Gene: Fbxl7

Name
F-box and leucine-rich repeat protein 7
MGI ID
MGI:3052506
Synonyms
D230018M15Rik FBL7 Fbl6
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (285) Expression & images (0) Disease models (0) Order (1)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.171 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.308 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of thoracic vertebrae HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000952 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Kyphosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Lumbar processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Thickness (mm) HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.706 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Radius HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Fibula HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Mean platelet volume HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.321 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Shape of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.765 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Brachydactyly HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Bone Mineral Density HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.143 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Scapulae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Monocyte percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.282 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / LDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0881 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Height HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.835 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / CD8+CD44+CD62L- percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.336 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Zygomatic bone HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00964 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Shape of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Polysyndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00639 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.514 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific total IgG HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Salmonella Challenge / Caecal Contents bacterial count HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0549 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Creatine kinase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.577 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail length HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Potassium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0827 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.429 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Phosphorus HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0436 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Three-point Bend / Stiffness HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.675 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Thyroxine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0101 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Viability Primary Screen / Outcome HOM 42f:44m Supplied as data Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Indirect Calorimetry / Total water intake HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withWeight 0.262 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head bobbing/circling HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail elevation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.877 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD8+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.862 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 0f:3m 0.565 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Triglycerides HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.180 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Clavicle HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Platelet count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.507 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Spacing (mm) HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0149 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / NK cell percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00333 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Digit integrity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Transfer arousal HOM 7f:7m Fisher Exact Test framework 0.215 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.285 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.418 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of cervical vertebrae HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Three-point Bend / Fracture Load HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.136 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Scoliosis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisor colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Granulocyte Gr1+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.492 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Tibia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Aspartate aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.999 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.326 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0462 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Syndactylism HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.180 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Sodium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.416 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Glycerol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0728 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.492 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD3+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.122 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Femoral Microradiography / Femur Length HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.530 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.377 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Corneal touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Contact righting reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00907 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw footpad size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Cervical processes HOM 7f:7m Fisher Exact Test framework 0.539 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Yield Load HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.820 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Maxilla/Pre-maxilla HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Salmonella Challenge / Spleen bacterial count HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Three-point Bend / Yield Load HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0546 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Gait (inc. ataxia) HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Caudal processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindlimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Cortical Thickness HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0396 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.269 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / NKT cell percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0507 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of ribs right HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alpha-amylase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.130 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / Click-evoked ABR threshold HOM 0f:3m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0731 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Magnesium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.427 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Convulsions HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00176 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.885 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.278 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG1 HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Salmonella Challenge / Pre-Day 14 Death HOM 2f:2m - 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit fusion HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Transitional vertebrae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Pelvis HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0999 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Three-point Bend / Energy Dissipated Prior to Fracture HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.224 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna rotation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Shape of spine HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Mean cell volume HOM 7f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_HEM_005_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Femur HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Femoral Microradiography / Femoral Bone Mineral Content HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.890 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Max Load HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.918 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 0.654 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Free fatty acids HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.828 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 0f:3m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.127 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0248 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / B cell CD19+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.595 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Positional passivity HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair colour pattern HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Mature B cell IgD+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.468 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw footpad skin colour HOM 7f:7m Fisher Exact Test framework 0.0482 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Trabecular Number (mm-1) HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0248 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / T cell CD4+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0591 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Vibrissae HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Mandibles HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Thoracic processes HOM 7f:7m Fisher Exact Test framework 0.386 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna touch reflex HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Humerus HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of digits HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.581 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Incisors HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of lumbar vertebrae HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Lordosis HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Ulna HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Sacral processes HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Vertebral Microradiography / Vertebral Bone Mineral Content HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0977 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Fructosamine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.899 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.110 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw digit count HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / External genitalia size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of caudal vertebrae HOM 7f:7m 0.590 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Teeth HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of ribs left HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Cortical Bone MicroCT / Internal Diameter HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.0550 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw nail colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / CD4+CD44+CD62L- percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0993 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Ventral coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.826 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 0.316 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Antigen Specific Immunoglobulin Assay / TetC specific IgG2 HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0141 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.375 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Total bilirubin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.101 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Limb grasping HOM 7f:7m Fisher Exact Test framework 0.0105 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tail skin colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of ribs HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.508 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Paw coat/hair presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Hindpaw digit size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Head coat/hair appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forepaw nail count HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Vertebra Compression / Vertebra Stiffness HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.950 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.493 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Joints HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Skull shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Pinna skin appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Fusion of processes HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / Red blood cell distribution width HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.659 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Forelimb HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Digit coat/hair colour HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Insulin Blood Level / Insulin HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00784 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Clinical Chemistry / Chloride HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0774 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.312 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 0.386 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Three-point Bend / Max Load HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.608 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Buffy coat peripheral blood leukocyte immunophenotyping / Treg cell CD25+ percentage HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.933 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Number of pelvic vertebrae HOM 7f:7m 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI X-ray / Shape of ribcage HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Salmonella Challenge / Liver bacterial count HOM 2f:2m Not processed 1.00 FAILED - Not enough mutant or control data
Fbxl7tm1a(EUCOMM)Wtsi WTSI Combined SHIRPA and Dysmorphology / Dorsal coat/hair length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fbxl7tm1a(EUCOMM)Wtsi WTSI Hematology / White blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.335 Success
Fbxl7tm1a(EUCOMM)Wtsi WTSI Trabecular Bone MicroCT / Bone Volume/Tissue Volume (%) HOM 4f:0m Mixed Model framework, generalized least squares, equation withoutWeight 0.149 Success

 Expression

Expression data not available

 Associated Images

Brain Histopathology: Hippocampal section
3 Images
Brain Histopathology: Striatal Section
2 Images
X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Fbxl7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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