Gene: Agap1

Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
MGI ID
MGI:2653690
Synonyms
Centg2 Ggap1
View
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
persistence of hyaloid vascular system Agap1tm1a(EUCOMM)Wtsi HOM postnatal 6.23×10-15
fused cornea and lens Agap1tm1a(EUCOMM)Wtsi HOM postnatal 1.30×10-09
abnormal lens morphology Agap1tm1a(EUCOMM)Wtsi HOM postnatal 4.31×10-06
increased hematocrit Agap1tm1a(EUCOMM)Wtsi HOM postnatal 5.88×10-05
preweaning lethality, incomplete penetrance Agap1tm1a(EUCOMM)Wtsi HOM n/a 0.00
decreased caudal vertebrae number Agap1tm1a(EUCOMM)Wtsi HOM postnatal 3.04×10-05
increased erythrocyte cell number Agap1tm1a(EUCOMM)Wtsi HOM postnatal 5.27×10-05
abnormal cranium morphology Agap1tm1a(EUCOMM)Wtsi HOM postnatal 2.38×10-05
cataract Agap1tm1a(EUCOMM)Wtsi HOM postnatal 4.31×10-06
absent pinna reflex Agap1tm1a(EUCOMM)Wtsi HOM postnatal 2.44×10-05
increased circulating potassium level Agap1tm1a(EUCOMM)Wtsi HOM postnatal 3.57×10-05
abnormal cornea morphology Agap1tm1a(EUCOMM)Wtsi HOM postnatal 2.53×10-06
corneal opacity Agap1tm1a(EUCOMM)Wtsi HOM postnatal 7.73×10-09
decreased circulating insulin level Agap1tm1a(EUCOMM)Wtsi HOM postnatal 2.23×10-06
abnormal iris morphology Agap1tm1a(EUCOMM)Wtsi HOM postnatal 4.71×10-06

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 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Slit Lamp
18 Images
Eye Morphology: Images Ophthalmoscopy
12 Images
X-ray: XRay Images Dorso Ventral
42 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Lateral Orientation
28 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
DSS Histology
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Agap1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors
Agap1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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