Lrrc8a | leucine rich repeat containing 8A VRAC subunit A
Physiological systems
15 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Vision/eye Respiratory system Mortality/aging Craniofacial
8 No significant impact
9 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
Human diseases caused by Lrrc8a mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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