Shank2 | SH3 and multiple ankyrin repeat domains 2

GeneMGI:2671987Synonyms: ProSAP1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity9 supporting datasetsShank2em2(IMPC)RbrchomozygoteEarly adult6.2x10-32 
increased thigmotaxis2 supporting datasetsShank2em2(IMPC)RbrchomozygoteEarly adult3.04x10-6 
abnormal behavior1 supporting datasetShank2em2(IMPC)RbrchomozygoteEarly adult3.04x10-6 
increased bone mineral content2 supporting datasetsShank2em2(IMPC)RbrchomozygoteEarly adult2.42x10-6 
decreased erythrocyte cell number1 supporting datasetShank2em2(IMPC)RbrchomozygoteEarly adult3.96x10-6 
limb grasping1 supporting datasetShank2em2(IMPC)RbrchomozygoteEarly adult2.52x10-6 
limb grasping1 supporting datasetShank2em2(IMPC)RbrchomozygoteLate adult6.75x10-9 
abnormal locomotor behavior1 supporting datasetShank2em2(IMPC)RbrchomozygoteLate adult1.98x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Shank2em1(IMPC)RbrcIndelmouse
Shank2em2(IMPC)RbrcExon Deletionmouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter