Gene: Far2

Name fatty acyl CoA reductase 2

Synonyms Mlstd1

Status ES CellsMice
tm2a
Mice
tm2b
phenotype data available

Links MGI:2687035   Ensembl Gene   Ensembl Orthologs

Viability Homozygous - Viable

Phenotype associations for Far2

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Far2 data for that phenotype.

Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal coat appearance Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 3.54E-21
decreased circulating HDL cholesterol level Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 3.72E-8
decreased circulating cholesterol level Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 4.74E-8
decreased total body fat amount Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 1.69E-7
shortened RR interval Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 8.37E-7
increased heart rate Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 3.45E-6
cardiovascular system phenotype Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 5.06E-6
increased lean body mass Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 7.81E-6
decreased heart rate variability Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 1.16E-5
abnormal sleep behavior Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 3.17E-5
decreased vertical activity Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 5.25E-5
decreased coping response Far2tm2b(KOMP)Wtsi HOM Female Male postnatal 8.78E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393)
Aorta 2 No (1/562)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562)
Brown adipose tissue 2 No
Cartilage tissue 2 No (1/562)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562)
Epididymis 2 No (4/106)
Esophagus 2 No (2/393)
Eye 2 No (1/562)
Heart 2 No (3/562)
Hippocampus 2 No (5/562)
Hypothalamus 2 No (4/562)
Kidney 2 No (20/562)
Large intestine 2 No (12/562)
Liver 2 No
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562)
Lymph node 2 No (1/562)
Mammary gland 2 No
Midbrain 2 No
Olfactory lobe 2 No (4/393)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562)
Pancreas 2 No (6/562)
Peripheral nervous system 2 No (3/562)
Peyer's patch 2 No (1/393)
Pituitary gland 2 No (1/562)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562)
Spinal cord 2 No (3/562)
Spleen 2 No (4/562)
Stomach 2 No (9/562)
Striatum 2 No (4/562)
Submandibular gland 2 No (1/104)
Testis 2 No (4/562)
Thalamus 2 No
Thymus 2 No
Thyroid gland 2 No (16/562)
Trachea 2 No (3/562)
Urinary bladder 2 No
Uterus 2 No (2/562)
Vascular system 2 No (1/393)
Vesicular gland 2 No
White adipose tissue 2 No
Expression in Anatomogram

Tissues/organs lacZ+ expression

    postnatal mouse
    nervous system
    reproductive system
    integumental system
    trunk
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2 (6/440)
Dorsal root ganglion 1 (1/3)
Ear 2 (1/440)
Embryo 2 (1/440)
Eye 2 (1/440)
Foot 2
Forebrain 2 (1/440)
Forelimb 2 (1/440)
Fronto-nasal process 1 (1/4)
Hand 2
Head 2 (5/440)
Heart 2 (1/440)
Hindbrain 2 (5/440)
Hindlimb 2 (1/440)
Liver 2 (1/440)
Lung 2 (1/440)
Mandibular process 2 (1/440)
Maxillary process 2 (1/440)
Midbrain 2 (1/440)
Nose 1 (1/5)
Oral cavity 2 (1/440)
Skin 2 (1/440)
Spinal cord 1 (1/4)
Tail 2 (1/440)
Tail somite 2 (1/440)


Associated Images

Associated Images
  • Combined SHIRPA and Dysmorphology
    30 Images
  • Embryo LacZ: LacZ images wholemount
    4 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • Sleep Wake: Wake state (bmp file)
    12 Images
  • X-ray: XRay Images Skull Lateral Orientation
    12 Images
  • Electroretinography: Cone waveform (pdf format)
    2 Images
  • Electroretinography: Rod waveform (pdf format)
    2 Images

Disease Models

No associations by disease annotation and gene orthology found.

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Far2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Far2tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene
Far2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene