Gene: Fan1

Name
FANCD2/FANCI-associated nuclease 1
MGI ID
MGI:3045266
Synonyms
6030441H18Rik Mtmr15
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - thickness HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Alanine aminotransferase HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.407 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / RR HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.456 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head bobbing HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Trunk curl HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Creatinine HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.434 Success
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.561 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Distance travelled - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.516 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Snout size HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / PR HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.121 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 3f:3m 0.669 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 3f:3m 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total cholesterol HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000492 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Periphery permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.434 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Albumin HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.134 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / HR HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.441 Success
Fan1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.719 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Percentage center time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.435 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 3f:3m 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Aggression HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Body length HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.536 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength measurement mean HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.455 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Startle response HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Lens Opacity HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - back HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Periphery distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.370 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Cornea HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retina (combined) HOM 9f:7m Not processed Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Center permanence time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.435 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 3f:3m 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Calcium HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.849 Success
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.344 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Locomotor activity HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.921 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Contact righting HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - ear HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.387 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.358 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.234 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 3f:3m 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Phosphorus HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.725 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tremor HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Viability Primary Screen / Outcome HOM 146f:127m Supplied as data Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Limb grasp HOM 9f:7m Fisher Exact Test framework 0.375 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head morphology HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / ST HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.851 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.903 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Center distance travelled HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.819 Success
Fan1tm1b(KOMP)Wtsi UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 3f:3m 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Triglycerides HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000455 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.876 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Activity (body position) HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 9f:7m Fisher Exact Test framework 0.157 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Alkaline phosphatase HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.747 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - length HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Number of rears - total HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0965 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total protein HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0809 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.219 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00827 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color - head HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.235 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - size HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - morphology HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Total bilirubin HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000348 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Aspartate aminotransferase HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.263 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Vocalization HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0146 Success
Fan1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.103 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Whole arena resting time HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.609 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Teeth presence HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Lens HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Grip Strength / Forelimb grip strength normalised against body weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.771 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Head size HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Optic Disc HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / Glucose HOM 8f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.364 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Center average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.198 Success
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Heart Weight / Heart weight HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.868 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00274 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Gait HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Electrocardiogram (ECG) / QRS HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.641 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Ears HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - snout HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 9f:7m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Tail - presence HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Clinical Chemistry / HDL-cholesterol HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00464 Success
Fan1tm1b(KOMP)Wtsi UC Davis Insulin Blood Level / Insulin HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.587 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Periphery average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.537 Success
Fan1tm1b(KOMP)Wtsi UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Tibia length HOM 5f:5m Mixed Model framework, generalized least squares, equation withWeight 0.00198 Success
Fan1tm1b(KOMP)Wtsi UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 9f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.255 Success
Fan1tm1b(KOMP)Wtsi UC Davis Eye Morphology / Corneal opacity HOM 9f:7m Fisher Exact Test framework 0.0979 Success
Fan1tm1b(KOMP)Wtsi UC Davis Open Field / Whole arena average speed HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.516 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Fan1tm1b(KOMP)Wtsi UC Davis X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Skin color - tail HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Fan1tm1b(KOMP)Wtsi UC Davis Combined SHIRPA and Dysmorphology / Mouth morphology HOM 9f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584) N/A
Aorta 1 No N/A
Blood 1 No N/A
Bone marrow 1 No N/A
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/383) N/A
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127) N/A
Diaphragm 1 No N/A
Duodenum 1 No  (2/127) N/A
Epididymis 1 No  (18/134)  (1/1) N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No N/A
Harderian gland 1 No N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127) N/A
Jejunum 1 No  (6/127) N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No N/A
Lower urinary tract 1 No N/A
Lung 1 No N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No N/A
Mesenteric lymph node 1 No N/A
Midbrain 1 No N/A
Olfactory lobe 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Quadriceps 1 No N/A
Sciatic nerve 1 No N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132) N/A
Testis 1 No  (2/584)  (1/1) N/A
Thymus 1 No N/A
Thyroid gland 1 No  (15/584) N/A
Tongue 1 No  (5/127) N/A
Trachea 1 No N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Lateral Orientation
20 Images
X-ray: XRay Images Dorso Ventral
40 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Fan1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Fan1tm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Fan1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter