Genes Phenotypes

Gene: Tox3

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Name
TOX high mobility group box family member 3
MGI ID
MGI:3039593
Synonyms
Tnrc9 500-9 CAGF9
Viability
Homozygous - Viable Homozygous - Subviable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (227) All data table (1066)
Expression & images (42) Disease models (0) Order (5)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Tox3tm1b(KOMP)Mbp HOM Early adult 0.00
decreased circulating calcium level Tox3tm1b(KOMP)Mbp HET Early adult 6.31×10-07
hypoactivity Tox3em1(IMPC)Tcp HET Early adult 6.81×10-06
decreased bone mineral density Tox3em1(IMPC)Tcp HET Early adult 9.25×10-05

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No N/A
Cartilage tissue 2 No  (1/2)  Section images
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 1 No  (18/134)  (1/1) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (1/2) N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2) N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (1/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (1/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584)  (1/2) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
postnatal mouse (2)
Cartilage tissue expression
MA:0000104
set of connective tissues (2)
Cartilage tissue expression
MA:0000104
No Embryo expression data was found for this gene.

 Associated Images

Histopathology
2 Images
Adult LacZ: LacZ Images Section
2 Images
X-ray: XRay Images Whole Body Dorso Ventral
26 Images
X-ray: XRay Images Whole Body Lateral Orientation
42 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
16 Images
Combined SHIRPA and Dysmorphology
1 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
26 Images
Eye Morphology: Images Slit Lamp
3 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tox3tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Tox3em1(IMPC)Mbp Indel causing a Frameshift Mutation Mice
Tox3em1(IMPC)Tcp Indel causing a Frameshift Mutation Mice, Tissue
Tox3tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Tox3tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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