Gene: Ino80d

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Ino80dtm1b(EUCOMM)Wtsi HET Early adult 7.78×10-09
decreased startle reflex Ino80dtm1b(EUCOMM)Wtsi HET Early adult 4.99×10-06
abnormal embryo size Ino80dtm1b(EUCOMM)Wtsi HOM E18.5 0.00
increased bone mineral density Ino80dtm1b(EUCOMM)Wtsi HET Early adult 4.40×10-05
preweaning lethality, incomplete penetrance Ino80dtm1b(EUCOMM)Wtsi HOM Early adult 0.00
increased lean body mass Ino80dtm1b(EUCOMM)Wtsi HET Early adult 7.08×10-10
abnormal retinal outer nuclear layer morphology Ino80dtm1b(EUCOMM)Wtsi HET Early adult 9.46×10-11
decreased total retina thickness Ino80dtm1b(EUCOMM)Wtsi HET Early adult 2.22×10-09
decreased total body fat amount Ino80dtm1b(EUCOMM)Wtsi HET Early adult 5.16×10-10

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Wholemount images
Aorta 2 No  (1/590)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (1/590)  (2/2)  Wholemount images
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2)  Wholemount images
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (2/2)  Wholemount images
Prostate gland 2 No  (12/590)  (1/2)  Wholemount images
Skeletal muscle 2 No  (2/2)  Wholemount images
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/590)  (2/2)  Wholemount images
Trachea 2 No  (2/590)  (2/2)  Wholemount images
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2)  Wholemount images
Vas deferens 2 No  (15/388)  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/61)  (2/2) N/A
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 2  (6/506)  (2/2) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Cranium 2  (1/65)  (2/2) N/A
Dorsal root ganglion 2  (1/61)  (2/2) N/A
Ear 2  (1/506)  (2/2) N/A
Embryo 2  (1/507)  (2/2) N/A
Outer ear 2  (1/72)  (2/2) N/A
Eye 2  (1/506)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/56)  (2/2) N/A
Foot 2  (1/506)  (2/2) N/A
Forearm 2  (1/303)  (2/2) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506)  (2/2) N/A
Fronto-nasal process 2  (1/62)  (2/2) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 2  (1/506)  (2/2) N/A
Head 2  (5/506)  (2/2) N/A
Head mesenchyme 2  (1/61)  (2/2) N/A
Heart 2  (1/506)  (2/2) N/A
Heart ventricle 2  (1/61)  (2/2) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/506)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/65)  (2/2) N/A
Inner ear 2  (1/65)  (2/2) N/A
Intestine 2  (1/59)  (2/2) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/303)  (2/2) N/A
Lung 2  (1/504)  (2/2) N/A
Mandibular process 2  (1/506)  (2/2) N/A
Maxillary process 2  (1/506)  (2/2) N/A
Mesonephros of female 2  (1/56)  (1/2) N/A
Mesonephros of male 2  (1/56)  (1/2) N/A
Metanephros 2  (1/56)  (2/2) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nasal septum 2  (1/61)  (2/2) N/A
Nose 2  (1/76)  (2/2) N/A
Notochord 2  (1/61)  (2/2) N/A
Oral cavity 2  (1/504)  (2/2) N/A
Outflow tract 2  (1/61)  (2/2) N/A
Pancreas 2  (1/56)  (2/2) N/A
Pericardium 2  (1/56)  (2/2) N/A
Pharynx 2  (1/57)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/65)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/58)  (2/2) N/A
Skeleton 2  (1/76)  (2/2) N/A
Skin 2  (1/506)  (2/2) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Stomach 2  (1/56)  (2/2) N/A
Tail 2  (1/506)  (2/2) N/A
Tail somite 2  (1/506)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/56)  (2/2) N/A
Tongue 2  (1/56)  (2/2) N/A
Trachea 2  (1/60)  (2/2) N/A
Trunk mesenchyme 2  (1/61)  (2/2) N/A
Umbilical artery embryonic part 2  (1/61)  (2/2) N/A
Umbilical vein embryonic part 2  (1/61)  (2/2) N/A
Upper arm 2  (1/303)  (2/2) N/A
Upper leg 2  (1/303)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A
Vibrissa 2  (1/72)  (2/2) N/A

 Associated Images

Eye Morphology: VIP of right fundus
16 Images
Adult LacZ: LacZ Images Wholemount
15 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: VIP of left fundus
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Eye Morphology: VIP of left eye
16 Images
Eye Morphology: VIP of right eye
16 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ino80dtm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ino80dtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ino80dtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ino80dtm33693(L1L2_Bact_P) Targeting vectors

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