Gene Summary

Name:
tetratricopeptide repeat domain 37
Synonyms:
N/A

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ttc37em1(IMPC)Tcp HOM   Early adult 0.00
embryonic lethality prior to organogenesis Ttc37em1(IMPC)Tcp HOM   E9.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

10 Images

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

8 Images

X-ray

XRay Images Skull Lateral Orientation

8 Images

Human diseases caused by Ttc37 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Ttc37 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Syndromic Diarrhea
ORPHA:84064
Trichohepatoenteric Syndrome 1
OMIM:222470

The table below shows human diseases predicted to be associated to Ttc37 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Syndromic Diarrhea
ORPHA:84064
Trichohepatoenteric Syndrome 1
OMIM:222470

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Ttc37

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Ttc37.

No publications found that use IMPC mice or data for Ttc37.

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MGI Allele Allele Type Produced
Ttc37em1(IMPC)Tcp Exon Deletion Mice

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