Gene Summary

Name:
GRB2 associated regulator of MAPK1 subtype 1
Synonyms:
LOC381126,  Fam59a,  Garem

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal spleen morphology Garem1em1(IMPC)Mbp HOM Early adult 0.00
abnormal kidney morphology Garem1em1(IMPC)Mbp HOM Early adult 0.00
small liver Garem1em1(IMPC)Mbp HOM Early adult 0.00
small kidney Garem1em1(IMPC)Mbp HOM Early adult 0.00
small spleen Garem1em1(IMPC)Mbp HOM Early adult 0.00
abnormal skin morphology Garem1em1(IMPC)Mbp HOM Early adult 0.00
abnormal liver morphology Garem1em1(IMPC)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Garem1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Garem1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Garem1.

No publications found that use IMPC mice or data for Garem1.

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MGI Allele Allele Type Produced
Garem1em1(IMPC)Mbp Exon Deletion Mice
Garem1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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