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Gene: Mroh7 MGI:2685873

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Gene Summary

Name:
maestro heat-like repeat family member 7
Synonyms:
LOC381538,  Heatr8,  Gm1027

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Legacy Phenotype Associated Images
Mroh7tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Mroh7tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Mroh7tm1a(EUCOMM)Wtsi
HOM, Male, WTSI
Mroh7tm1a(EUCOMM)Wtsi
HOM, Female, WTSI
Mroh7tm1a(EUCOMM)Wtsi
body, HOM, Female, WTSI

View all 71 images

Mroh7tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Mroh7tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI

Human diseases caused by Mroh7 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Mroh7

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mroh7.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. Nature communications (August 2019) Mroh7tm1a(EUCOMM)Wtsi PMC6671969
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS biology (April 2019) Mroh7tm1a(EUCOMM)Wtsi PMC6459510

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MGI Allele Allele Type Produced
Mroh7tm39135(L1L2_gt1) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Mroh7tm47191(L1L2_gt0) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Mroh7tm1e(EUCOMM)Wtsi Targeted, non-conditional allele ES Cells
Mroh7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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