Gene: Colca2

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Name
COLCA2 homolog
MGI ID
MGI:2685530
Synonyms
LOC270157 Gm684
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Colca2tm1b(NCOM)Mfgc HOM Early adult 1.31×10-06
cardiovascular system phenotype Colca2tm1b(NCOM)Mfgc HOM Early adult 1.09×10-05
decreased prepulse inhibition Colca2tm1b(NCOM)Mfgc HOM Early adult 1.39×10-06
increased grip strength Colca2tm1b(NCOM)Mfgc HOM Early adult 2.11×10-06
abnormal behavior Colca2tm1b(NCOM)Mfgc HOM Early adult 5.00×10-05
decreased startle reflex Colca2tm1b(NCOM)Mfgc HOM Early adult 2.87×10-11
decreased bone mineral density Colca2tm1b(NCOM)Mfgc HOM Early adult 4.23×10-07
decreased bone mineral content Colca2tm1b(NCOM)Mfgc HOM Early adult 2.19×10-15
decreased fasting circulating glucose level Colca2tm1b(NCOM)Mfgc HOM Early adult 1.31×10-05
increased heart rate variability Colca2tm1b(NCOM)Mfgc HOM Early adult 2.13×10-05
male infertility Colca2tm1b(NCOM)Mfgc HOM Early adult 0.00
short tibia Colca2tm1b(NCOM)Mfgc HOM Early adult 2.96×10-06
abnormal bone structure Colca2tm1b(NCOM)Mfgc HOM Early adult 7.56×10-10
decreased body length Colca2tm1b(NCOM)Mfgc HOM Early adult 2.58×10-10

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Histopathology
7 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
3 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Epididymis - process of degenerative change Colca2tm1b(NCOM)Mfgc HOM Early adult
Testes - process of degenerative change Colca2tm1b(NCOM)Mfgc HOM Early adult
Small intestine - inflammation Colca2tm1b(NCOM)Mfgc HOM Early adult

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MGI Allele Allele Type Produced
Colca2tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Colca2tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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