Gene: Pyroxd1

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Name
pyridine nucleotide-disulphide oxidoreductase domain 1
MGI ID
MGI:2676395
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
tremors Pyroxd1tm1b(KOMP)Wtsi HET Early adult 1.39×10-07
decreased total retina thickness Pyroxd1tm1b(KOMP)Wtsi HET Early adult 9.50×10-07
abnormal stomach morphology Pyroxd1tm1b(KOMP)Wtsi HET Early adult 0.00
abnormal eye posterior chamber depth Pyroxd1tm1b(KOMP)Wtsi HET Early adult 3.02×10-06
preweaning lethality, complete penetrance Pyroxd1tm1b(KOMP)Wtsi HOM   Early adult 0.00
embryonic lethality prior to organogenesis Pyroxd1tm1b(KOMP)Wtsi HOM   E9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584)  (2/2) N/A
2 No  (1/584)  (2/2) N/A
2 No  (2/2) N/A
2 No  (4/584)  (2/2) N/A
2 No  (2/584)  (2/2) N/A
2 No N/A
2 No  (1/584)  (2/2) N/A
2 No  (11/370) N/A
2 No  (3/584)  (2/2) N/A
2 No  (2/584)  (2/2) N/A
2 No  (7/408) N/A
2 No N/A
2 No  (2/2) N/A
2 No  (2/584)  (2/2) N/A
2 No  (3/584)  (2/2) N/A
2 No  (2/584) N/A
2 No  (21/584)  (2/2) N/A
2 No  (10/584) N/A
2 No N/A
2 No  (1/584)  (2/2) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (2/584)  (2/2) N/A
2 No N/A
2 No  (1/584)  (1/2) N/A
2 No  (1/2) N/A
2 No  (5/584)  (2/2) N/A
2 No  (1/562)  (2/2) N/A
2 No  (2/584)  (2/2) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (12/584)  (1/2) N/A
2 No N/A
2 No  (1/584)  (2/2) N/A
2 No  (9/584) N/A
2 No  (3/584) N/A
2 No  (3/584) N/A
2 No  (12/584) N/A
2 No  (3/584)  (2/2) N/A
2 No  (6/584)  (1/2) N/A
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (3/584)  (2/2) N/A
2 No  (2/2) N/A
2 No  (1/2) N/A
2 No  (14/381)  (1/2) N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Atrium 2  (1/59)  (2/2) N/A
Axial skeleton 2  (1/63)  (2/2) N/A
Brain 2  (6/507)  (2/2) N/A
Central nervous system ganglion 2  (1/72)  (2/2) N/A
Cranium 2  (1/63)  (2/2) N/A
Dorsal root ganglion 2  (1/59)  (2/2) N/A
Ear 2  (1/507)  (2/2) N/A
Embryo 2  (1/508)  (2/2) N/A
External ear 2  (1/73)  (2/2) N/A
Eye 2  (1/507)  (2/2) N/A
Femur pre-cartilage condensation 2  (1/54)  (2/2) N/A
Footplate 2  (1/507)  (2/2) N/A
Forearm 2  (1/304)  (2/2) N/A
Forebrain 2  (1/507)  (2/2) N/A
Forelimb 2  (1/507)  (2/2) N/A
Fronto-nasal process 2  (1/60)  (2/2) N/A
Gut 2  (1/58)  (2/2) N/A
Handplate 2  (1/507)  (2/2) N/A
Head 2  (5/507)  (2/2) N/A
Head mesenchyme 2  (1/59)  (2/2) N/A
Heart 2  (1/507)  (2/2) N/A
Heart ventricle 2  (1/59)  (2/2) N/A
Hindbrain 2  (6/507)  (2/2) N/A
Hindlimb 2  (1/507)  (2/2) N/A
Humerus pre-cartilage condensation 2  (1/63)  (2/2) N/A
Inner ear 2  (1/63)  (2/2) N/A
Intestine 2  (1/57)  (2/2) N/A
Liver 2  (1/502)  (2/2) N/A
Lower leg 2  (1/304)  (2/2) N/A
Lung 2  (1/502)  (2/2) N/A
Mandibular process 2  (1/507)  (2/2) N/A
Maxillary process 2  (1/507)  (2/2) N/A
Mesonephros of female 2  (1/54)  (2/2) N/A
Mesonephros of male 2  (1/54)  (2/2) N/A
Metanephros 2  (1/54)  (2/2) N/A
Midbrain 2  (1/507)  (2/2) N/A
Nasal septum 2  (1/59)  (2/2) N/A
Nose 2  (1/77)  (2/2) N/A
Notochord 2  (1/59)  (2/2) N/A
Oral cavity 2  (1/502)  (2/2) N/A
Outflow tract 2  (1/59)  (2/2) N/A
Pancreas 2  (1/54)  (2/2) N/A
Pericardium 2  (1/54)  (2/2) N/A
Pharynx 2  (1/55)  (2/2) N/A
Radius-ulna pre cartilage condensation 2  (1/63)  (2/2) N/A
Rib pre-cartilage condensation 2  (1/56)  (2/2) N/A
Skeleton 2  (1/77)  (2/2) N/A
Skin 2  (1/507)  (2/2) N/A
Spinal cord 2  (1/71)  (2/2) N/A
Stomach 2  (1/54)  (2/2) N/A
Tail 2  (1/507)  (2/2) N/A
Tail somite group 2  (1/507)  (2/2) N/A
Thoracic vertebral cartilage condensation 2  (1/54)  (2/2) N/A
Tongue 2  (1/54)  (2/2) N/A
Trachea 2  (1/58)  (2/2) N/A
Trunk mesenchyme 2  (1/59)  (2/2) N/A
Umbilical artery embryonic part 2  (1/59)  (2/2) N/A
Umbilical vein embryonic part 2  (1/59)  (2/2) N/A
Upper arm 2  (1/304)  (2/2) N/A
Upper leg 2  (1/304)  (2/2) N/A
Urinary system 2  (1/58)  (2/2) N/A
Vibrissa 2  (1/73)  (2/2) N/A

 Associated Images

Eye Morphology: VIP of left eye
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: VIP of right fundus
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: VIP of right eye
11 Images
Eye Morphology: VIP of left fundus
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Histopathology
1 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pyroxd1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pyroxd1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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