Mib2 | mindbomb E3 ubiquitin protein ligase 2
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Nervous system Vision/eye Behavior/neurological
15 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased grip strength | 2 supporting datasets | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.49x10-6 | ||
abnormal retina morphology | 4 supporting datasets | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.03x10-5 | ||
decreased lean body mass | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 7.06x10-5 | ||
abnormal eye morphology | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.87x10-5 | ||
decreased blood urea nitrogen level | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.47x10-5 | ||
decreased prepulse inhibition | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.63x10-5 | ||
abnormal tail movements | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 7.06x10-7 | ||
decreased circulating amylase level | 1 supporting dataset | Mib2tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.47x10-6 |
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External links
No external links available for Mib2.
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Mib2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Mib2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Mib2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
Mib2tm44581(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |