IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- No Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Taar8a by phenotypic similarity.
|Retinal Dysplasia, Primary||
||Retinal dysplasia, Falciform retinal fold||OMIM:312550|
|Stargardt Disease 1||
||Retinitis pigmentosa inversa, Macular degeneration, Bull's eye maculopathy||OMIM:248200|
|Macular Degeneration, Age-Related, 15||
|Macular Degeneration, Age-Related, 2||
|Macular Degeneration, Age-Related, 11||
|Macular Degeneration, Age-Related, 6||
|Macular Degeneration, Age-Related, 4||
|Central Retinal Vein Occlusion||
||Macular edema, Retinal vascular tortuosity, Macular degeneration, Epiretinal membrane, Retinal ne...||ORPHA:411527|
|Vitreoretinopathy, Neovascular Inflammatory||
||Large hyperpigmented retinal spots, Posterior retinal neovascularization, Vitreous hemorrhage, Pe...||OMIM:193235|
|Exudative Vitreoretinopathy 2, X-Linked||
||Exudative vitreoretinopathy, Intraretinal exudate, Retinal fold, Retinal hole, Falciform retinal ...||OMIM:305390|
|Exudative Vitreoretinopathy 1||
||Exudative vitreoretinopathy, Vitreous hemorrhage, Falciform retinal fold, Posterior vitreous deta...||OMIM:133780|
|Familial Exudative Vitreoretinopathy||
||Macular exudate, Vitreous hemorrhage, Tractional retinal detachment, Macular edema, Falciform ret...||ORPHA:891|
|Reese Retinal Dysplasia||
||Retinal dysplasia, Remnants of the hyaloid vascular system||OMIM:266400|
||Vitreous hemorrhage, Tractional retinal detachment, Macular edema, Vitreous haze, Vitritis, Retin...||ORPHA:40923|
||Retinal arteriolar constriction, Vitreous hemorrhage, Retinal arteriolar occlusion, Abnormality o...||OMIM:193220|
|Cleft Palate, Proliferative Retinopathy, And Developmental Delay||
|Retinal Vasculopathy With Cerebral Leukoencephalopathy And Systemic Manifestations||
||Retinal neovascularization, Retinal cotton wool spot, Macular edema, Abnormal retinal vascular mo...||ORPHA:247691|
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|MGI Allele||Allele Type||Produced|
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