Adgrb2 | adhesion G protein-coupled receptor B2

GeneMGI:2451244Synonyms: Bai2

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Nervous system Behavior/neurological

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

hyperactivity6 supporting datasetsAdgrb2tm1b(KOMP)MbphomozygoteEarly adult6.01x10-10 
decreased prepulse inhibition1 supporting datasetAdgrb2tm1b(KOMP)MbphomozygoteEarly adult4.75x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoteSection images
100% (2/2)0.7% (4/570)
aortaheterozygoten/an/a0.19% (1/533)
brainheterozygoteSection images
100% (2/2)0.86% (5/579)
brainstemheterozygoteSection images
100% (2/2)0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/2)0% (0/588)
cartilage tissueheterozygoten/a0% (0/2)0.22% (1/454)
cerebellumheterozygoteSection images
100% (2/2)0.56% (3/532)
cerebral cortexheterozygoteSection images
100% (2/2)0.41% (2/491)
epididymisheterozygoteSection images
100% (1/1)87.5% (21/24)
esophagusheterozygoten/a0% (0/2)1.67% (7/419)
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Histopathology

IMPC related publications

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Adgrb2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Adgrb2tm42012(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
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