Genes Phenotypes

Gene: Ift172

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Name
intraflagellar transport 172
MGI ID
MGI:2682064
Synonyms
avc1 4930553F24Rik wim
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (139) All data table (469)
Expression & images (113) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal pharyngeal arch morphology Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
embryonic growth retardation Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
preweaning lethality, complete penetrance Ift172tm2b(EUCOMM)Hmgu HOM Early adult 0.00
hemorrhage Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal embryo turning Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal pericardium morphology Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal heart morphology Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal allantois morphology Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Ift172tm2b(EUCOMM)Hmgu HOM E12.5 0.00
edema Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal embryo development Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal neural tube closure Ift172tm2b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal digit morphology Ift172tm2b(EUCOMM)Hmgu HET Early adult 6.22×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Wholemount images
Prostate gland 2 No  (12/584)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (1/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
endocrine system (1)
Trachea expression
Thyroid gland expression
Parathyroid gland expression
MA:0000441
MA:0000129
MA:0000128
exocrine system (1)
Lower Urinary Tract ambiguous
Vas Deferens ambiguous
Prostate gland ambiguous
MA:0002636
MA:0000413
MA:0000404
nervous system (2)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0002413
postnatal mouse (4)
Cerebral Cortex expression
Brain expression
Striatum expression
Hippocampus expression
Olfactory Lobe expression
MA:0000185
MA:0000168
MA:0000891
MA:0000191
MA:0002413
reproductive system (1)
Lower Urinary Tract ambiguous
Vas Deferens ambiguous
Prostate gland ambiguous
MA:0002636
MA:0000413
MA:0000404
respiratory system (1)
Trachea expression
Thyroid gland expression
Parathyroid gland expression
MA:0000441
MA:0000129
MA:0000128
trunk (2)
Lower Urinary Tract ambiguous
Vas Deferens ambiguous
Prostate gland ambiguous
MA:0002636
MA:0000413
MA:0000404
urinary system (1)
Lower Urinary Tract ambiguous
Vas Deferens ambiguous
Prostate gland ambiguous
MA:0002636
MA:0000413
MA:0000404
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57)  (2/2) N/A
Axial skeleton 2  (1/61)  (2/2) N/A
Brain 2  (6/504)  (2/2) N/A
Central nervous system ganglion 2  (1/70)  (2/2) N/A
Cranium 2  (1/61)  (2/2) N/A
Dorsal root ganglion 2  (1/57)  (2/2) N/A
Ear 2  (1/504)  (2/2) N/A
Embryo 2  (1/505)  (2/2) N/A
Outer ear 2  (1/66)  (2/2) N/A
Eye 2  (1/504)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/52)  (2/2) N/A
Foot 2  (1/504)  (2/2) N/A
Forearm 2  (1/297)  (2/2) N/A
Forebrain 2  (1/504)  (2/2) N/A
Forelimb 2  (1/504)  (2/2) N/A
Fronto-nasal process 2  (1/58)  (2/2) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 2  (1/503)  (2/2) N/A
Head 2  (5/504)  (2/2) N/A
Head mesenchyme 2  (1/57)  (2/2) N/A
Heart 2  (1/504)  (2/2) N/A
Heart ventricle 2  (1/57)  (2/2) N/A
Hindbrain 2  (6/504)  (2/2) N/A
Hindlimb 2  (1/503)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/61)  (2/2) N/A
Inner ear 2  (1/61)  (2/2) N/A
Intestine 2  (1/55)  (2/2) N/A
Liver 2  (1/504)  (2/2) N/A
Lower leg 2  (1/297)  (2/2) N/A
Lung 2  (1/500)  (2/2) N/A
Mandibular process 2  (1/504)  (2/2) N/A
Maxillary process 2  (1/504)  (2/2) N/A
Mesonephros of female 2  (1/52)  (1/2) N/A
Mesonephros of male 2  (1/52)  (1/2) N/A
Metanephros 2  (1/52)  (2/2) N/A
Midbrain 2  (1/504)  (2/2) N/A
Nasal septum 2  (1/57)  (2/2) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 2  (1/57)  (2/2) N/A
Oral cavity 2  (1/504)  (2/2) N/A
Outflow tract 2  (1/57)  (2/2) N/A
Pancreas 2  (1/52)  (2/2) N/A
Pericardium 2  (1/52)  (2/2) N/A
Pharynx 2  (1/52)  (2/2) N/A
Radius-ulna pre-cartilage condensation 2  (1/61)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/54)  (2/2) N/A
Skeleton 2  (1/70)  (2/2) N/A
Skin 2  (1/504)  (2/2) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Stomach 2  (1/52)  (2/2) N/A
Tail 2  (1/504)  (2/2) N/A
Tail somite 2  (1/504)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/52)  (2/2) N/A
Tongue 2  (1/52)  (2/2) N/A
Trachea 2  (1/56)  (2/2) N/A
Trunk mesenchyme 2  (1/57)  (2/2) N/A
Umbilical artery embryonic part 2  (1/57)  (2/2) N/A
Umbilical vein embryonic part 2  (1/57)  (2/2) N/A
Upper arm 2  (1/297)  (2/2) N/A
Upper leg 2  (1/297)  (2/2) N/A
Urinary system 2  (1/56)  (2/2) N/A
Vibrissa 2  (1/66)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ift172tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ift172tm2b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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