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Gene: Far2

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Name
fatty acyl CoA reductase 2
MGI ID
MGI:2687035
Synonyms
Mlstd1
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (15) Measurements chart (201) All data table (448)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating HDL cholesterol level Far2tm2b(KOMP)Wtsi HOM Early adult 1.99×10-10
abnormal sleep behavior Far2tm2b(KOMP)Wtsi HOM   Early adult 3.49×10-07
abnormal sinus arrhythmia Far2tm2b(KOMP)Wtsi HOM Early adult 6.70×10-05
cardiovascular system phenotype Far2tm2b(KOMP)Wtsi HOM Early adult 2.24×10-07
hypoactivity Far2tm2b(KOMP)Wtsi HOM Early adult 8.72×10-07
abnormal coat appearance Far2tm2b(KOMP)Wtsi HOM Early adult 2.84×10-19
increased heart rate Far2tm2b(KOMP)Wtsi HOM Early adult 6.70×10-09
decreased coping response Far2tm2b(KOMP)Wtsi HOM   Early adult 1.05×10-05
shortened RR interval Far2tm2b(KOMP)Wtsi HOM Early adult 1.48×10-09
increased fasting circulating glucose level Far2tm2b(KOMP)Wtsi HOM Early adult 8.46×10-05
increased lean body mass Far2tm2b(KOMP)Wtsi HOM   Early adult 2.09×10-05
decreased vertical activity Far2tm2b(KOMP)Wtsi HOM Early adult 2.76×10-06
decreased total body fat amount Far2tm2b(KOMP)Wtsi HOM Early adult 2.57×10-05
decreased heart rate variability Far2tm2b(KOMP)Wtsi HOM Early adult 1.10×10-06
decreased circulating cholesterol level Far2tm2b(KOMP)Wtsi HOM   Early adult 3.44×10-08

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583) N/A
Epididymis 2 No  (18/132) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583) N/A
Thalamus 2 No N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
integumental system (1)
Skin expression
MA:0000151
nervous system (2)
Brain expression
MA:0000168
postnatal mouse (4)
Brain expression
MA:0000168
reproductive system (1)
Ovary expression
MA:0000384
trunk (1)
Ovary expression
MA:0000384
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505) N/A
1  (1/60) N/A
2  (1/505) N/A
2  (1/506)  Wholemount images
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
1  (1/61) N/A
2  (1/505) N/A
2  (5/505) N/A
2  (1/505) N/A
2  (6/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
1  (1/75) N/A
2  (1/503) N/A
2  (1/505) N/A
1  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A
embryo or Unassigned (4)
Embryo imageOnly

 Associated Images

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X-ray: XRay Images Skull Lateral Orientation
12 Images
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Eye Morphology: Images Slit Lamp
4 Images
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X-ray: XRay Images Forepaw
12 Images
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Combined SHIRPA and Dysmorphology
30 Images
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X-ray: XRay Images Whole Body Lateral Orientation
12 Images
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Eye Morphology: Images Ophthalmoscopy
5 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
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X-ray: XRay Images Whole Body Dorso Ventral
12 Images
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Embryo LacZ: LacZ images wholemount
4 Images
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Sleep Wake: Wake state (bmp file)
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Far2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Far2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Far2tm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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