Mapk15 | mitogen-activated protein kinase 15
GeneMGI:2652894
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Hematopoietic system Behavior/neurological
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
decreased fasting circulating glucose level | 1 supporting dataset | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.91x10-5 | ||
abnormal coat/hair pigmentation | 1 supporting dataset | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Late adult | 1.58x10-6 | ||
increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Early adult | 8.33x10-6 | ||
hyperactivity | 2 supporting datasets | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Late adult | 3.75x10-7 | ||
decreased locomotor activity | 1 supporting dataset | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.34x10-6 | ||
abnormal startle reflex | 1 supporting dataset | Mapk15tm1b(EUCOMM)Hmgu | homozygote | Late adult | 3.31x10-6 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Mapk15.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Mapk15tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Mapk15tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Mapk15tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |