Gene: Pfkfb4

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Name
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
MGI ID
MGI:2687284
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
female infertility Pfkfb4tm1b(KOMP)Wtsi HOM Early adult 0.00
eye hemorrhage Pfkfb4tm1b(KOMP)Wtsi HOM Early adult 5.99×10-07

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 Yes  (2/511)  (3/4)  Wholemount images  Section images
Aorta 3 No  (1/499) N/A
Blood 3 No N/A
Bone marrow 3 No N/A
Brain 3 No  (4/504)  (2/4)  Wholemount images
Brainstem 3 No  (2/498) N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No  (1/507) N/A
Cecum 3 No  (8/312)  (2/4) N/A
Cerebellum 3 Yes  (3/499)  (4/4)  Wholemount images  Section images
Cerebral cortex 3 No  (2/510) N/A
Chest bone 3 No  (2/4)  Wholemount images
Colon 3 No  (9/105)  (2/4) N/A
Diaphragm 3 No N/A
Duodenum 3 No  (1/111)  (2/4)  Section images
Epididymis 3 Yes  (14/115)  (2/4)  Section images
Esophagus 3 Yes  (7/354)  (4/4)  Wholemount images  Section images
Eye 3 No  (1/4)  Section images
Gall bladder 3 No  (1/4)  Wholemount images
Gonadal fat pad 3 No N/A
Harderian gland 3 No N/A
Heart 3 No  (1/486) N/A
Hindlimb 3 No N/A
Hippocampus 3 No  (3/494) N/A
Hypothalamus 3 No  (2/492) N/A
Ileum 3 Yes  (12/110)  (2/4)  Section images
Jejunum 3 No  (5/110)  (2/4) N/A
Kidney 3 No  (18/493)  (3/4)  Wholemount images  Section images
Large intestine 3 No  (10/483) N/A
Liver 3 No N/A
Lower urinary tract 3 No  (1/505) N/A
Lung 3 No  (1/505)  (2/4)  Wholemount images  Section images
Lymph node 3 No  (1/522) N/A
Mammary gland 3 No N/A
Mesenteric adipose tissue 3 No N/A
Mesenteric lymph node 3 No N/A
Midbrain 3 Yes  (4/4)  Wholemount images  Section images
Olfactory lobe 3 Yes  (2/483)  (4/4)  Wholemount images  Section images
Ovary 3 No N/A
Oviduct 3 No  (1/4)  Wholemount images
Pancreas 3 No  (4/493) N/A
Parathyroid gland 3 No  (1/477)  (2/4)  Wholemount images
Parotid gland 3 No N/A
Penis 3 Yes  (1/4)  Section images
Peripheral nervous system 3 No  (2/501) N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No  (1/509)  (2/4)  Wholemount images  Section images
Prostate gland 3 Yes  (11/507)  (1/4)  Section images
Quadriceps 3 No N/A
Sciatic nerve 3 No  (1/4)  Wholemount images
Skeletal muscle 3 No N/A
Skin 3 Yes  (3/4)  Wholemount images  Section images
Small intestine 3 No  (7/504) N/A
Spinal cord 3 Yes  (3/492)  (4/4)  Wholemount images  Section images
Spleen 3 No  (3/499) N/A
Stomach 3 Yes  (12/496)  (4/4)  Section images
Stomach pyloric region 3 No N/A
Striatum 3 No  (2/505) N/A
Sublingual gland 3 No N/A
Submandibular gland 3 No  (2/110) N/A
Testis 3 Yes  (6/490)  (1/4)  Section images
Thymus 3 No  (1/502) N/A
Thyroid gland 3 No  (13/498) N/A
Tongue 3 Yes  (5/117)  (1/4)  Section images
Trachea 3 No  (2/504)  (1/4)  Section images
Trigeminal V nerve 3 Yes  (2/4)  Section images
Urinary bladder 3 Yes  (4/4)  Wholemount images  Section images
Uterus 3 No  (2/4)  Wholemount images  Section images
Vagina 3 No  (1/4)  Section images
Vas deferens 3 Yes  (12/320)  (2/4)  Section images
Vascular system 3 No N/A
Vesicular gland 3 Yes  (2/4)  Wholemount images  Section images
White adipose tissue 3 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
25 Images
Adult LacZ: LacZ Images Section
81 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
X-ray: XRay Images Skull Lateral Orientation
23 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
24 Images
Adult LacZ: LacZ Images Wholemount
32 Images
X-ray: XRay Images Forepaw
24 Images
Legacy Phenotype Associated Images

View all 70 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pfkfb4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Pfkfb4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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