Pip4p1 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1

GeneMGI:2448501Synonyms: Tmem55b

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Respiratory system Hematopoietic system Behavior/neurological

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased pulmonary respiratory rate1 supporting datasetPip4p1em1(IMPC)CcpczhomozygoteEarly adult2.83x10-5 
increased CD4-negative, CD25-positive NK T cell number1 supporting datasetPip4p1em1(IMPC)CcpczhomozygoteEarly adult9.12x10-5 
hyperactivity1 supporting datasetPip4p1em1(IMPC)CcpczhomozygoteEarly adult9.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Pip4p1em1(IMPC)CcpczIndelmouse
Pip4p1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Pip4p1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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