Gramd2a | GRAM domain containing 2A
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Skeleton Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged urinary bladder | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| abnormal pancreas morphology | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| vertebral fusion | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Early adult | 6.14x10-5 | ||
| abnormal liver morphology | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Late adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| small uterus | 1 supporting dataset | Gramd2aem1(IMPC)Tcp | homozygote | Late adult | N/A * |
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Human diseases caused by Gramd2a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Gramd2a.
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| Gramd2aem1(IMPC)Tcp | Exon Deletion | | mouse |
| Gramd2atm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Gramd2atm79352(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |