Gene Summary

Name:
olfactomedin 4
Synonyms:
GC1,  LOC380924,  pPD4,  GW112,  LOC239192,  OlfD

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Olfm4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Olfm4 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Agammaglobulinemia 3, Autosomal Recessive
Recurrent bacterial infections, Diarrhea, Recurrent bronchitis, Recurrent otitis media, Agammaglo... OMIM:613501
Immunodeficiency 61
Malabsorption, Frequent Giardia lamblia infestation, Recurrent bacterial infections, Arthritis, R... OMIM:300310
Mannose-Binding Lectin Deficiency
Recurrent skin infections, Recurrent Klebsiella infections, Recurrent meningococcal disease, Diss... OMIM:614372
Immunodeficiency, Common Variable, 5
Recurrent bacterial infections, Chronic decreased circulating total IgG, Recurrent respiratory in... OMIM:613495
Immunodeficiency, Partial Combined, With Absence Of Hla Determinants And Beta-2-Microglobulin From Lymphocytes
Recurrent candida infections, Recurrent bacterial infections, Decreased circulating IgG level OMIM:242870
Immunodeficiency, Common Variable, 12, With Autoimmunity
Recurrent skin infections, Recurrent sinusitis, Decreased circulating antibody level, Recurrent p... OMIM:616576
Immunodeficiency 57 With Autoinflammation
Gastritis, Skin rash, Diarrhea, Inflammation of the large intestine, Decreased circulating antibo... OMIM:618108
Gastritis, Familial Giant Hypertrophic
Giant hypertrophic gastritis, Hypoproteinemia OMIM:137280
Immunodeficiency, Common Variable, 4
Decreased circulating IgG level, Decreased circulating total IgM, Recurrent bacterial infections,... OMIM:613494
Complement Component 7 Deficiency
Recurrent meningococcal disease, Recurrent Neisserial infections OMIM:610102
Immunodeficiency 35
Recurrent mycobacterial infections, Recurrent fungal infections, Recurrent viral infections, Incr... OMIM:611521
Ménétrier Disease
Abnormal gastric mucosa morphology, Gastroesophageal reflux, Multiple gastric polyps, Hypoprotein... ORPHA:2494
Immunodeficiency 51
Chronic furunculosis, Chronic oral candidiasis, Folliculitis, Recurrent cutaneous fungal infectio... OMIM:613953
Ficolin 3 Deficiency
Recurrent lower respiratory tract infections, Necrotizing enterocolitis, Recurrent abscess format... OMIM:613860
Inflammatory Bowel Disease (Crohn Disease) 30
Bloody diarrhea, Ileitis, Gastritis, Pancolitis, Vomiting, Protein-losing enteropathy, Chronic di... OMIM:619079
Immunodeficiency With Hyper-Igm, Type 2
Decreased circulating IgA level, Recurrent upper and lower respiratory tract infections, Recurren... OMIM:605258
Immune Dysregulation With Autoimmunity, Immunodeficiency, And Lymphoproliferation
Crohn's disease, Decreased circulating IgA level, Decreased circulating IgG level, Decreased circ... OMIM:616100
Immunodeficiency, X-Linked, With Deficiency Of 115,000 Dalton Surface Glycoprotein
Recurrent protozoan infections, Recurrent viral infections, Recurrent bacterial infections OMIM:308220
Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Il12Rb1 Deficiency
Recurrent candida infections, Recurrent mycobacterial infections, Histoplasmosis, Severe toxoplas... ORPHA:319552
Immunodeficiency 34
Recurrent mycobacterial infections, Severe recurrent varicella OMIM:300645
Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency
Chronic gastritis, Rheumatoid arthritis, Sepsis, Epididymitis, Chronic sinusitis, Pneumonia, Decr... ORPHA:183675
Immunodeficiency 30
Recurrent mycobacterial infections, Recurrent infections OMIM:614891
Diffuse Gastric And Lobular Breast Cancer Syndrome
Atrophic gastritis, Cleft palate, Stomach cancer OMIM:137215
Agammaglobulinemia 2, Autosomal Recessive
Decreased circulating IgA level, Recurrent bacterial infections, Decreased circulating total IgM,... OMIM:613500
Immunodeficiency, Common Variable, 3
Decreased circulating IgA level, Reduced isohemagglutinin level, Recurrent bacterial infections, ... OMIM:613493
Agammaglobulinemia 6, Autosomal Recessive
Decreased circulating IgA level, Decreased circulating IgG level, Recurrent bacterial infections,... OMIM:612692
Immunoglobulin Kappa Light Chain Deficiency
Diarrhea, Abnormal immunoglobulin level, Recurrent infections OMIM:614102
Agammaglobulinemia 4, Autosomal Recessive
Decreased circulating IgA level, Decreased circulating IgG level, Decreased circulating total IgM... OMIM:613502
Complement Factor D Deficiency
Recurrent bacterial infections OMIM:613912
Immunodeficiency Due To Interleukin-1 Receptor-Associated Kinase-4 Deficiency
Recurrent bacterial infections, Recurrent streptococcus pneumoniae infections, Recurrent staphylo... ORPHA:70592
Complement Component 8 Deficiency, Type Ii
Meningitis, Recurrent Neisserial infections OMIM:613789
Leukoencephalopathy, Arthritis, Colitis, And Hypogammaglobulinema
Chronic gastritis, Colitis, Decreased circulating IgG level, Eczema, Diarrhea, Inflammation of th... OMIM:608809
Neutropenia, Severe Congenital, 6, Autosomal Recessive
Recurrent bacterial infections, Recurrent respiratory infections, Recurrent otitis media OMIM:616022
Immunodeficiency With Hyper-Igm, Type 5
Decreased circulating IgA level, Recurrent upper and lower respiratory tract infections, Decrease... OMIM:608106
Complement Component 6 Deficiency
Recurrent meningococcal disease OMIM:612446
Bare Lymphocyte Syndrome, Type Ii
Recurrent protozoan infections, Malabsorption, Recurrent fungal infections, Colitis, Viral hepati... OMIM:209920
Myelolymphatic Insufficiency
Recurrent viral infections, Recurrent bacterial infections OMIM:310350
Immunodeficiency 31B
Recurrent mycobacterial infections, Recurrent viral infections, Herpes simplex encephalitis OMIM:613796
Immunodeficiency 12
Recurrent viral infections, Recurrent bacterial infections OMIM:615468
Immune Deficiency Disease
Recurrent bacterial infections, Decreased circulating total IgM, Fulminant hepatitis, Cholangitis... OMIM:242850
Immunodeficiency 28
Recurrent mycobacterial infections OMIM:614889
Neutrophil Actin Dysfunction
Recurrent bacterial infections OMIM:257150
Immunodeficiency, Common Variable, 8, With Autoimmunity
Sepsis, Decreased specific antibody response to vaccination, Uveitis, Pneumonia, Decreased circul... OMIM:614700
Severe Combined Immunodeficiency Due To Dclre1C Deficiency
Recurrent mycobacterial infections, Recurrent gastroenteritis, Decreased circulating IgA level, R... ORPHA:275
Complement Factor B Deficiency
Recurrent bacterial infections, Peritonitis, Recurrent meningococcal disease, Meningitis, Pneumonia OMIM:615561
Cd8 Deficiency, Familial
Bronchiectasis, Recurrent viral infections, Recurrent bacterial infections, Recurrent respiratory... OMIM:608957
Immune Dysregulation-Polyendocrinopathy-Enteropathy-X-Linked Syndrome
Recurrent gastroenteritis, Gastritis, Sepsis, Eczema, Decreased prealbumin level, Vomiting, Pneum... ORPHA:37042
Cap Polyposis
Constipation, Diarrhea, Hematochezia, Colorectal polyposis, Atrophic gastritis ORPHA:160148
Immunodeficiency 33
Increased circulating IgA level, Recurrent bacterial infections, Decreased circulating total IgM,... OMIM:300636
Immunodeficiency, Common Variable, 2
Decreased circulating IgA level, Decreased circulating IgG level, Partial absence of specific ant... OMIM:240500
Immunodeficiency 84
Recurrent bacterial infections, Perianal abscess, Persistent EBV viremia OMIM:619437
T-Cell Immunodeficiency, Recurrent Infections, And Autoimmunity With Or Without Cardiac Malformations
Recurrent viral infections, Recurrent bacterial infections, Recurrent fungal infections OMIM:614868
Immunodeficiency, Common Variable, 1
Decreased circulating IgA level, Decreased circulating IgG level, Decreased circulating total IgM... OMIM:607594
Immunodeficiency 38 With Basal Ganglia Calcification
Recurrent mycobacterial infections OMIM:616126
Hyper-Ige Recurrent Infection Syndrome 2, Autosomal Recessive
Recurrent fungal infections, Eosinophilic infiltration of the esophagus, Decreased circulating to... OMIM:243700
Whim Syndrome 1
Decreased circulating IgG level, Recurrent bacterial infections, Recurrent upper respiratory trac... OMIM:193670
Autoinflammatory Syndrome, Familial, X-Linked, Behcet-Like 2
Increased circulating interleukin 6 concentration, Chronic gastritis, Colitis, Elevated circulati... OMIM:301074
Immunodeficiency By Defective Expression Of Mhc Class Ii
Recurrent protozoan infections, Recurrent infection of the gastrointestinal tract, Chronic hepati... ORPHA:572
Complement Component 3 Deficiency, Autosomal Recessive
Recurrent bacterial infections, Membranoproliferative glomerulonephritis, Recurrent pneumonia, Re... OMIM:613779
Immunodeficiency With Hyper-Igm, Type 3
Decreased circulating IgA level, Decreased circulating IgG level, Recurrent bacterial infections,... OMIM:606843
Cystic Fibrosis-Gastritis-Megaloblastic Anemia Syndrome
Diarrhea, Gastritis, Recurrent respiratory infections ORPHA:2575
Leukocyte Adhesion Deficiency, Type I
Periodontitis, Osteomyelitis, Elevated circulating C-reactive protein concentration, Recurrent ba... OMIM:116920
Thymic Aplasia
Recurrent streptococcus pneumoniae infections, Recurrent infection of the gastrointestinal tract,... ORPHA:83471
Isolated Growth Hormone Deficiency, Type Iii, With Agammaglobulinemia
Sinusitis, Prostatitis, Enteroviral dermatomyositis syndrome, Pyoderma, Enteroviral hepatitis, Re... OMIM:307200
Agammaglobulinemia 1, Autosomal Recessive
Bronchiectasis, Recurrent bacterial infections, Panhypogammaglobulinemia, Recurrent sinusitis, De... OMIM:601495
Immunodeficiency 27B
Recurrent mycobacterial infections, Salmonella osteomyelitis, Recurrent mycobacterium avium compl... OMIM:615978
Immunodeficiency 82 With Systemic Inflammation
Elevated circulating C-reactive protein concentration, Gastritis, Diarrhea, Vomiting, Pneumonia, ... OMIM:619381
Adult Idiopathic Neutropenia
Recurrent fungal infections, Recurrent bacterial infections, Helicobacter pylori infection, Recur... ORPHA:2688
T-B+ Severe Combined Immunodeficiency Due To Gamma Chain Deficiency
Decreased circulating IgA level, Recurrent bacterial skin infections, Decreased circulating IgG l... ORPHA:276
Selective Igm Deficiency
Keratitis, Onychomycosis, Recurrent infection of the gastrointestinal tract, Otitis media, Stomac... ORPHA:331235
Complement Component 5 Deficiency
Recurrent meningococcal disease, Intractable diarrhea, Generalized seborrheic dermatitis, Recurre... OMIM:609536
Cernunnos-Xlf Deficiency
Recurrent viral infections, Recurrent bacterial infections, Decreased circulating antibody level ORPHA:169079
Immunodeficiency, Common Variable, 6
Decreased specific pneumococcal antibody level, Recurrent bacterial infections, Chronic decreased... OMIM:613496
Retinitis Pigmentosa, X-Linked, And Sinorespiratory Infections, With Or Without Deafness
Recurrent bronchitis, Chronic sinusitis, Recurrent Haemophilus influenzae infections, Otitis media OMIM:300455
Immunodeficiency With Hyper-Igm, Type 4
Osteomyelitis, Recurrent infection of the gastrointestinal tract, Recurrent bacterial infections,... OMIM:608184
Immunodeficiency, Common Variable, 13
Recurrent bacterial infections, Decreased circulating antibody level OMIM:616873
Mixed Connective Tissue Disease
Gastroesophageal reflux, Gastritis, Skin rash, Xerostomia, Myositis, Myocarditis, Arthritis, Kera... ORPHA:809
Hyper-Ige Recurrent Infection Syndrome 1, Autosomal Dominant
High palate, Cutaneous abscess, Recurrent fungal infections, Eczematoid dermatitis, Skin rash, Ch... OMIM:147060
Zygomycosis
Melena, Gastritis, Pancreatitis, Unusual gastrointestinal infection, Diarrhea, Vomiting, Acute in... ORPHA:73263
Granulomatous disease with defect in neutrophil chemotaxis
Recurrent staphylococcal infections OMIM:233670
Omenn Syndrome
Recurrent fungal infections, Hypoproteinemia, Recurrent bacterial infections, Diarrhea, Pneumonia... OMIM:603554
Agammaglobulinemia 9, Autosomal Recessive
Agammaglobulinemia, Recurrent bacterial infections, Eczematoid dermatitis, Seborrheic dermatitis OMIM:619693
Combined Immunodeficiency Due To Zap70 Deficiency
Recurrent mycobacterial infections, Recurrent upper and lower respiratory tract infections, Recur... ORPHA:911
Autoimmune Polyendocrine Syndrome, Type I, With Or Without Reversible Metaphyseal Dysplasia
Iridocyclitis, Chronic active hepatitis, Chronic oral candidiasis, Malabsorption, Diarrhea, Kerat... OMIM:240300
Immunodeficiency 67
Increased circulating IgE level, Recurrent streptococcal infections, Recurrent staphylococcal inf... OMIM:607676
Polyposis of gastric fundus without polyposis coli
Abnormal gastric mucosa morphology, Multiple gastric polyps OMIM:175505
Immunodeficiency 87 And Autoimmunity
Hypokalemia, Elevated circulating C-reactive protein concentration, Recurrent fungal infections, ... OMIM:619573
Immunodeficiency 36
Decreased circulating IgA level, Decreased circulating IgG level, Recurrent bacterial infections,... OMIM:616005
Immunodeficiency With Hyper-Igm, Type 1
Decreased circulating IgA level, Decreased circulating IgG level, Increased circulating IgA level... OMIM:308230
Proteasome-Associated Autoinflammatory Syndrome 2
Increased circulating IgA level, Elevated circulating C-reactive protein concentration, Skin rash... OMIM:618048
Complement Factor H Deficiency
Recurrent bacterial infections OMIM:609814
Autoimmune Lymphoproliferative Syndrome
Decreased specific anti-polysaccharide antibody level, Increased circulating antibody level, Coli... ORPHA:3261
Griscelli Syndrome, Type 2
Recurrent bacterial infections OMIM:607624
Neutropenia, Severe Congenital, 1, Autosomal Dominant
Increased circulating antibody level, Recurrent bacterial infections OMIM:202700
Immunodeficiency 41 With Lymphoproliferation And Autoimmunity
Decreased specific anti-polysaccharide antibody level, Thyroiditis, Decreased circulating IgA lev... OMIM:606367
Syndromic Diarrhea
Bloody diarrhea, Colitis, Gastritis, Intractable diarrhea, Hepatoblastoma, Panhypogammaglobulinem... ORPHA:84064
Complement Factor I Deficiency
Recurrent streptococcus pneumoniae infections, Recurrent skin infections, Recurrent urinary tract... OMIM:610984
Aicardi-Goutieres Syndrome 7
Increased circulating ferritin concentration, Increased circulating antibody level, Bloody diarrh... OMIM:615846
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency
Decreased circulating IgA level, Recurrent upper and lower respiratory tract infections, Decrease... ORPHA:331206
Autoimmune Polyendocrinopathy Type 4
Iridocyclitis, Rheumatoid arthritis, Xerostomia, Hepatitis, Tubulointerstitial nephritis, Decreas... ORPHA:227990
Autoimmune Polyendocrinopathy Type 3
Iridocyclitis, Rheumatoid arthritis, Xerostomia, Hepatitis, Tubulointerstitial nephritis, Decreas... ORPHA:227982
Granulomatous Disease, Chronic, Autosomal Recessive, 1
Discoid lupus rash, Recurrent bacterial skin infections, Eczematoid dermatitis, Osteomyelitis, Ly... OMIM:233700
Granulomatous Disease, Chronic, Autosomal Recessive, 2
Discoid lupus rash, Recurrent bacterial skin infections, Eczematoid dermatitis, Osteomyelitis, Ly... OMIM:233710
Autosomal Dominant Severe Congenital Neutropenia
Periodontitis, Recurrent infection of the gastrointestinal tract, Rhinitis, Recurrent skin infect... ORPHA:486
Neutropenia, Severe Congenital, X-Linked
Recurrent bacterial infections, Eczema OMIM:300299
Granulomatous Disease, Chronic, Autosomal Recessive, 4
Discoid lupus rash, Recurrent bacterial skin infections, Eczematoid dermatitis, Osteomyelitis, Ly... OMIM:233690
Specific Granule Deficiency 1
Recurrent bacterial infections OMIM:245480
Ethylene Glycol Poisoning
Hypocalcemia, Gastritis, Vomiting, Nausea, Hyperkalemia ORPHA:31826
Pgm3-Cdg
High palate, Sepsis, Eczema, Chronic sinusitis, Recurrent viral infections, Lactose intolerance, ... ORPHA:443811
Purine Nucleoside Phosphorylase Deficiency
Sinusitis, Otitis media, Increased circulating inosine concentration, Recurrent bacterial infecti... OMIM:613179
Combined Immunodeficiency Due To Crac Channel Dysfunction
Recurrent mycobacterial infections, Recurrent fungal infections, Sepsis, Recurrent bacterial infe... ORPHA:169090
Postinfectious Vasculitis
Recurrent streptococcus pneumoniae infections, Elevated circulating C-reactive protein concentrat... ORPHA:48435
Ectodermal Dysplasia And Immunodeficiency 1
Increased circulating IgA level, Abnormal circulating IgG level, Recurrent bacterial infections, ... OMIM:300291
Cystic Fibrosis With Helicobacter Pylori Gastritis, Megaloblastic Anemia, And Mental Retardation
Exocrine pancreatic insufficiency, Recurrent bronchopulmonary infections, Gastritis, Meconium ile... OMIM:219721
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Negative, Due To Adenosine Deaminase Deficiency
Decreased circulating IgA level, Recurrent fungal infections, Inflammatory abnormality of the ski... OMIM:102700
Specific Granule Deficiency 2
Intractable diarrhea, Recurrent bacterial infections, Sepsis, Recurrent pneumonia, Recurrent otit... OMIM:617475
Immunodeficiency 23
High palate, Eczema, Membranoproliferative glomerulonephritis, Increased circulating IgG level, S... OMIM:615816
X-Linked Severe Congenital Neutropenia
Recurrent bacterial infections ORPHA:86788
Neutropenia, Severe Congenital, 3, Autosomal Recessive
Recurrent bacterial infections OMIM:610738
Whim Syndrome
Sinusitis, Otitis media, Sepsis, Recurrent bacterial infections, Recurrent upper respiratory trac... ORPHA:51636
Liver Disease, Severe Congenital
Increased circulating ferritin concentration, Chronic gastritis, Recurrent otitis media, Hypocalc... OMIM:619991
Nk-Cell Enteropathy
Abnormal gastric mucosa morphology, Constipation, Gastroesophageal reflux, Intestinal polyp, Diar... ORPHA:263665
Combined Immunodeficiency With Faciooculoskeletal Anomalies
Recurrent fungal infections, Chronic oral candidiasis, Gastroesophageal reflux, Decreased circula... ORPHA:221139
Polyglucosan Body Myopathy 1 With Or Without Immunodeficiency
Hypoproteinemia, Recurrent bacterial infections, Elevated circulating creatine kinase concentrati... OMIM:615895
Hypocomplementemic Urticarial Vasculitis
Skin rash, Recurrent bacterial infections, Diarrhea, Arthritis, Meningitis, Uveitis, Episcleritis... ORPHA:36412
Mirage Syndrome
Gastroesophageal reflux, Aspiration pneumonia, Recurrent bacterial infections, Sepsis, Recurrent ... OMIM:617053
Granulomatous Disease, Chronic, X-Linked
Discoid lupus rash, Recurrent bacterial skin infections, Eczematoid dermatitis, Osteomyelitis, Ly... OMIM:306400
Immunodeficiency 21
Recurrent viral infections, Recurrent mycobacterium avium complex infections, Recurrent fungal in... OMIM:614172
Leukocyte Adhesion Deficiency, Type Iii
Recurrent bacterial infections, Recurrent skin infections, Sepsis OMIM:612840
Idiopathic Bronchiectasis
Recurrent lower respiratory tract infections, Acute infectious pneumonia, Recurrent Haemophilus i... ORPHA:60033
Immunodeficiency 10
Recurrent bacterial infections, Recurrent infections OMIM:612783
Oculogastrointestinal Muscular Dystrophy
Malabsorption, Abnormal gastric mucosa morphology, Abnormality of the gastrointestinal tract, Spo... ORPHA:1876
Vici Syndrome
Recurrent fungal infections, Decreased circulating IgG level, Cleft palate, Recurrent bacterial i... OMIM:242840
Hypoparathyroidism-Retardation-Dysmorphism Syndrome
Hypocalcemia, Recurrent bacterial infections, Bifid uvula, Hyperphosphatemia, Hypocalcemic seizures OMIM:241410
Viss Syndrome
High palate, Chronic gastritis, Eczema, Broad uvula, Decreased circulating IgA level, High, narro... OMIM:619472
Immunodeficiency 47
Exocrine pancreatic insufficiency, Decreased circulating total IgA, Decreased circulating total I... OMIM:300972
Leukocyte Adhesion Deficiency
Otitis media, Sepsis, Severe periodontitis, Pneumonia, BCGosis, Osteomyelitis, Recurrent tonsilli... ORPHA:2968
Kenny-Caffey Syndrome, Type 1
Recurrent bacterial infections, Hypomagnesemia, Hypocalcemia OMIM:244460
Lysinuric Protein Intolerance
Increased circulating ferritin concentration, Pancreatitis, Steatorrhea, Diarrhea, Intraalveolar ... ORPHA:470
Chédiak-Higashi Syndrome
Increased circulating ferritin concentration, Recurrent bacterial skin infections, Periodontitis,... ORPHA:167
Trichorhinophalangeal Syndrome, Type Ii
Chronic gastritis, Gastroesophageal reflux, Recurrent upper respiratory tract infections, Vomitin... OMIM:150230
Glycogen Storage Disease Ib
Hyperlipidemia, Pancreatitis, Recurrent bacterial infections, Hepatocellular carcinoma, Gout, Inf... OMIM:232220
Dubin-Johnson Syndrome
Abnormal gastric mucosa morphology, Conjugated hyperbilirubinemia ORPHA:234
Shwachman-Diamond Syndrome
Exocrine pancreatic insufficiency, Osteomyelitis, Hypoamylasemia, Sinusitis, Skin rash, Steatorrh... ORPHA:811
Congenital Disorder Of Glycosylation, Type Iif
Recurrent bacterial infections OMIM:603585
Infantile Systemic Hyalinosis
Malabsorption, Steatorrhea, Recurrent bacterial infections, Abnormality of the gastrointestinal t... ORPHA:2176
Reynolds Syndrome
Abnormal gastric mucosa morphology, Gastroesophageal reflux, Skin rash, Xerostomia, Arthritis, In... ORPHA:779
Neutropenia, Severe Congenital, 4, Autosomal Recessive
High palate, Cleft palate, Otitis media, Sepsis, Recurrent urinary tract infections, Recurrent ba... OMIM:612541
Primary Ciliary Dyskinesia
Recurrent mycobacterial infections, Intestinal malrotation, Chronic otitis media, Chronic rhiniti... ORPHA:244
Hermansky-Pudlak Syndrome 2
Periodontitis, Chronic oral candidiasis, Gastroesophageal reflux, Recurrent bacterial infections,... OMIM:608233
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib
Periodontitis, Hyperlipidemia, Pancreatitis, Enterocolitis, Recurrent bacterial infections, Diarr... ORPHA:79259
Mannosidosis, Alpha B, Lysosomal
Recurrent bacterial infections, Decreased circulating antibody level, Macroglossia OMIM:248500
Chromomycosis
Keratitis, Recurrent bacterial infections, Keratoconjunctivitis sicca ORPHA:182
Chediak-Higashi Syndrome
Recurrent bacterial skin infections, Recurrent systemic pyogenic infections, Periodontitis, Recur... OMIM:214500
Sickle Cell Anemia
Recurrent bacterial infections OMIM:603903
Ichthyosis Follicularis-Alopecia-Photophobia Syndrome
Keratitis, Blepharitis, Cheilitis, Recurrent bacterial infections, Eczema, Uveitis, Recurrent inf... ORPHA:2273
Atrial Septal Defect, Coronary Sinus Type
Recurrent bacterial infections, Pneumonia ORPHA:99104
Atrial Septal Defect, Ostium Secundum Type
Recurrent bacterial infections, Pneumonia ORPHA:99103
Williams Syndrome
Abnormal gastric mucosa morphology, Malabsorption, Gastroesophageal reflux, Constipation, Macrogl... ORPHA:904
Hereditary Sensory And Autonomic Neuropathy Type 4
Osteomyelitis, Recurrent aspiration pneumonia, Fasciitis, Recurrent Staphylococcus aureus infecti... ORPHA:642

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Olfm4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Olfm4.

No publications found that use IMPC mice or data for Olfm4.

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MGI Allele Allele Type Produced
Olfm4tm428494(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Olfm4em2(IMPC)H Exon Deletion Mice
Olfm4tm237958(L1L2_Bact_P) Reporter-tagged deletion allele (with selection cassette) Targeting vectors
Olfm4em1(IMPC)H Exon Deletion Mice

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