Gene: Znrf3 MGI:3039616

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
zinc and ring finger 3
Synonyms:
LOC382477

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Znrf3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Znrf3 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Cataract 20, Multiple Types
OMIM:116100
Cataract 29
OMIM:115800
Hereditary Hyperferritinemia-Cataract Syndrome
ORPHA:163
Cataract 36
OMIM:613887
Cataract 18
OMIM:610019
Cataract 35
OMIM:609376
Corneal Dystrophy, Groenouw Type I
OMIM:121900
Neural Tube Defects, Folate-Sensitive
OMIM:601634
Spina Bifida-Hypospadias Syndrome
ORPHA:3176
Cataract-Microcornea Syndrome
ORPHA:1377
Aniridia, Microcornea, And Spontaneously Reabsorbed Cataract
OMIM:106230
Megalocornea
OMIM:309300
Cataract 1, Multiple Types
OMIM:116200
Anterior Segment Dysgenesis 8
OMIM:617319
Exfoliation Syndrome
OMIM:177650
Glaucoma 3, Primary Congenital, D
OMIM:613086
Aniridia 2
OMIM:617141
Cataract 15, Multiple Types
OMIM:615274
Ectopia Lentis 2, Isolated, Autosomal Recessive
OMIM:225100
Ectopia Lentis 1, Isolated, Autosomal Dominant
OMIM:129600
Cataract 10, Multiple Types
OMIM:600881
Neural Tube Defects, X-Linked
OMIM:301410
Anencephaly 1
OMIM:206500
Aniridia-Intellectual Disability Syndrome
ORPHA:1068
Ectopia Lentis Et Pupillae
OMIM:225200
Anterior Segment Dysgenesis 2
OMIM:610256
Cataract 5, Multiple Types
OMIM:116800
Fryns Microphthalmia Syndrome
OMIM:600776
Aplasia Cutis Congenita
ORPHA:1114
Craniorachischisis
ORPHA:63260
Blepharocheilodontic Syndrome 1
OMIM:119580
Posterior Meningocele
ORPHA:268810
Iniencephaly
ORPHA:63259
Alobar Holoprosencephaly
ORPHA:93925
Lobar Holoprosencephaly
ORPHA:93924
Semilobar Holoprosencephaly
ORPHA:220386
Midline Interhemispheric Variant Of Holoprosencephaly
ORPHA:93926
Schinzel-Giedion Syndrome
ORPHA:798

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Znrf3

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Znrf3.

No publications found that use IMPC mice or data for Znrf3.

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MGI Allele Allele Type Produced
Znrf3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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