Fan1 - FANCD2/FANCI-associated nuclease 1 | International Mouse Phenotyping Consortium

Genes Phenotypes

Gene: Fan1

Significant phenotypes (0)
All measurements (174)

No results meet the p-value threshold

Filtered by: all phenotypes

Chart Table

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Allele	Center	Procedure / Parameter	Zygosity	Mutants	Statistical Method	P Value	Status
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Tail - thickness	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb digit - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Alanine aminotransferase	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.407	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair distribution - back	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb nail - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Electrocardiogram (ECG) / RR	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.456	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Head bobbing	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - whole body	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Trunk curl	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Creatinine	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.434	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Lean/Body weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.561	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of thoracic vertebrae	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of ribs right	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - ear	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Distance travelled - total	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.516	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Snout size	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Electrocardiogram (ECG) / PR	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.121	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / Click-evoked ABR threshold	HOM	3f:3m		0.669	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / 24kHz-evoked ABR Threshold	HOM	3f:3m		1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Total cholesterol	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.000492	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Genitalia - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Periphery permanence time	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.434	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Radius	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Albumin	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.134	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb nail - length	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Electrocardiogram (ECG) / HR	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.441	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.719	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Fibula	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Percentage center time	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.435	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / 6kHz-evoked ABR Threshold	HOM	3f:3m		1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Shape of vertebrae	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Aggression	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Body length	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.536	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Brachydactyly	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Pelvis	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Vibrissae - presence	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Grip Strength / Forelimb grip strength measurement mean	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.455	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimbs - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Startle response	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Lower teeth appearance	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Scapulae	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Lens Opacity	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - back paws	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimbs - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb digit - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color - back	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Periphery distance travelled	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.370	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Femur	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Cornea	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Retina (combined)	HOM	9f:7m	Not processed		Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Center permanence time	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.435	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / 12kHz-evoked ABR Threshold	HOM	3f:3m		1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindpaw - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Zygomatic bone	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Calcium	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.849	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull)	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.344	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Upper lip morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Locomotor activity	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.921	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Shape of ribs	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Contact righting	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - ear	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb nail - number	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Grip Strength / Forelimb and hindlimb grip strength normalised against body weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.387	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - tail	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Vibrissae - appearance	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.358	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color - abdomen	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Retinal Blood Vessels	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Fat mass	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.234	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / 30kHz-evoked ABR Threshold	HOM	3f:3m		1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Phosphorus	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.725	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindpaw - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Mandibles	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Tremor	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Viability Primary Screen / Outcome	HOM	146f:127m	Supplied as data		Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Genitalia - morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Humerus	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - back paws	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Limb grasp	HOM	9f:7m	Fisher Exact Test framework	0.375	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Head morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Electrocardiogram (ECG) / ST	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.851	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - whole body	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Indirect Calorimetry / Respiratory Exchange Ratio	HOM	0f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.903	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Upper teeth appearance	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Center distance travelled	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.819	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Auditory Brain Stem Response / 18kHz-evoked ABR Threshold	HOM	3f:3m		1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of digits	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Triglycerides	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.000455	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN)	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.876	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color pattern - head	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Clavicle	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Genitalia - presence	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of lumbar vertebrae	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Activity (body position)	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb nail - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Ulna	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair distribution - head	HOM	9f:7m	Fisher Exact Test framework	0.157	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb digit - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Alkaline phosphatase	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.747	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb digit - number	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Digit integrity	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Tail - length	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Number of rears - total	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.0965	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Unexpected behaviors	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Teeth	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - snout	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Total protein	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.0809	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of ribs left	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Fat/Body weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.219	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimbs - position	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimbs - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of cervical vertebrae	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin texture - front paws	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Bone Area	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.00827	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color - head	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimbs - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb digit - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.235	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forepaw - size	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Fusion of vertebrae	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Tibia	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Tail - morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Total bilirubin	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.000348	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Aspartate aminotransferase	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.263	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimbs - position	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Hindlimb nail - length	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Fusion of ribs	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Vocalization	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / BMC/Body weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.0146	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Grip Strength / Forelimb and hindlimb grip strength measurement mean	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.103	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Lower lip morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - front paws	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Whole arena resting time	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.609	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Syndactylism	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Teeth presence	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Lens	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Grip Strength / Forelimb grip strength normalised against body weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.771	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Head size	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Optic Disc	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - color pattern - back	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / Glucose	HOM	8f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.364	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Center average speed	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.198	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Retinal Blood Vessels Structure	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Fertility of Homozygous Knock-out Mice / Gross Findings Female	HOM	f:m	Supplied as data		Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Joints	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Heart Weight / Heart weight	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withWeight	0.868	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Skull shape	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forepaw - shape	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb nail - number	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull)	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.00274	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Gait	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Electrocardiogram (ECG) / QRS	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.641	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Ears	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - snout	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Forelimb digit - number	HOM	9f:7m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Tail - presence	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Clinical Chemistry / HDL-cholesterol	HOM	7f:6m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.00464	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Insulin Blood Level / Insulin	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.587	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Periphery average speed	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.537	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Fertility of Homozygous Knock-out Mice / Gross Findings Male	HOM	f:m	Supplied as data		Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Processes on vertebrae	HOM	5f:5m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Tibia length	HOM	5f:5m	Mixed Model framework, generalized least squares, equation withWeight	0.00198	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Body Composition (DEXA lean/fat) / Lean mass	HOM	9f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.255	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Eye Morphology / Corneal opacity	HOM	9f:7m	Fisher Exact Test framework	0.0979	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Open Field / Whole arena average speed	HOM	8f:7m	Mixed Model framework, linear mixed-effects model, equation withoutWeight	0.516	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Maxilla/Pre-maxilla	HOM	5f:5m	Fisher Exact Test framework	1.00	Success
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	X-ray / Number of pelvic vertebrae	HOM	5f:5m	Not processed	1.00	FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Skin color - tail	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK
Fan1^{tm1b(KOMP)Wtsi}	UC Davis	Combined SHIRPA and Dysmorphology / Mouth morphology	HOM	9f:7m	Fisher Exact Test framework	1.00	Not tested (No variation) - OK

Expression

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	1	No	(2/584)		N/A
Aorta	1	No			N/A
Blood	1	No			N/A
Bone marrow	1	No			N/A
Brain	1	No			N/A
Brainstem	1	No			N/A
Brown adipose tissue	1	No			N/A
Cartilage tissue	1	No			N/A
Cecum	1	No	(12/383)		N/A
Cerebellum	1	No			N/A
Cerebral cortex	1	No			N/A
Chest bone	1	No			N/A
Colon	1	No	(12/127)		N/A
Diaphragm	1	No			N/A
Duodenum	1	No	(2/127)		N/A
Epididymis	1	No	(18/134)	(1/1)	N/A
Esophagus	1	No	(7/415)		N/A
Eye	1	No			N/A
Gall bladder	1	No			N/A
Gonadal fat pad	1	No			N/A
Harderian gland	1	No			N/A
Heart	1	No			N/A
Hindlimb	1	No			N/A
Hippocampus	1	No			N/A
Hypothalamus	1	No			N/A
Ileum	1	No	(14/127)		N/A
Jejunum	1	No	(6/127)		N/A
Kidney	1	No	(18/584)		N/A
Large intestine	1	No	(10/584)		N/A
Liver	1	No			N/A
Lower urinary tract	1	No			N/A
Lung	1	No			N/A
Lymph node	1	No			N/A
Mammary gland	1	No			N/A
Mesenteric adipose tissue	1	No			N/A
Mesenteric lymph node	1	No			N/A
Midbrain	1	No			N/A
Olfactory lobe	1	No			N/A
Ovary	1	No	(1/584)		N/A
Oviduct	1	No			N/A
Pancreas	1	No	(5/584)		N/A
Parathyroid gland	1	No			N/A
Parotid gland	1	No			N/A
Penis	1	No			N/A
Peripheral nervous system	1	No			N/A
Peyer's patch	1	No			N/A
Pituitary gland	1	No			N/A
Prostate gland	1	No	(12/584)		N/A
Quadriceps	1	No			N/A
Sciatic nerve	1	No			N/A
Skeletal muscle	1	No			N/A
Skin	1	No			N/A
Small intestine	1	No	(9/584)		N/A
Spinal cord	1	No			N/A
Spleen	1	No	(2/584)		N/A
Stomach	1	No	(12/584)		N/A
Stomach pyloric region	1	No			N/A
Striatum	1	No			N/A
Sublingual gland	1	No			N/A
Submandibular gland	1	No	(2/132)		N/A
Testis	1	No	(2/584)	(1/1)	N/A
Thymus	1	No			N/A
Thyroid gland	1	No	(15/584)		N/A
Tongue	1	No	(5/127)		N/A
Trachea	1	No			N/A
Trigeminal V nerve	1	No			N/A
Urinary bladder	1	No			N/A
Uterus	1	No			N/A
Vagina	1	No			N/A
Vas deferens	1	No	(15/388)	(1/1)	N/A
Vascular system	1	No			N/A
Vesicular gland	1	No			N/A
White adipose tissue	1	No			N/A

LacZ Wholemount Images

LacZ Section Images

No Embryo expression data was found for this gene.

Associated Images

X-ray: XRay Images Lateral Orientation
20 Images

X-ray: XRay Images Dorso Ventral
40 Images

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

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Order Mouse and ES Cells

MGI Allele	Allele Type	Availability
Fan1^{tm1b(KOMP)Wtsi}	Reporter-tagged deletion allele (post-Cre)	Mice, Tissue
Fan1^{tm1e(KOMP)Wtsi}	Targeted, non-conditional allele	Mice
Fan1^{tm1a(KOMP)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors, ES Cells

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