Gene: Rsf1

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Name
remodeling and spacing factor 1
MGI ID
MGI:2682305
Synonyms
XAP8 p325 Hbxap 4832420A03Rik C030033M12Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Rsf1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
decreased heart rate variability Rsf1tm1b(EUCOMM)Wtsi HET Early adult 5.08×10-08
abnormal embryo size Rsf1tm1b(EUCOMM)Wtsi HET E15.5 0.00
abnormal forebrain morphology Rsf1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo size Rsf1tm1b(EUCOMM)Wtsi HOM E15.5 0.00
abnormal QT variability Rsf1tm1b(EUCOMM)Wtsi HET Early adult 1.45×10-05
abnormal embryo size Rsf1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
increased circulating alkaline phosphatase level Rsf1tm1b(EUCOMM)Wtsi HET   Early adult 4.88×10-05
increased bone mineral density Rsf1tm1b(EUCOMM)Wtsi HET Early adult 5.52×10-13
abnormal liver size Rsf1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
decreased prepulse inhibition Rsf1tm1b(EUCOMM)Wtsi HET Early adult 1.73×10-05
abnormal eye morphology Rsf1tm1b(EUCOMM)Wtsi HET E12.5 0.00
abnormal placenta size Rsf1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
preweaning lethality, complete penetrance Rsf1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
improved glucose tolerance Rsf1tm1b(EUCOMM)Wtsi HET Early adult 2.34×10-06
abnormal embryo size Rsf1tm1b(EUCOMM)Wtsi HET E12.5 0.00
hypoactivity Rsf1tm1b(EUCOMM)Wtsi HET Early adult 1.44×10-05
cardiovascular system phenotype Rsf1tm1b(EUCOMM)Wtsi HET Early adult 1.14×10-08

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65)  (2/2) N/A
Brain 5  (6/506)  (2/5) N/A
Central nervous system ganglion 2  (1/74)  (2/2) N/A
Ear 5  (1/506)  (2/5) N/A
Embryo 5  (1/507)  (5/5) N/A
Eye 5  (1/506)  (2/5) N/A
Foot 5  (1/506)  (2/5) N/A
Forebrain 5  (1/506)  (2/5) N/A
Forelimb 5  (1/506)  (2/5) N/A
Gut 2  (1/60)  (2/2) N/A
Hand 5  (1/506)  (2/5) N/A
Head 5  (5/506)  (2/5) N/A
Heart 5  (1/506)  (2/5) N/A
Hindbrain 5  (6/506)  (2/5) N/A
Hindlimb 5  (1/506)  (2/5) N/A
Liver 5  (1/504)  (2/5) N/A
Lung 5  (1/504)  (2/5) N/A
Mandibular process 5  (1/506)  (2/5) N/A
Maxillary process 5  (1/506)  (2/5) N/A
Midbrain 5  (1/506)  (2/5) N/A
Nose 2  (1/76)  (2/2) N/A
Oral cavity 5  (1/504)  (2/5) N/A
Chorioallantoic placenta 2  (7/39)  (2/2) N/A
Skeleton 2  (1/76)  (2/2) N/A
Skin 5  (1/506)  (2/5) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 5  (1/506)  (2/5) N/A
Tail somite 5  (1/506)  (2/5) N/A
Trachea 2  (1/60)  (2/2) N/A
Urinary system 2  (1/60)  (2/2) N/A

 Associated Images

Immunophenotyping: Panel B FCS file(s)
3 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
Embryo LacZ: LacZ images wholemount
20 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Gross Pathology and Tissue Collection
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Immunophenotyping: Panel A FCS file(s)
3 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Histopathology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Rsf1tm1b(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rsf1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Rsf1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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