Gene: Pram1

Name
PML-RAR alpha-regulated adaptor molecule 1
MGI ID
MGI:3576625
Synonyms
N/A
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Alanine aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.708 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Creatinine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0128 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Mean cell hemoglobin concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.508 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Radius HOM 4f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Fibula HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Mean platelet volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.179 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.315 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Eosinophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.538 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Shape of vertebrae HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Brachydactyly HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Scapulae HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.122 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Zygomatic bone HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Calcium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.896 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Shape of ribs HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Hematocrit HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.225 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.128 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.581 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Creatine kinase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.955 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.352 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Potassium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.446 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.589 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Phosphorus HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0871 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 0.198 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Viability Primary Screen / Outcome HOM 79f:73m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.625 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Lymphocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.148 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.173 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0781 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Triglycerides HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.181 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Clavicle HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Platelet count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.466 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Digit integrity HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Total protein HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.613 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.743 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.181 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Fusion of vertebrae HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Tibia HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Aspartate aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.722 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Eosinophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.799 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0458 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0888 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0148 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Syndactylism HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.992 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.731 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Sodium HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Organ Weight / Heart weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0135 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.653 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Neutrophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.313 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / HDL-cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.772 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.180 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.403 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.340 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0405 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Processes on vertebrae HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Lymphocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.530 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Monocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0271 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0375 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Number of ribs right HOM 4f:6m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0360 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.0722 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Alpha-amylase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.405 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Iron HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.426 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 0.170 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.967 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.310 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Albumin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.183 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.575 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0458 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Pelvis HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.548 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Mean cell volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0473 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Femur HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.315 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Basophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0722 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.173 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Red blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0664 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.700 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.503 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Organ Weight / Right kidney HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0781 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Mandibles HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Neutrophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.847 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Humerus HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Number of digits HOM 4f:6m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0355 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0252 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Ulna HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Organ Weight / Spleen weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0871 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Fructosamine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.441 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Alkaline phosphatase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.740 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Monocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0252 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Teeth HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.395 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Number of ribs left HOM 4f:6m 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.548 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Mean corpuscular hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.816 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.754 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.875 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Total bilirubin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.780 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Fusion of ribs HOM 4f:6m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.686 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Basophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.598 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Center resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.961 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.472 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Joints HOM 4f:6m Fisher Exact Test framework 0.0125 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Skull shape HOM 4f:6m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / Red blood cell distribution width HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.127 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Clinical Chemistry / Chloride HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0478 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell X-ray / Tibia length HOM 4f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.570 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.664 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 0.00644 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0358 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Organ Weight / Left kidney HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.481 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Hematology / White blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.183 Success
Pram1tm1b(EUCOMM)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  Wholemount images
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (1/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
6 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pram1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Pram1tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pram1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Pram1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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