Mboat4 | membrane bound O-acyltransferase domain containing 4

GeneMGI:2685017Synonyms: GOAT, LOC234155

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Vision/eye

17 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal retina inner nuclear layer morphology1 supporting datasetMboat4tm2b(EUCOMM)HmguhomozygoteEarly adult9.78x10-5 
abnormal retina outer nuclear layer morphology2 supporting datasetsMboat4tm2b(EUCOMM)HmguhomozygoteEarly adult7x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/2)0.7% (4/570)
aortaheterozygoten/a0% (0/2)0.19% (1/533)
boneheterozygoten/a0% (0/2)0% (0/394)
brainheterozygoten/a0% (0/2)0.86% (5/579)
brainstemheterozygoten/a0% (0/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cecumheterozygoten/a0% (0/1)7.75% (22/284)
cerebellumheterozygoten/a0% (0/2)0.56% (3/532)
cerebral cortexheterozygoten/a0% (0/2)0.41% (2/491)
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Histopathology

IMPC related publications

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Mboat4tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Mboat4tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Mboat4tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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