Gars1 | glycyl-tRNA synthetase 1
Physiological systems
22 / 24 physiological systems tested
14 Significantly impacted by the knock-out
Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Digestive/alimentary Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Vision/eye Behavior/neurological Skeleton Mortality/aging
8 No significant impact
2 Not tested
Data collections
Gene metrics:13Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased exploration in new environment | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | 1.46x10-5 | ||
abnormal seminal vesicle morphology | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Late adult | N/A * | ||
abnormal skin morphology | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
enlarged urinary bladder | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Late adult | N/A * | ||
small spleen | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
increased circulating triglyceride level | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | 8.66x10-5 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Gars1em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Gars1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
abnormal sternum morphology | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
abnormal stomach morphology | 1 supporting dataset | Gars1em1(IMPC)Tcp | heterozygote | Early adult | N/A * |
| | | | | | | | | |
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Gars1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Gars1em1(IMPC)Tcp | Exon Deletion | | mouse |
Gars1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Gars1tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |