Gene Summary
IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Nt5dc3 by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
3-Hydroxy-3-Methylglutaryl-Coa Synthase Deficiency | Hypoglycemia | ORPHA:35701 | |
Glucocorticoid Deficiency 3 | Recurrent hypoglycemia | OMIM:609197 | |
Hyperinsulinemic Hypoglycemia, Familial, 7 | Hyperinsulinemia, Hypoglycemia, Hypoglycemic seizures, Hyperinsulinemic hypoglycemia | OMIM:610021 | |
Maturity-Onset Diabetes Of The Young, Type 3 | Hyperglycemia, Type II diabetes mellitus, Maturity-onset diabetes of the young | OMIM:600496 | |
Glycogen Storage Disease 0, Liver | Postprandial hyperglycemia, Neonatal hypoglycemia, Fasting hypoglycemia | OMIM:240600 | |
Hyperproinsulinemia | Hyperglycemia, Hyperinsulinemia | OMIM:616214 | |
Hyperinsulinism Due To Insr Deficiency | Hypoglycemia, Insulin resistance, Fasting hyperinsulinemia, Recurrent hypoglycemia, Hyperinsuline... | ORPHA:263458 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Nt5dc3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
Nt5dc3em1(IMPC)J | Exon Deletion | Mice |
Nt5dc3tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Nt5dc3tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Nt5dc3tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Nt5dc3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Get highlights of the most important data releases, news and events, delivered straight to your email inbox
Subscribe to newsletter