Gene: Adamtsl3

Name
ADAMTS-like 3
MGI ID
MGI:3028499
Synonyms
punctin-2 9230119C12Rik
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (203) Expression & images (0) Disease models (0) Order (3)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Bulging eye HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0617 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Time mobile light side HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.751 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Iris/Pupil HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of thoracic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_014_001'.
Adamtsl3em1(IMPC)Tcp TCP X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0188 Success
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Body length HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.117 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Lens Opacity HOM 7f:8m Fisher Exact Test framework 0.000625 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.677 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Fear Conditioning / Conditioning Baseline % Freezing Time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.289 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Percent time in dark HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.325 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.706 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0280 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 0.118 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Pupil Dilation HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Fat mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00751 Success
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.213 Success
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.244 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Viability Primary Screen / Outcome HOM 19f:22m Supplied as data Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.136 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0590 Success
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 0.149 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Corneal vascularization HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / PQ HOM 8f:8m Mixed Model framework, generalized least squares, equation withWeight 0.848 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Pupil Position HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00359 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of cervical vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_013_001'.
Adamtsl3em1(IMPC)Tcp TCP Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.442 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Eyelid closure HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.747 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Dark side time spent HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.937 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Percent time in light HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.325 Success
Adamtsl3em1(IMPC)Tcp TCP Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.262 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Lens HOM 7f:8m Fisher Exact Test framework 0.0247 Success
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / QTc HOM 8f:8m Mixed Model framework, generalized least squares, equation withWeight 0.688 Success
Adamtsl3em1(IMPC)Tcp TCP Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0236 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Center average speed HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000446 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Narrow eye opening HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0408 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0611 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 0.364 Success
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.225 Success
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.509 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Pupil Shape HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / QTc Dispersion HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.357 Success
Adamtsl3em1(IMPC)Tcp TCP Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.859 Success
Adamtsl3em1(IMPC)Tcp TCP Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Eye HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000730 Success
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / rMSSD HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.290 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.271 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.00148 Success
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.655 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Synechia HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 0.0564 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0188 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0518 Success
Adamtsl3em1(IMPC)Tcp TCP Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.188 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0749 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000905 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Time mobile dark side HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.879 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Eyelid morphology HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Cornea HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0188 Success
Adamtsl3em1(IMPC)Tcp TCP Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 0.315 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0574 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Transition HOM 6f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00335 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Iris Pigmentation HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / HRV HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.599 Success
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.405 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of digits HOM 5f:5m 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0380 Success
Adamtsl3em1(IMPC)Tcp TCP Fear Conditioning / Cue Baseline % Freezing Time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.245 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of lumbar vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_015_001'.
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Light side time spent HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.937 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Number of rears - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.276 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 0.208 Success
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.258 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of ribs left HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_009_001'.
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Bone Area HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.773 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Fusion between cornea and lens HOM 7f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.400 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / CV HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.460 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0579 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Open Field / Center resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00171 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Latency to first transition into dark HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.437 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.962 Success
Adamtsl3em1(IMPC)Tcp TCP Fear Conditioning / Cue Tone % Freezing Time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.297 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Fear Conditioning / Context % Freezing Time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.230 Success
Adamtsl3em1(IMPC)Tcp TCP Light-Dark Test / Side changes HOM 6f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.598 Success
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Adamtsl3em1(IMPC)Tcp TCP Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 7f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.422 Success
Adamtsl3em1(IMPC)Tcp TCP Body Composition (DEXA lean/fat) / Lean mass HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00384 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Tibia length HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.524 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Pupil Light Response HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.478 Success
Adamtsl3em1(IMPC)Tcp TCP Eye Morphology / Corneal opacity HOM 7f:8m Fisher Exact Test framework 1.00 Success
Adamtsl3em1(IMPC)Tcp TCP X-ray / Number of pelvic vertebrae HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_016_001'.
Adamtsl3em1(IMPC)Tcp TCP Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Adamtsl3em1(IMPC)Tcp Exon Deletion Mice
Adamtsl3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Adamtsl3tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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