Genes Phenotypes

Gene: Cbx6

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Name
chromobox 6
MGI ID
MGI:3512628
Synonyms
N/A
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (18) Measurements chart (386) All data table (511)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased CD8-positive, alpha-beta T cell number Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 3.47×10-05
decreased circulating insulin level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.17×10-11
decreased T cell number Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 8.13×10-05
increased lean body mass Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 5.50×10-09
increased bone mineral content Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 5.92×10-09
decreased total body fat amount Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 6.55×10-12
increased circulating sodium level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 2.99×10-17
decreased circulating glucose level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.68×10-08
increased circulating creatinine level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.42×10-06
increased circulating chloride level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.32×10-08
decreased circulating cholesterol level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 2.79×10-07
abnormal bone structure Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 3.64×10-05
decreased caudal vertebrae number Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 0.00
decreased lean body mass Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.12×10-10
abnormal tibia morphology Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.31×10-06
decreased circulating magnesium level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.11×10-05
decreased circulating HDL cholesterol level Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 3.65×10-08
decreased body weight Cbx6tm1a(EUCOMM)Wtsi HOM Early adult 1.65×10-09

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Brain Histopathology: Hippocampal section
3 Images
Brain Histopathology: Striatal Section
1 Images
X-ray: XRay Images Whole Body Dorso Ventral
40 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Forepaw
12 Images
Legacy Phenotype Associated Images
Cbx6tm1a(EUCOMM)Wtsi
body, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
head, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
head, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
body, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
head, HOM, Male, WTSI

View all 128 images

Cbx6tm1a(EUCOMM)Wtsi
dentate gyrus, decreased dentate gyrus size, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
WT, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
corpus callosum, decreased corpus callosum size, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
decreased dentate gyrus size, dentate gyrus, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
anterior commissure, decreased anterior commissure size, HOM, Male, WTSI

View all 10 images

Cbx6tm1a(EUCOMM)Wtsi
persistence of hyaloid vascular system, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
abnormal retinal blood vessel pattern, HOM, Male, WTSI
Cbx6tm1a(EUCOMM)Wtsi
cornea/lens fusion, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
abnormal eyelid morphology, right eye, narrow eye opening, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
cornea/lens fusion, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
abnormal epidermal pigmentation, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
abnormal epidermal pigmentation, HOM, Female, WTSI
Cbx6tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cbx6tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Cbx6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cbx6tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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