Gene: Agap1

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Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
MGI ID
MGI:2653690
Synonyms
Ggap1 Centg2
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
persistence of hyaloid vascular system Agap1tm1a(EUCOMM)Wtsi HOM Early adult 5.77×10-15
decreased caudal vertebrae number Agap1tm1a(EUCOMM)Wtsi HOM Early adult 2.31×10-05
increased erythrocyte cell number Agap1tm1a(EUCOMM)Wtsi HOM Early adult 3.40×10-05
fused cornea and lens Agap1tm1a(EUCOMM)Wtsi HOM Early adult 1.29×10-09
increased hematocrit Agap1tm1a(EUCOMM)Wtsi HOM Early adult 6.04×10-05
cataract Agap1tm1a(EUCOMM)Wtsi HOM Early adult 4.61×10-06
decreased circulating insulin level Agap1tm1a(EUCOMM)Wtsi HOM Early adult 1.90×10-06
preweaning lethality, incomplete penetrance Agap1tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal cranium morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 2.49×10-05
increased or absent threshold for auditory brainstem response Agap1tm1a(EUCOMM)Wtsi HOM Early adult 0.00
abnormal lens morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 4.61×10-06
abnormal cornea morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 2.05×10-06
corneal opacity Agap1tm1a(EUCOMM)Wtsi HOM Early adult 7.66×10-09
absent pinna reflex Agap1tm1a(EUCOMM)Wtsi HOM Early adult 8.45×10-08
long snout Agap1tm1a(EUCOMM)Wtsi HOM Early adult 3.16×10-05
increased circulating potassium level Agap1tm1a(EUCOMM)Wtsi HOM Early adult 4.81×10-05
abnormal snout morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 5.07×10-06
abnormal skin coloration Agap1tm1a(EUCOMM)Wtsi HOM Early adult 1.61×10-05
abnormal iris morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 4.89×10-06
abnormal tooth morphology Agap1tm1a(EUCOMM)Wtsi HOM Early adult 9.48×10-05

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 Expression

Expression data not available

 Associated Images

DSS Histology
8 Images
Eye Morphology: Images Ophthalmoscopy
12 Images
Eye Morphology: Images Slit Lamp
18 Images
X-ray: XRay Images Whole Body Dorso Ventral
42 Images
X-ray: XRay Images Whole Body Lateral Orientation
28 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
Legacy Phenotype Associated Images

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View all 7 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Agap1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors
Agap1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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