Ift172 | intraflagellar transport 172
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Mortality/aging Craniofacial Cardiovascular system
11 No significant impact
4 Not tested
Data collections
Gene metrics:14Significant phenotypes
7Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
abnormal allantois morphology | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal embryo development | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal digit morphology | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 3.78x10-5 | ||
embryonic growth retardation | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal embryo turning | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal heart morphology | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal neural tube closure | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
hemorrhage | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
edema | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
abnormal pericardium morphology | 1 supporting dataset | Ift172tm2b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * |
| | | | | | | | | |
adrenal gland | heterozygote | Wholemount images | 100% (2/2) | 0.7% (4/570) |
aorta | heterozygote | Wholemount images | n/a | 0.19% (1/533) |
bone | heterozygote | Wholemount images | 100% (2/2) | 0% (0/394) |
brain | heterozygote | Wholemount images | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | Wholemount images | 100% (2/2) | 0.22% (1/454) |
cerebellum | heterozygote | Wholemount images | 100% (2/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | Wholemount images | 100% (2/2) | 0.41% (2/491) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Ift172.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Ift172tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Ift172tm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Ift172tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |