Gene: Tspoap1 MGI:2450877

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Gene Summary

Name:
TSPO associated protein 1
Synonyms:
peripheral,  Bzrap1

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Tspoap1em1(IMPC)H HOM Late adult 2.55×10-05
decreased prepulse inhibition Tspoap1em1(IMPC)H HOM Early adult 2.12×10-05
increased circulating alkaline phosphatase level Tspoap1em1(IMPC)H HOM Late adult 5.66×10-08

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Lateral Orientation

9 Images

X-ray

XRay Images Whole Body Dorso Ventral

9 Images

Human diseases caused by Tspoap1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Tspoap1 by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Tspoap1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tspoap1.

No publications found that use IMPC mice or data for Tspoap1.

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MGI Allele Allele Type Produced
Tspoap1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tspoap1em2(IMPC)H Indel causing a Frameshift Mutation Mice
Tspoap1em1(IMPC)H Indel causing a Frameshift Mutation Mice
Tspoap1tm65(L1L2_gt0) Targeting vectors

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