin expression
MA:0000151
nervous system (6)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
postnatal mouse (9)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
reproductive system (2)
Oviduct expression
MA:0000385
trunk (4)
Oviduct expression
MA:0000385
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/5) N/A
2  (1/505) N/A
2  (1/506)  (3/5) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505)  (2/5) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (5/505)  (3/5) N/A
2  (1/505) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A

 Associated Images

thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
thumbnail
Embryo LacZ: LacZ images wholemount
10 Images
thumbnail
Echo: M-Mode Images
17 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
9 Images
thumbnail
X-ray: XRay Images Hind Leg and Hip
8 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
17 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Elmod1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Elmod1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice