Gene: Cenpj

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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased T cell number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 7.11×10-09
increased NK cell number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.79×10-05
abnormal behavior Cenpjtm1a(EUCOMM)Wtsi HET postnatal 7.09×10-05
abnormal tail morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 5.05×10-13
abnormal humerus morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.57×10-12
abnormal cranium morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.28×10-09
abnormal vertebrae morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 3.56×10-08
abnormal ulna morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 7.00×10-06
hypoactivity Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 2.30×10-08
increased sacral vertebrae number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.53×10-07
vertebral fusion Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 7.19×10-07
decreased lean body mass Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 4.82×10-26
decreased caudal vertebrae number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 5.53×10-06
decreased body weight Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.15×10-30
decreased circulating calcium level Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.57×10-05
abnormal external male genitalia morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 2.64×10-08
abnormal head morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 3.43×10-10
decreased monocyte cell number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 4.36×10-06
decreased circulating serum albumin level Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 3.93×10-07
decreased body length Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 2.19×10-19
abnormal joint morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 7.22×10-12
abnormal tail movements Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 8.77×10-08
decreased bone mineral content Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.52×10-16
abnormal external female genitalia morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 5.87×10-07
abnormal femur morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 6.96×10-06
abnormal tibia morphology Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.61×10-10
decreased circulating total protein level Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 8.02×10-11
abnormal behavior Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 2.37×10-13
increased CD8-positive, alpha-beta T cell number Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 5.07×10-09
decreased total body fat amount Cenpjtm1a(EUCOMM)Wtsi HOM postnatal 1.46×10-07

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IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584) N/A
Aorta 3 No N/A
Blood vessel 3 No N/A
Bone 3 No N/A
Brain 3 No  (3/3) N/A
Brainstem 3 No N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No N/A
Cerebellum 3 No N/A
Cerebral cortex 3 No N/A
Eye 3 No N/A
Gall bladder 3 No N/A
Heart 3 No N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Kidney 3 No  (18/584) N/A
Large intestine 3 No  (10/584) N/A
Liver 3 No N/A
Lower urinary tract 3 No N/A
Lung 3 No N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Esophagus 3 No N/A
Olfactory lobe 3 No N/A
Ovary 3 No  (1/584) N/A
Oviduct 3 No N/A
Pancreas 3 No  (5/584) N/A
Parathyroid gland 3 No N/A
Peripheral nervous system 3 No N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584) N/A
Skeletal muscle tissue 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/584) N/A
Spinal cord 3 No  (2/3) N/A
Spleen 3 No  (2/584) N/A
Stomach 3 No  (12/584) N/A
Striatum 3 No N/A
Testis 3 No  (2/584)  (1/3) N/A
Thymus 3 No N/A
Thyroid gland 3 No  (15/584) N/A
Trachea 3 No N/A
Uterus 3 No N/A
White adipose tissue 3 No N/A
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

Brain Histopathology: Striatal Section
2 Images
Brain Histopathology: Hippocampal section
3 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Cenpjtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cenpjtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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