Or1e32 | olfactory receptor family 1 subfamily E member 32

GeneMGI:3030226Synonyms: GA_x6K02T2P1NL-3966976-3966038, MOR135-9, +1 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Integument Digestive/alimentary Vision/eye

15 No significant impact

3 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged cecum1 supporting datasetOr1e32em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal eye morphology1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged lymph nodes1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal cholesterol homeostasis1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adult2.64x10-5 
abnormal skin morphology1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal cecum morphology1 supporting datasetOr1e32em1(IMPC)MbphomozygoteEarly adultN/A * 
anophthalmia1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal adrenal gland morphology1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal lymph node morphology1 supporting datasetOr1e32em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Or1e32 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Or1e32em1(IMPC)MbpExon Deletionmouse
Or1e32tm51897(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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