Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
golgi-associated olfactory signaling regulator
Synonyms:
N/A

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Gfy mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Gfy by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Leber Congenital Amaurosis 10
Hyposmia OMIM:611755
Anosmia For Isobutyric Acid
Partial anosmia OMIM:207000
Anosmia For Butyl Mercaptan
Anosmia OMIM:270350
Isovaleric Acid, Inability To Smell
Anosmia OMIM:243450
Anosmia, Isolated Congenital
Anosmia OMIM:301700
Anosmia, Isolated Congenital
Anosmia OMIM:107200
Musk, Inability To Smell
Anosmia OMIM:254150
Freesia Flowers, Inability To Smell
Specific anosmia OMIM:229250
Hypogonadotropic Hypogonadism 10 With Or Without Anosmia
Anosmia OMIM:614839
Thumb Agenesis, Short Stature, And Immunodeficiency
Anosmia OMIM:274190
Body Mass Index Quantitative Trait Locus 19
Hyposmia, Anosmia OMIM:617885
Aural Atresia, Congenital
Hyposmia OMIM:607842
Hypogonadotropic Hypogonadism 13 With Or Without Anosmia
Anosmia OMIM:614842
Hypogonadotropic Hypogonadism 14 With Or Without Anosmia
Anosmia OMIM:614858
Hypogonadotropic Hypogonadism 18 With Or Without Anosmia
Hyposmia, Anosmia OMIM:615267
Dermoid Cysts, Familial Frontonasal
Nasal congestion, Anosmia, Deviated nasal septum, Wide nasal bridge OMIM:600679
Hypogonadotropic Hypogonadism 16 With Or Without Anosmia
Hyposmia, Anosmia, Azoospermia OMIM:614897
Bardet-Biedl Syndrome 19
Hyposmia OMIM:615996
Apnea, Obstructive Sleep
Anosmia OMIM:107650
Brachytelephalangy With Characteristic Facies And Kallmann Syndrome
Anosmia, Depressed nasal bridge OMIM:113480
Hypogonadotropic Hypogonadism 5 With Or Without Anosmia
Anosmia OMIM:612370
Hypogonadotropic Hypogonadism 22 With Or Without Anosmia
Anosmia OMIM:616030
Chondrodysplasia Punctata 1, X-Linked Recessive
Anosmia, Short nasal septum, Short nose, Depressed nasal bridge OMIM:302950
Arrhinia-Choanal Atresia-Microphthalmia Syndrome
Aplasia/Hypoplasia involving the nose, Abnormality of the sense of smell, Choanal atresia ORPHA:1135
Hypogonadotropic Hypogonadism 9 With Or Without Anosmia
Hyposmia, Anosmia OMIM:614838
Hypogonadotropic Hypogonadism 6 With Or Without Anosmia
Hyposmia, Anosmia OMIM:612702
Asthma, Nasal Polyps, And Aspirin Intolerance
Nasal polyposis OMIM:208550
Indifference To Pain, Congenital, Autosomal Recessive
Hyposmia, Anosmia OMIM:243000
Leukoencephalopathy With Dystonia And Motor Neuropathy
Hyposmia, Azoospermia OMIM:613724
Neuropathy, Hereditary Sensory And Autonomic, Adult-Onset, With Anosmia
Hyposmia, Anosmia OMIM:608720
Peroxisome Biogenesis Disorder 9B
Anosmia OMIM:614879
Hypogonadotropic Hypogonadism 4 With Or Without Anosmia
Anosmia OMIM:610628
Hypogonadotropic Hypogonadism 8 With Or Without Anosmia
Anosmia, Azoospermia OMIM:614837
Ciliary Dyskinesia, Primary, 1
Bronchiectasis, Nasal polyposis, Anosmia, Pneumonia, Sinusitis, Chronic rhinitis, Chronic sinusit... OMIM:244400
Blepharophimosis-Ptosis-Esotropia-Syndactyly-Short Stature Syndrome
Anosmia ORPHA:2057
Blepharophimosis With Ptosis, Syndactyly, And Short Stature
Anosmia, Wide nasal bridge OMIM:210745
Hypogonadotropic Hypogonadism 25 With Anosmia
Anosmia OMIM:618841
Hypogonadotropic Hypogonadism 3 With Or Without Anosmia
Anosmia OMIM:244200
Ciliary Dyskinesia, Primary, 35
Bronchiectasis, Nasal polyposis, Chronic rhinitis, Chronic sinusitis, Recurrent respiratory infec... OMIM:617092
Ciliary Dyskinesia With Excessively Long Cilia
Recurrent bronchitis, Nasal polyposis, Chronic rhinitis, Sinusitis, Abnormal respiratory motile c... OMIM:242680
Solitary Median Maxillary Central Incisor
Abnormal nasopharynx morphology, Anosmia, Pyriform aperture stenosis, Choanal atresia, Midnasal s... OMIM:147250
Parkinson Disease 8, Autosomal Dominant
Hyposmia OMIM:607060
Hypogonadotropic Hypogonadism 2 With Or Without Anosmia
Anosmia, Choanal atresia OMIM:147950
Ciliary Dyskinesia, Primary, 5
Recurrent bronchitis, Respiratory tract infection, Bronchiectasis, Nasal polyposis, Recurrent sin... OMIM:608647
Hyperostosis Cranialis Interna
Hyposmia OMIM:144755
Brachytelephalangy-Dysmorphism-Kallmann Syndrome
Anosmia, Short nose, Abnormality of the nares ORPHA:1295
Gorlin Syndrome
Abnormality of the sense of smell, Wide nasal bridge ORPHA:377
Ventricular Extrasystoles With Syncopal Episodes-Perodactyly-Robin Sequence Syndrome
Abnormality of the sense of smell ORPHA:3201
Bare Lymphocyte Syndrome, Type I
Recurrent bronchitis, Bronchiectasis, Bronchiolitis, Nasal polyposis, Emphysema, Chronic sinusitis OMIM:604571
Ciliary Dyskinesia, Primary, 42
Bronchiectasis, Nasal polyposis, Recurrent sinusitis, Pneumonia, Chronic rhinitis OMIM:618695
Ciliary Dyskinesia With Defective Radial Spokes
Absent respiratory ciliary axoneme radial spokes, Nasal polyposis, Chronic rhinitis, Sinusitis OMIM:242670
Johnson Neuroectodermal Syndrome
Anosmia, Choanal atresia, Bulbous nose ORPHA:2316
Huntington Disease
Abnormality of the sense of smell ORPHA:399
Hypogonadotropic Hypogonadism 12 With Or Without Anosmia
Anosmia OMIM:614841
Refsum Disease, Classic
Anosmia OMIM:266500
Ciliary Dyskinesia, Primary, 30
Bronchiectasis, Nasal congestion, Nasal polyposis, Absent outer dynein arms, Recurrent respirator... OMIM:616037
Ciliary Dyskinesia, Primary, 22
Bronchiectasis, Nasal polyposis, Recurrent sinusitis, Absent inner and outer dynein arms, Recurre... OMIM:615444
Hydrolethalus
Abnormality of the sense of smell, Tracheal atresia, Laryngomalacia ORPHA:2189
Hypogonadotropic Hypogonadism 1 With Or Without Anosmia
Anosmia, Hyposmia, Azoospermia OMIM:308700
Neuropathy, Hereditary Motor And Sensory, Type Via, With Optic Atrophy
Anosmia OMIM:601152
Ichthyosis And Male Hypogonadism
Anosmia OMIM:308200
Johnson Neuroectodermal Syndrome
Anosmia, Choanal stenosis OMIM:147770
Immunodeficiency 13
Bronchiectasis, Recurrent upper respiratory tract infections, Nasal polyposis, Recurrent sinusiti... OMIM:615518
Ciliary Dyskinesia, Primary, 19
Bronchiectasis, Nasal polyposis, Recurrent sinusitis, Absent inner and outer dynein arms, Recurre... OMIM:614935
Kufor-Rakeb Syndrome
Anosmia, Hyposmia OMIM:606693
Campomelic Dysplasia
Tracheomalacia, Laryngomalacia, Tracheobronchomalacia, Abnormality of the sense of smell, Depress... ORPHA:140
Ciliary Dyskinesia, Primary, 15
Chronic sinusitis, Bronchiectasis, Nasal polyposis, Abnormal axonemal organization of respiratory... OMIM:613808
Kallmann Syndrome With Spastic Paraplegia
Anosmia OMIM:308750
8Q21.11 Microdeletion Syndrome
Abnormality of the sense of smell, Underdeveloped nasal alae, Wide nose ORPHA:284160
Ciliary Dyskinesia, Primary, 2
Bronchiectasis, Nasal polyposis, Absent inner and outer dynein arms, Sinusitis, Recurrent respira... OMIM:606763
Refsum Disease
Anosmia ORPHA:773
Acro-Renal-Mandibular Syndrome
Abnormality of the sense of smell, Tracheoesophageal fistula, Pulmonary hypoplasia, Abnormal lung... ORPHA:958
Congenital Hypothyroidism
Sinusitis, Anosmia, Tracheoesophageal fistula, Depressed nasal ridge ORPHA:442
Cleft, Median, Of Upper Lip With Polyps Of Facial Skin And Nasal Mucosa
Nasal polyposis OMIM:155145
Hyposmia-Nasal And Ocular Hypoplasia-Hypogonadotropic Hypogonadism Syndrome
Anosmia, Single naris, Hyposmia, Absent nares ORPHA:2250
Pai Syndrome
Nasal polyposis, Depressed nasal bridge, Midline defect of the nose ORPHA:1993
Septo-Optic Dysplasia Spectrum
Anosmia, Tracheoesophageal fistula ORPHA:3157
Kallmann Syndrome-Heart Disease Syndrome
Total anosmia, Partial anosmia, Pulmonary artery hypoplasia ORPHA:2326
Waardenburg Syndrome, Type 4C
Anosmia OMIM:613266
Young-Onset Parkinson Disease
Hyposmia ORPHA:2828
8P11.2 Deletion Syndrome
Anosmia, Azoospermia, Depressed nasal bridge ORPHA:251066
Kallmann Syndrome
Anosmia, Hyposmia ORPHA:478
Moebius Syndrome
Abnormality of the sense of smell ORPHA:570
Bosma Arhinia Microphthalmia Syndrome
Aplasia of the nose, Anosmia, Choanal atresia, Paranasal sinus hypoplasia OMIM:603457
Holoprosencephaly
Depressed nasal tip, Anosmia, Choanal atresia, Hyposmia, Aplasia/Hypoplasia of the lungs, Depress... ORPHA:2162
Waardenburg Syndrome, Type 2E
Anosmia OMIM:611584
Peripheral Demyelinating Neuropathy, Central Dysmyelination, Waardenburg Syndrome, And Hirschsprung Disease
Anosmia OMIM:609136
Hereditary Late-Onset Parkinson Disease
Hyposmia ORPHA:411602
Superficial Siderosis
Anosmia, Partial anosmia ORPHA:247245
Amoebiasis Due To Free-Living Amoebae
Respiratory tract infection, Hyposmia, Pneumonia, Sinusitis ORPHA:68
Primary Ciliary Dyskinesia
Abnormal sputum, Anomalous pulmonary venous return, Respiratory tract infection, Bronchiectasis, ... ORPHA:244
Lipoid Proteinosis
Nasal polyposis, Recurrent respiratory infections ORPHA:530
Leopard Syndrome 1
Hyposmia, Depressed nasal ridge OMIM:151100
Meningioma
Abnormality of the sense of smell ORPHA:2495
Intellectual Developmental Disorder With Impaired Language And Dysmorphic Facies
Hyposmia OMIM:618653
Occipital Horn Syndrome
Abnormality of the sense of smell ORPHA:198
Peutz-Jeghers Syndrome
Neoplasm of the nose, Nasal polyposis, Abnormality of the nose, Neoplasm of the lung ORPHA:2869
Charge Syndrome
Anosmia, Choanal atresia, Laryngomalacia, Tracheoesophageal fistula, Depressed nasal bridge ORPHA:138
Lacrimoauriculodentodigital Syndrome
Anosmia, Choanal atresia, Hypoplasia of the epiglottis ORPHA:2363
Eosinophilic Granulomatosis With Polyangiitis
Abnormal pleura morphology, Nasal polyposis, Recurrent intrapulmonary hemorrhage, Sinusitis, Hemo... ORPHA:183
Benign Schwannoma
Nasal polyposis, Abnormality of the larynx ORPHA:252164
Charge Syndrome
Anosmia, Choanal atresia, Tracheoesophageal fistula, Posterior choanal atresia OMIM:214800
Peutz-Jeghers Syndrome
Nasal polyposis OMIM:175200
Cystic Fibrosis
Chronic sinusitis, Bronchiectasis, Nasal polyposis, Recurrent bronchopulmonary infections, Recurr... OMIM:219700
Sarcoidosis
Abnormal lung morphology, Bronchiectasis, Pulmonary fibrosis, Abnormal pleura morphology, Emphyse... ORPHA:797

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Gfy

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Gfy.

No publications found that use IMPC mice or data for Gfy.

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