Gene Summary

Name:
zyg-ll family member B, cell cycle regulator
Synonyms:
LOC242610,  2810482G21Rik,  1110046I03Rik,  D4Mgi23

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Zyg11bem1(IMPC)J HET   Early adult 1.30×10-05
decreased thigmotaxis Zyg11bem1(IMPC)J HET   Early adult 1.30×10-05
preweaning lethality, incomplete penetrance Zyg11bem1(IMPC)J HOM   Early adult 0.00
hypoactivity Zyg11bem1(IMPC)J HET   Early adult 2.76×10-07
decreased body length Zyg11bem1(IMPC)J HET Early adult 6.45×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Electrocardiogram (ECG)

Waveform Image

16 Images

Human diseases caused by Zyg11b mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Zyg11b

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Zyg11b.

No publications found that use IMPC mice or data for Zyg11b.

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MGI Allele Allele Type Produced
Zyg11btm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Zyg11btm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Zyg11bem1(IMPC)J Exon Deletion Mice

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