Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Syna by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Hereditary Persistence Of Fetal Hemoglobin-Beta-Thalassemia Syndrome | Pallor | ORPHA:46532 | |
Methylmalonic Acidemia With Homocystinuria, Type Cbld | Pallor | ORPHA:79283 | |
Peripheral Cone Dystrophy | Pallor | OMIM:609021 | |
Cone-Rod Dystrophy 11 | Pallor | OMIM:610381 | |
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome | Short stature, Pallor | ORPHA:2786 | |
Dermatitis, Atopic | Dry skin, Facial erythema, Pallor | OMIM:603165 | |
Acute Peripheral Arterial Occlusion | Pallor | ORPHA:90064 | |
Benign Paroxysmal Torticollis Of Infancy | Pallor | ORPHA:71518 | |
Breath-Holding Spells | Pallor | OMIM:607578 | |
Leber Congenital Amaurosis 14 | Pallor | OMIM:613341 | |
Optic Atrophy 1 | Pallor | OMIM:165500 | |
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 2 | Growth delay, Pallor | OMIM:613561 | |
Acute Myelomonocytic Leukemia | Pallor | ORPHA:517 | |
Optic Atrophy 7 With Or Without Auditory Neuropathy | Pallor | OMIM:612989 | |
Hemoglobin D Disease | Pallor | ORPHA:90039 | |
Congenital Heart Block | Intrauterine growth retardation, Pallor, Patent ductus arteriosus | ORPHA:60041 | |
Familial Focal Epilepsy With Variable Foci | Pallor | ORPHA:98820 | |
Primary Lateral Sclerosis, Juvenile | Pallor | OMIM:606353 | |
X-Linked Sideroblastic Anemia | Pallor | ORPHA:75563 | |
Anemia, Congenital Dyserythropoietic, Type Ib | Short stature, Growth delay, Pallor | OMIM:615631 | |
Cyclic Vomiting Syndrome | Growth delay, Pallor | OMIM:500007 | |
Thiamine-Responsive Megaloblastic Anemia Syndrome | Short stature, Pallor | ORPHA:49827 | |
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome | Pallor | ORPHA:276608 | |
Spontaneous Periodic Hypothermia | Pallor | ORPHA:29822 | |
Retinitis Pigmentosa 51 | Pallor | OMIM:613464 | |
Evans Syndrome | Pallor, Petechiae | ORPHA:1959 | |
Hyperinsulinism Due To Ucp2 Deficiency | Pallor | ORPHA:276556 | |
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency | Pallor | ORPHA:276575 | |
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency | Pallor | ORPHA:276580 | |
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia | Short stature, Pallor | OMIM:611590 | |
Hyperinsulinism Due To Hnf1A Deficiency | Pallor | ORPHA:324575 | |
Beta-Thalassemia | Pallor, Skin ulcer | ORPHA:848 | |
Pyruvate Kinase Deficiency Of Red Cells | Intrauterine growth retardation, Pallor | OMIM:266200 | |
Leishmaniasis | Pallor, Skin ulcer | ORPHA:507 | |
Myopathic Ehlers-Danlos Syndrome | Pallor | ORPHA:536516 | |
Myopathy, Lactic Acidosis, And Sideroblastic Anemia 1 | Delayed puberty, Pallor, Growth delay | OMIM:600462 | |
Dravet Syndrome | Pallor | ORPHA:33069 | |
Fanconi Anemia, Complementation Group I | Short stature, Intrauterine growth retardation, Pallor | OMIM:609053 | |
Primary Myelofibrosis | Purpura, Petechiae, Pallor, Ecchymosis | ORPHA:824 | |
Irida Syndrome | Pallor | ORPHA:209981 | |
Anemia, Hypochromic Microcytic, With Iron Overload 2 | Growth delay, Pallor | OMIM:615234 | |
Kcnq2-Related Epileptic Encephalopathy | Facial erythema, Pallor | ORPHA:439218 | |
Non-Functioning Paraganglioma | Pallor | ORPHA:94080 | |
Hb Bart'S Hydrops Fetalis | Pallor | ORPHA:163596 | |
Megaloblastic Anemia Due To Dihydrofolate Reductase Deficiency | Pallor | OMIM:613839 | |
Drug-Induced Autoimmune Hemolytic Anemia | Pallor | ORPHA:90037 | |
Cold Agglutinin Disease | Pallor | ORPHA:56425 | |
Myelofibrosis | Purpura, Pallor | OMIM:254450 | |
Deafness-Lymphedema-Leukemia Syndrome | Pallor | ORPHA:3226 | |
Acquired Idiopathic Sideroblastic Anemia | Pallor | ORPHA:75564 | |
Retinitis Pigmentosa 75 | Pallor | OMIM:617023 | |
Mixed-Type Autoimmune Hemolytic Anemia | Pallor | ORPHA:90036 | |
Anemia, Sideroblastic, 1 | Anemic pallor | OMIM:300751 | |
Congenital Dyserythropoietic Anemia Type Iii | Short stature, Pallor | ORPHA:98870 | |
Anemia, Sideroblastic, And Spinocerebellar Ataxia | Short stature, Intrauterine growth retardation, Pallor | OMIM:301310 | |
6-Pyruvoyl-Tetrahydropterin Synthase Deficiency | Pallor | ORPHA:13 | |
Idiopathic Pulmonary Hemosiderosis | Pallor | ORPHA:99931 | |
Myopathy, Mitochondrial, And Ataxia | Short stature, Growth delay, Pallor | OMIM:617675 | |
Rheumatic Fever | Erythema, Pallor | ORPHA:3099 | |
Cone-Rod Dystrophy 8 | Pallor | OMIM:605549 | |
American Trypanosomiasis | Pallor | ORPHA:3386 | |
Tay-Sachs Disease | Pallor | OMIM:272800 | |
Congenital Hyperinsulinism Due To Hnf4A Deficiency | Pallor | ORPHA:263455 | |
Elliptocytosis 1 | Pallor | OMIM:611804 | |
Hereditary Spherocytosis | Growth delay, Skin ulcer, Pallor | ORPHA:822 | |
Autoimmune Hemolytic Anemia, Warm Type | Pallor | ORPHA:90033 | |
Dominant Beta-Thalassemia | Delayed puberty, Skin ulcer, Pallor, Growth delay | ORPHA:231226 | |
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts | Growth delay, Pallor | ORPHA:300298 | |
Senior-Loken Syndrome 8 | Pallor | OMIM:616307 | |
Plummer-Vinson Syndrome | Pallor | ORPHA:54028 | |
Childhood Absence Epilepsy | Pallor | ORPHA:64280 | |
Beta-Thalassemia Intermedia | Pallor, Skin ulcer | ORPHA:231222 | |
Sepsis In Premature Infants | Purpura, Petechiae, Pallor | ORPHA:90051 | |
Letterer-Siwe Disease | Pallor | OMIM:246400 | |
Hereditary Folate Malabsorption | Pallor | ORPHA:90045 | |
Fructose-1,6-Bisphosphatase Deficiency | Pallor | ORPHA:348 | |
Beta-Thalassemia Major | Delayed puberty, Skin ulcer, Pallor, Growth delay | ORPHA:231214 | |
Sporadic Pheochromocytoma/Secreting Paraganglioma | Pallor | ORPHA:276621 | |
Beta-Ketothiolase Deficiency | Pallor | ORPHA:134 | |
Waldenström Macroglobulinemia | Purpura, Pallor | ORPHA:33226 | |
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency | Pallor | OMIM:246450 | |
Severe Combined Immunodeficiency Due To Complete Rag1/2 Deficiency | Pallor | ORPHA:331206 | |
Imerslund-Gräsbeck Syndrome | Pallor | ORPHA:35858 | |
Non-Functioning Pituitary Adenoma | Pallor | ORPHA:91349 | |
Adenohypophysitis | Pallor | ORPHA:95512 | |
Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema | Pallor | OMIM:194380 | |
Generalized Juvenile Polyposis/Juvenile Polyposis Coli | Anemic pallor, Growth delay | ORPHA:329971 | |
Aregenerative Anemia | Pallor | ORPHA:101096 | |
3-Hydroxy-3-Methylglutaric Aciduria | Pallor | ORPHA:20 | |
Prolactinoma | Delayed puberty, Pallor | ORPHA:2965 | |
Panhypophysitis | Pallor | ORPHA:95513 | |
Incontinentia Pigmenti | Short stature, Erythema, Pallor | OMIM:308300 | |
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency | Pallor | OMIM:300908 | |
Sheehan Syndrome | Dry skin, Pallor | ORPHA:91355 | |
Pituitary Apoplexy | Pallor | ORPHA:95613 | |
Hereditary Pheochromocytoma-Paraganglioma | Pallor | ORPHA:29072 | |
Diamond-Blackfan Anemia 1 | Short stature, Spina bifida occulta, Intrauterine growth retardation, Pallor | OMIM:105650 | |
Fumarase Deficiency | Pallor | OMIM:606812 | |
Systemic Mastocytosis With Associated Hematologic Neoplasm | Pallor | ORPHA:98849 | |
Refractory Anemia With Excess Blasts | Anemic pallor | ORPHA:86839 | |
Fanconi Anemia, Complementation Group C | Short stature, Intrauterine growth retardation, Anemic pallor | OMIM:227645 | |
Methylmalonic Aciduria And Homocystinuria, Cblc Type | Pallor | OMIM:277400 | |
Alternating Hemiplegia Of Childhood | Pallor | ORPHA:2131 | |
Pearson Marrow-Pancreas Syndrome | Erythema, Pallor | OMIM:557000 | |
Esophageal Atresia | Growth delay, Pallor | ORPHA:1199 | |
Fanconi Anemia, Complementation Group E | Short stature, Anemic pallor | OMIM:600901 | |
Degcags Syndrome | Intrauterine growth retardation, Pallor, Patent ductus arteriosus | OMIM:619488 | |
Fanconi Anemia, Complementation Group A | Short stature, Anemic pallor | OMIM:227650 | |
Fanconi Anemia, Complementation Group D2 | Short stature, Anemic pallor, Patent ductus arteriosus | OMIM:227646 | |
Neuroblastoma | Anemic pallor | ORPHA:635 | |
Histiocytoid Cardiomyopathy | Pallor | ORPHA:137675 | |
Idiopathic Hypereosinophilic Syndrome | Pallor | ORPHA:3260 | |
Tsh-Secreting Pituitary Adenoma | Delayed puberty, Pallor | ORPHA:91347 | |
Diamond-Blackfan Anemia | Short stature, Growth delay, Pallor | ORPHA:124 | |
Autosomal Recessive Malignant Osteopetrosis | Growth delay, Pallor | ORPHA:667 | |
Infection-Related Hemolytic Uremic Syndrome | Pallor | ORPHA:544482 | |
Multiple Endocrine Neoplasia Type 2 | Pallor | ORPHA:653 | |
Von Hippel-Lindau Disease | Pallor | ORPHA:892 | |
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 3 | Pallor | OMIM:253280 | |
Goodpasture Syndrome | Pallor | OMIM:233450 | |
Congenital Total Pulmonary Venous Return Anomaly | Pallor, Patent ductus arteriosus | ORPHA:99125 |
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MGI Allele | Allele Type | Produced |
---|---|---|
Synatm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | ES Cells |
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