Gene: Far2
Name fatty acyl CoA reductase 2
Synonyms
Mlstd1
Status
ES CellsMice
tm2aMice
tm2bphenotype data available
Links MGI:2687035 Ensembl Gene Ensembl Orthologs
Viability Homozygous - Viable
Phenotype associations for Far2
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Far2 data for that phenotype.
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
abnormal coat appearance | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 3.54E-21 | |
|
|
decreased circulating HDL cholesterol level | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 3.72E-8 | |
|
|
decreased circulating cholesterol level | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 4.74E-8 | |
|
|
decreased total body fat amount | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 1.71E-7 | |
|
|
shortened RR interval | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 9.58E-7 | |
|
|
increased heart rate | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 3.94E-6 | |
|
|
cardiovascular system phenotype | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 4.88E-6 | |
|
|
increased lean body mass | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 7.84E-6 | |
|
|
decreased heart rate variability | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 1.17E-5 | |
|
|
abnormal sleep behavior | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 3.17E-5 | |
|
|
decreased vertical activity | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 5.48E-5 | |
|
|
decreased coping response | Far2tm2b(KOMP)Wtsi | HOM |
|
postnatal | 8.78E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (5/393) | ||
| Aorta | 2 | No | (1/562) | ||
| Brain | 2 | No | (5/562) | (2/2) | |
| Brainstem | 2 | No | (4/562) | ||
| Brown adipose tissue | 2 | No | |||
| Cartilage tissue | 2 | No | (1/562) | ||
| Cerebellum | 2 | No | (4/562) | (2/2) | |
| Cerebral cortex | 2 | No | (5/562) | ||
| Epididymis | 2 | No | (4/106) | ||
| Esophagus | 2 | No | (2/393) | ||
| Eye | 2 | No | (1/562) | ||
| Heart | 2 | No | (3/562) | ||
| Hippocampus | 2 | No | (5/562) | ||
| Hypothalamus | 2 | No | (4/562) | ||
| Kidney | 2 | No | (19/562) | ||
| Large intestine | 2 | No | (12/562) | ||
| Liver | 2 | No | |||
| Lower urinary tract | 2 | No | (3/562) | ||
| Lung | 2 | No | (3/562) | ||
| Lymph node | 2 | No | (1/562) | ||
| Mammary gland | 2 | No | |||
| Midbrain | 2 | No | |||
| Olfactory lobe | 2 | No | (4/393) | ||
| Ovary | 2 | No | (1/562) | (1/2) | |
| Oviduct | 2 | No | (2/562) | ||
| Pancreas | 2 | No | (6/562) | ||
| Peripheral nervous system | 2 | No | (3/562) | ||
| Peyer's patch | 2 | No | (1/393) | ||
| Pituitary gland | 2 | No | (1/562) | ||
| Prostate gland | 2 | No | (5/562) | ||
| Skeletal muscle | 2 | No | |||
| Skin | 2 | No | (1/562) | (2/2) | |
| Small intestine | 2 | No | (11/562) | ||
| Spinal cord | 2 | No | (3/562) | ||
| Spleen | 2 | No | (4/562) | ||
| Stomach | 2 | No | (9/562) | ||
| Striatum | 2 | No | (4/562) | ||
| Submandibular gland | 2 | No | (1/104) | ||
| Testis | 2 | No | (3/562) | ||
| Thalamus | 2 | No | |||
| Thymus | 2 | No | |||
| Thyroid gland | 2 | No | (16/562) | ||
| Trachea | 2 | No | (3/562) | ||
| Urinary bladder | 2 | No | |||
| Uterus | 2 | No | (2/562) | ||
| Vascular system | 2 | No | (1/393) | ||
| Vesicular gland | 2 | No | |||
| White adipose tissue | 2 | No |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Brain | 2 | (5/439) | ||
| Dorsal root ganglion | 1 | Image Only | ||
| Ear | 2 | |||
| Embryo | 2 | |||
| Eye | 2 | |||
| Foot | 2 | |||
| Forebrain | 2 | |||
| Forelimb | 2 | |||
| Fronto-nasal process | 1 | |||
| Hand | 2 | |||
| Head | 2 | (4/439) | ||
| Heart | 2 | |||
| Hindbrain | 2 | (5/439) | ||
| Hindlimb | 2 | |||
| Liver | 2 | |||
| Lung | 2 | |||
| Mandibular process | 2 | |||
| Maxillary process | 2 | |||
| Midbrain | 2 | |||
| Nose | 1 | Image Only | ||
| Oral cavity | 2 | |||
| Skin | 2 | |||
| Spinal cord | 1 | Image Only | ||
| Tail | 2 | |||
| Tail somite | 2 |
Associated Images
Associated Images
-
X-ray: XRay Images Skull Lateral Orientation
12 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
-
Combined SHIRPA and Dysmorphology
30 Images
-
X-ray: XRay Images Lateral Orientation
12 Images
-
Sleep Wake: Wake state (bmp file)
12 Images
-
Electroretinography: Rod waveform (pdf format)
2 Images
-
X-ray: XRay Images Dorso Ventral
12 Images
-
X-ray: XRay Images Forepaw
12 Images
-
Electroretinography: Cone waveform (pdf format)
2 Images
-
Embryo LacZ: LacZ images wholemount
4 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Far2tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
|
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| Far2tm2b(KOMP)Wtsi | Reporter-tagged deletion allele (post-Cre) |
|
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| Far2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
|
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