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Gene: Yeats2 MGI:2447762

Gene Summary

Name:

YEATS domain containing 2

Synonyms:

N/A

Order Alleles

IMPC Data Collections

Body Weight Measurements
No Embryo Imaging Data
Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype	Allele	Zyg	Life Stage	P Value
hyperactivity	Yeats2^em1(IMPC)J	HET	Early adult	3.59×10^-05
preweaning lethality, complete penetrance	Yeats2^em1(IMPC)J	HOM	Early adult	0.00
impaired righting response	Yeats2^em1(IMPC)J	HET	Late adult	9.92×10^-07
limb grasping	Yeats2^em1(IMPC)J	HET	Late adult	3.13×10^-07
abnormal coat/hair pigmentation	Yeats2^em1(IMPC)J	HET	Late adult	3.56×10^-07
embryonic lethality prior to organogenesis	Yeats2^em1(IMPC)J	HOM	E9.5	0.00

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lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Yeats2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Yeats2 (2 diseases)
Human diseases predicted to be associated with Yeats2 (215 diseases)

The table below shows human diseases associated to Yeats2 by orthology or direct annotation.

Disease	Similarity of phenotypes	Matching phenotypes	Source
Epilepsy, Familial Adult Myoclonic, 4		Tremor	OMIM:615127
Benign Adult Familial Myoclonic Epilepsy		Hand tremor	ORPHA:86814

The table below shows human diseases predicted to be associated to Yeats2 by phenotypic similarity.

Disease	Matching phenotypes	Source
Mental Retardation, Autosomal Recessive 54	Hyperactivity	OMIM:617028
Schizophrenia 15	Hyperactivity	OMIM:613950
Attention Deficit-Hyperactivity Disorder	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:143465
22q13 deletion syndrome (Phelan-Mcdermid syndrome)	Hyperactivity	DECIPHER:20
Mental Retardation, Autosomal Recessive 2	Attention deficit hyperactivity disorder	OMIM:607417
Potocki-Lupski syndrome (17p11.2 duplication syndrome)	Hyperactivity	DECIPHER:19
Mental Retardation, Autosomal Dominant 45	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:617600
Intellectual Developmental Disorder, X-Linked, Syndromic, Houge Type	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:301008
Autism, Susceptibility To, 20	Attention deficit hyperactivity disorder	OMIM:618830
Mental Retardation, Autosomal Recessive 3	Hyperactivity	OMIM:608443
Occipital Hair, White Lock Of	White hair, Abnormal hair morphology	OMIM:310900
Tremor Of Intention, Ataxia, And Lipofuscinosis	Ataxia, Premature graying of hair, Intention tremor	OMIM:190200
Griscelli Syndrome, Type 3	Silver-gray hair, Large clumps of pigment irregularly distributed along hair shaft, White eyelashes	OMIM:609227
Immunodeficiency 8	Hyperactivity	OMIM:615401
Microcephaly 25, Primary, Autosomal Recessive	Attention deficit hyperactivity disorder	OMIM:618351
Graying Of Hair, Precocious	Premature graying of hair	OMIM:139100
Cerebellar Ataxia And Albinism	Head tremor, Albinism, Ataxia	OMIM:258300
Loose Anagen Hair Syndrome	Loose anagen hair, Sparse hair, Fair hair	OMIM:600628
Epilepsy, Focal, With Speech Disorder And With Or Without Impaired Intellectual Development	Attention deficit hyperactivity disorder	OMIM:245570
Developmental And Epileptic Encephalopathy 43	Ataxia, Hyperactivity	OMIM:617113
Albinism, Oculocutaneous, Type Iii	Albinism, Partial albinism, Red hair	OMIM:203290
Mental Retardation, X-Linked 77	Hyperactivity	OMIM:300454
Tietz Syndrome	Abnormality of skin pigmentation, Hypopigmentation of hair, White eyebrow, Hypopigmentation of th...	ORPHA:42665
Griscelli Syndrome, Type 1	Silver-gray hair, Melanin pigment aggregation in hair shafts, Hypopigmentation of the skin, Accum...	OMIM:214450
Intellectual Developmental Disorder, X-Linked 109	Hyperactivity	OMIM:309548
Uncombable Hair Syndrome	Trichodysplasia, Abnormal hair morphology, White hair, Coarse hair, Patchy alopecia, Woolly hair	ORPHA:1410
Griscelli Syndrome Type 3	Iris hypopigmentation, Hypopigmentation of hair, Partial albinism	ORPHA:79478
Intellectual Developmental Disorder, Autosomal Dominant 50, With Behavioral Abnormalities	Attention deficit hyperactivity disorder	OMIM:617787
Mental Retardation, Autosomal Dominant 52	Hyperactivity	OMIM:617796
Dilution, Pigmentary	Iris hypopigmentation, Hypopigmentation of hair, Hypopigmentation of the skin	OMIM:126070
Waardenburg Syndrome, Type 2B	White forelock, Heterochromia iridis, Premature graying of hair	OMIM:600193
Mental Retardation, Autosomal Dominant 33	Hyperactivity	OMIM:616311
Urocanase Deficiency	Tremor, Blue irides, Ataxia, Fair hair	OMIM:276880
Intellectual Developmental Disorder, X-Linked 72	Hyperactivity	OMIM:300271
Alpha-Aminoadipic And Alpha-Ketoadipic Aciduria	Attention deficit hyperactivity disorder	OMIM:204750
Mental Retardation, Autosomal Recessive 37	Hyperactivity	OMIM:615493
Albinism, Oculocutaneous, Type Ib	Hypopigmentation of hair, Albinism, Hypopigmentation of the skin	OMIM:606952
Sotos Syndrome 3	Hyperactivity	OMIM:617169
Spastic Tetraplegia, Thin Corpus Callosum, And Progressive Microcephaly	Inability to walk, Hyperactivity	OMIM:616657
Intellectual Developmental Disorder, X-Linked 101	Hyperactivity	OMIM:300928
Woolly Hair	Hypopigmentation of hair, Slow-growing hair, Sparse lateral eyebrow, Brittle hair, Abnormality of...	ORPHA:170
Sensorineural Hearing Loss-Early Graying-Essential Tremor Syndrome	Tremor, Heterochromia iridis, Premature graying of hair	ORPHA:66633
Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome	Hyperactivity	ORPHA:356996
Intellectual Disability-Expressive Aphasia-Facial Dysmorphism Syndrome	Hyperactivity	ORPHA:436151
Ermine Phenotype	Vitiligo, Albinism, White eyebrow, White hair, White eyelashes, Spotty hyperpigmentation	OMIM:227010
Albinism, Oculocutaneous, Type Iv	Hypopigmentation of hair, Albinism, Blue irides	OMIM:606574
Piebald Trait With Neurologic Defects	Absent pigmentation of the ventral chest, Ataxia, White forelock	OMIM:172850
Language Delay And Attention Deficit-Hyperactivity Disorder/Cognitive Impairment With Or Without Cardiac Arrhythmia	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:617182
Hypotrichosis 8	Nail pits, Sparse hair, Dry hair, Ridged nail, Coarse hair, Sparse axillary hair, Fair hair, Spar...	OMIM:278150
Primary Immunodeficiency Syndrome Due To Lamtor2 Deficiency	Hypopigmentation of hair, Partial albinism	ORPHA:90023
Hermansky-Pudlak Syndrome 3	Hypopigmentation of hair, Hypopigmentation of the skin	OMIM:614072
Piebald Trait-Neurologic Defects Syndrome	Hypopigmentation of hair, Abnormal eyebrow morphology, Irregular hyperpigmentation, Heterochromia...	ORPHA:2885
Neuroectodermal Melanolysosomal Disease	Tremor, Hypopigmentation of hair, Premature graying of hair, Ataxia, Generalized hyperpigmentatio...	ORPHA:33445
Waardenburg Syndrome, Type 4B	Heterochromia iridis, Premature graying of hair, White eyebrow, White eyelashes, White forelock, ...	OMIM:613265
Griscelli Syndrome, Type 2	Silver-gray hair, Melanin pigment aggregation in hair shafts, Hypopigmentation of the skin, Accum...	OMIM:607624
Elejalde Disease	Melanin pigment aggregation in hair shafts, Silver-gray hair, Ataxia, Accumulation of melanosomes...	OMIM:256710
Neurodevelopmental Disorder With Epilepsy And Hypoplasia Of The Corpus Callosum	Inability to walk, Gait disturbance, Dysmetria, Hyperactivity	OMIM:618090
Smith-Magenis syndrome	Hyperactivity	DECIPHER:8
White Forelock With Malformations	Poliosis, White forelock	OMIM:277740
Microcephaly, Seizures, And Developmental Delay	Ataxia, Hyperactivity	OMIM:613402
Waardenburg Syndrome, Type 2A	Albinism, Heterochromia iridis, Premature graying of hair, White eyebrow, Synophrys, White eyelas...	OMIM:193510
Oculocerebral Syndrome With Hypopigmentation	Silver-gray hair, Hypopigmentation of the skin, Athetosis	OMIM:257800
Waardenburg Syndrome, Type 4A	Heterochromia iridis, Premature graying of hair, White eyebrow, Ataxia, White eyelashes, White fo...	OMIM:277580
Intellectual Developmental Disorder, X-Linked 107	Hyperactivity	OMIM:301013
Insulin-Like Growth Factor I Deficiency	Hyperactivity	OMIM:608747
Oculocutaneous Albinism, Type Viii	Hypopigmentation of hair, Iris transillumination defect, Hypopigmentation of the skin	OMIM:619165
Waardenburg Syndrome Type 2	Hypopigmentation of hair, Heterochromia iridis, Premature graying of hair, White forelock, Hypopi...	ORPHA:895
Oculocutaneous Albinism Type 3	Iris hypopigmentation, Freckling, Generalized hypopigmentation of hair, White eyebrow, Red hair, ...	ORPHA:79433
Congenital Heart Defect-Round Face-Developmental Delay Syndrome	Generalized hyperpigmentation, Hypopigmentation of hair	ORPHA:1355
Albinism, Oculocutaneous, Type Ii	Hypopigmentation of hair, Albinism, Freckles in sun-exposed areas, Red hair, Blue irides, Hypopig...	OMIM:203200
Hyperphenylalaninemia, Mild, Non-Bh4-Deficient	Dystonia, Bradykinesia, Oculogyric crisis, Attention deficit hyperactivity disorder, Broad-based ...	OMIM:617384
Piebaldism	Hypopigmentation of hair, Heterochromia iridis, White eyebrow, Synophrys, Ataxia, White eyelashes...	ORPHA:2884
Osteoporosis-Oculocutaneous Hypopigmentation Syndrome	Hypopigmentation of hair, Albinism, Hypopigmentation of the skin	ORPHA:2786
8p23.1 deletion syndrome	Hyperactivity	DECIPHER:39
Aminoacylase 1 Deficiency	Hyperactivity	OMIM:609924
Griscelli Syndrome Type 1	Iris hypopigmentation, Premature graying of hair, White hair, Ataxia, Partial albinism	ORPHA:79476
Juvenile Huntington Disease	Dystonia, Gait ataxia, Ataxia, Bradykinesia, Progressive cerebellar ataxia, Hyperactivity, Broad-...	ORPHA:248111
Encephalopathy, Progressive, With Or Without Lipodystrophy	Dystonia, Ataxia, Hyperactivity	OMIM:615924
Yemenite Deaf-Blind Hypopigmentation Syndrome	Patchy hypo- and hyperpigmentation, Numerous pigmented freckles, White forelock	OMIM:601706
Thyroid Hormone Resistance, Generalized, Autosomal Dominant	Attention deficit hyperactivity disorder	OMIM:188570
Hyperprolinemia, Type I	Ataxia, Hyperactivity	OMIM:239500
X-Linked Intellectual Disability, Stocco Dos Santos Type	Hyperactivity	ORPHA:85288
Waardenburg-Shah Syndrome	Abnormality of retinal pigmentation, Abnormal eyebrow morphology, Hypopigmentation of hair, White...	ORPHA:897
Microcephaly 2, Primary, Autosomal Recessive, With Or Without Cortical Malformations	Hyperactivity	OMIM:604317
Glycine Encephalopathy	Lethargy, Hyperactivity	OMIM:605899
Oculocutaneous Albinism Type 4	Iris hypopigmentation, Hypopigmentation of hair, Albinism, Abnormality of retinal pigmentation, W...	ORPHA:79435
Mannosidosis, Beta A, Lysosomal	Hyperactivity	OMIM:248510
Piebald Trait	Heterochromia iridis, Partial albinism, White forelock, Absent pigmentation of the ventral chest,...	OMIM:172800
Intellectual Developmental Disorder, X-Linked 104	Ataxia, Hyperactivity	OMIM:300983
Vogt-Koyanagi-Harada Disease	Vitiligo, Abnormal eyebrow morphology, Premature graying of hair, Abnormal eyelash morphology, Po...	ORPHA:3437
Dihydropyrimidine Dehydrogenase Deficiency	Lethargy, Hyperactivity	OMIM:274270
Waardenburg Syndrome Type 1	Hypopigmentation of hair, Heterochromia iridis, Premature graying of hair, White eyebrow, Abnorma...	ORPHA:894
Aniridia-Ptosis-Intellectual Disability-Familial Obesity Syndrome	Hypopigmentation of hair, Alopecia	ORPHA:1067
Histidinemia	Hyperactivity	ORPHA:2157
Oculocutaneous Albinism	Iris hypopigmentation, Hypopigmentation of hair, Generalized hypopigmentation of hair, White eyeb...	ORPHA:55
Ataxia-Telangiectasia	Tremor, Hypopigmentation of hair, Premature graying of hair, Ataxia, Multiple cafe-au-lait spots	ORPHA:100
Fraxe Intellectual Disability	Hyperactivity	ORPHA:100973
Angelman Syndrome Due To Imprinting Defect In 15Q11-Q13	Iris hypopigmentation, Hypopigmentation of hair, Hypopigmentation of the skin, Ataxia	ORPHA:411515
Hyperlysinemia, Type I	Hyperactivity	OMIM:238700
Mental Retardation, Autosomal Recessive 39	Hyperactivity	OMIM:615541
Ectodermal Dysplasia, Hidrotic, Christianson-Fourie Type	Short eyelashes, Sparse axillary hair, Absent eyebrow, Fair hair, Sparse scalp hair, Sparse pubic...	OMIM:601375
Mental Retardation, Autosomal Dominant 43	Hyperactivity	OMIM:616977
Dystonia, Dopa-Responsive, Due To Sepiapterin Reductase Deficiency	Dystonia, Ataxia, Hyperactivity	OMIM:612716
Intellectual Developmental Disorder, X-Linked, Syndromic, Stocco Dos Santos Type	Hyperactivity	OMIM:300434
Xq25 Microduplication Syndrome	Hyperactivity	ORPHA:521258
Prader-Willi Syndrome Due To Imprinting Mutation	Iris hypopigmentation, Hypopigmentation of hair, Hypopigmentation of the skin	ORPHA:177910
Xq25 Duplication Syndrome	Hyperactivity	OMIM:300979
Chromosome 3Q29 Deletion Syndrome	Gait ataxia, Hyperactivity	OMIM:609425
Coffin-Siris Syndrome 8	Hyperactivity	OMIM:618362
Oculocutaneous Albinism Type 2	Iris hypopigmentation, Abnormality of retinal pigmentation, Freckling, Hypopigmentation of hair, ...	ORPHA:79432
Lennox-Gastaut Syndrome	Falls, Hyperactivity	ORPHA:2382
Alazami-Yuan Syndrome	Hyperactivity	OMIM:617126
Optic Atrophy 11	Dysmetria, Ataxia, Hyperactivity	OMIM:617302
Classic Phenylketonuria	Tremor, Hypopigmentation of the skin, Hypopigmentation of hair	ORPHA:79254
Oculocutaneous Albinism Type 1B	Iris hypopigmentation, Freckling, Albinism, Abnormality of retinal pigmentation, Hypopigmentation...	ORPHA:79434
Acquired Hypertrichosis Lanuginosa	Generalized hirsutism, Hypopigmentation of hair, Abnormal eyebrow morphology, Fine hair	ORPHA:2221
Oculocutaneous Albinism Type 1	Iris hypopigmentation, Generalized hypopigmentation of hair, White eyebrow, White eyelashes, Gene...	ORPHA:352731
Guanidinoacetate Methyltransferase Deficiency	Dystonia, Athetosis, Ataxia, Hyperactivity	ORPHA:382
Intellectual Developmental Disorder, X-Linked 30	Hyperactivity	OMIM:300558
Phenylketonuria	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:261600
Intellectual Developmental Disorder, Autosomal Recessive 71	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:618504
Obesity, Early-Onset, With Adrenal Insufficiency And Red Hair	Red hair	OMIM:609734
Gand Syndrome	Hyperactivity	OMIM:615074
Obesity Due To Prohormone Convertase I Deficiency	Hypopigmentation of the skin, Red hair	ORPHA:71528
Obesity Due To Pro-Opiomelanocortin Deficiency	Hypopigmentation of the skin, Red hair	ORPHA:71526
Ermine Phenotype	Iris hypopigmentation, Hypopigmentation of hair, Irregular hyperpigmentation, Ocular albinism, Hy...	ORPHA:999
Oculocutaneous Albinism Type 1A	Iris hypopigmentation, Freckling, Albinism, Hypopigmentation of hair, Ocular albinism, Hypopigmen...	ORPHA:79431
Neurodevelopmental Disorder With Movement Abnormalities, Abnormal Gait, And Autistic Features	Unsteady gait, Broad-based gait, Hyperactivity	OMIM:617865
Carney Complex, Type 1	Freckling, Red hair, Hirsutism, Profuse pigmented skin lesions, Multiple lentigines	OMIM:160980
Cln5 Disease	Dysdiadochokinesis, Inability to walk, Truncal ataxia, Ataxia, Unsteady gait, Dysmetria, Hyperact...	ORPHA:228360
Clark-Baraitser Syndrome	Hyperactivity	OMIM:617752
Albinism, Oculocutaneous, Type Ia	Hypopigmentation of hair, Albinism, Absent skin pigmentation, White hair, Ocular albinism, Blue i...	OMIM:203100
Landau-Kleffner Syndrome	Steppage gait, Gait ataxia, Attention deficit hyperactivity disorder, Hyperactivity	ORPHA:98818
Griscelli Syndrome Type 2	Iris hypopigmentation, Hypopigmentation of hair, Partial albinism, Premature graying of hair	ORPHA:79477
Mental Retardation, Autosomal Recessive 38	Unsteady gait, Hyperactivity	OMIM:615516
Mental Retardation, Autosomal Recessive 13	Hyperactivity	OMIM:613192
X-Linked Intellectual Disability-Hypotonia-Movement Disorder Syndrome	Broad-based gait, Hyperactivity	ORPHA:457260
Neurodevelopmental Disorder With Behavioral Abnormalities, Absent Speech, And Hypotonia	Inability to walk, Hyperactivity	OMIM:618718
Childhood-Onset Motor And Cognitive Regression Syndrome With Extrapyramidal Movement Disorder	Inability to walk, Dystonia, Gait ataxia, Hyperactivity	ORPHA:500180
X-Linked Intellectual Disability-Psychosis-Macroorchidism Syndrome	Broad-based gait, Shuffling gait, Hyperactivity	ORPHA:3077
Succinic Semialdehyde Dehydrogenase Deficiency	Ataxia, Hyperactivity	OMIM:271980
Acrodysostosis 2 With Or Without Hormone Resistance	Red hair, Blue irides, Fair hair	OMIM:614613
Waardenburg Syndrome	Abnormality of skin pigmentation, Hypopigmentation of hair, Abnormal eyebrow morphology, Heteroch...	ORPHA:3440
Severe Neurodegenerative Syndrome With Lipodystrophy	Limb dystonia, Gait ataxia, Ataxia, Hyperactivity	ORPHA:363400
Chromosome 15Q25 Deletion Syndrome	Attention deficit hyperactivity disorder, Hyperactivity	OMIM:614294
Waardenburg Syndrome, Type 4C	Heterochromia iridis, Premature graying of hair, White eyebrow, White eyelashes, White forelock, ...	OMIM:613266
Rasmussen Subacute Encephalitis	Inability to walk, Hemidystonia, Attention deficit hyperactivity disorder, Hyperactivity	ORPHA:1929
Mitochondrial Complex Iii Deficiency, Nuclear Type 7	Hyperactivity	OMIM:615824
Hoyeraal-Hreidarsson Syndrome	Generalized hypopigmentation of hair, Premature graying of hair, Ataxia, Sparse scalp hair, Gener...	ORPHA:3322
Intellectual Disability-Obesity-Prognathism-Eye And Skin Anomalies Syndrome	Hyperactivity	ORPHA:397973
Chediak-Higashi Syndrome	Iris hypopigmentation, Tremor, Hypopigmentation of hair, Giant melanosomes in melanocytes, Silver...	OMIM:214500
Muenke Syndrome	Hypopigmentation of hair, Hypermelanotic macule, Hypopigmented skin patches	ORPHA:53271
Graves Disease, Susceptibility To, 1	Hyperactivity	OMIM:275000
Angelman Syndrome Due To Maternal 15Q11Q13 Deletion	Iris hypopigmentation, Tremor, Hypopigmentation of hair, Ataxia, Hypopigmentation of the skin	ORPHA:98794
Deaf Blind Hypopigmentation Syndrome, Yemenite Type	Iris hypopigmentation, Freckling, Hypopigmentation of hair, Hyperpigmentation of the skin, Multip...	ORPHA:3214
Intellectual Developmental Disorder, X-Linked, Syndromic, Snijders Blok Type	Broad-based gait, Hyperactivity	OMIM:300958
Intellectual Developmental Disorder, X-Linked 21	Hyperactivity	OMIM:300143
Fragile X Syndrome	Hyperactivity	OMIM:300624
Angelman Syndrome Due To A Point Mutation	Iris hypopigmentation, Hypopigmentation of hair, Hypopigmentation of the skin, Ataxia	ORPHA:411511
X-Linked Intellectual Disability-Acromegaly-Hyperactivity Syndrome	Hyperactivity	ORPHA:85327
X-Linked Creatine Transporter Deficiency	Dystonia, Athetosis, Ataxia, Hyperactivity	ORPHA:52503
Myoclonic-Astatic Epilepsy	Unsteady gait, Attention deficit hyperactivity disorder, Ataxia, Hyperactivity	ORPHA:1942
Hypomagnesemia, Seizures, And Mental Retardation 2	Hyperactivity	OMIM:618314
Female Restricted Epilepsy With Intellectual Disability	Hyperactivity	ORPHA:101039
Mental Retardation, Autosomal Dominant 7	Gait disturbance, Ataxia, Hyperactivity	OMIM:614104
Squalene Synthase Deficiency	Abnormality of hair pigmentation	OMIM:618156
Severe Motor And Intellectual Disabilities-Sensorineural Deafness-Dystonia Syndrome	Hyperactivity	ORPHA:369939
Hyperthyroidism, Nonautoimmune	Hyperactivity	OMIM:609152
Infantile Neuroaxonal Dystrophy	Dystonia, Gait disturbance, Ataxia, Unsteady gait, Hyperactivity	ORPHA:35069
Angelman Syndrome Due To Paternal Uniparental Disomy Of Chromosome 15	Iris hypopigmentation, Hypopigmentation of hair, Hypopigmentation of the skin	ORPHA:98795
Neurodevelopmental Disorder With Or Without Autism Or Seizures	Hyperactivity	OMIM:619239
Hypohidrotic Ectodermal Dysplasia	Irregular hyperpigmentation, Generalized hypopigmentation of hair, Abnormality of the nail, Abnor...	ORPHA:238468
Lamb-Shaffer Syndrome	Ataxia, Hyperactivity	ORPHA:530983
Neurodegeneration With Brain Iron Accumulation 2B	Dysdiadochokinesis, Dystonia, Gait ataxia, Bradykinesia, Dysmetria, Hyperactivity	OMIM:610217
X-Linked Adrenoleukodystrophy	Gait disturbance, Attention deficit hyperactivity disorder, Hyperactivity	ORPHA:43
Brittle Cornea Syndrome 1	Red hair	OMIM:229200
Pitt-Hopkins-Like Syndrome 1	Ataxia, Hyperactivity	OMIM:610042
Mucopolysaccharidosis, Type Iiia	Hyperactivity	OMIM:252900
Oculocerebral Hypopigmentation Syndrome, Cross Type	Iris hypopigmentation, Hypopigmentation of hair, Ocular albinism, Ataxia, Athetosis	ORPHA:2719
Epilepsy, Familial Adult Myoclonic, 4	Tremor	OMIM:615127
Peripheral Demyelinating Neuropathy-Central Dysmyelinating Leukodystrophy-Waardenburg Syndrome-Hirschsprung Disease	Hypopigmentation of hair, Abnormal eyebrow morphology, Heterochromia iridis, Premature graying of...	ORPHA:163746
X-Linked Cerebral Adrenoleukodystrophy	Inability to walk, Difficulty walking, Gait disturbance, Ataxia, Dysmetria, Hyperactivity	ORPHA:139396
Adenylosuccinase Deficiency	Inability to walk, Gait ataxia, Hyperactivity	OMIM:103050
Chédiak-Higashi Syndrome	Iris hypopigmentation, Tremor, Abnormality of retinal pigmentation, Hypopigmentation of hair, Lar...	ORPHA:167
Intellectual Developmental Disorder, X-Linked, Syndromic, Billuart Type	Gait ataxia, Hyperactivity	OMIM:300486
Spastic Paraplegia 29, Autosomal Dominant	Hyperactivity	OMIM:609727
47,Xyy Syndrome	Attention deficit hyperactivity disorder, Hyperactivity	ORPHA:8
Hermansky-Pudlak Syndrome	Iris hypopigmentation, Hypopigmentation of hair, Melanocytic nevus, Ocular albinism, Long eyelash...	ORPHA:79430
Koolen-De Vries Syndrome	Hypopigmentation of hair, Abnormality of hair texture	ORPHA:96169
Prader-Willi Syndrome	Iris hypopigmentation, Hypopigmentation of hair, Impaired pain sensation, Generalized hypopigment...	OMIM:176270
Sim1-Related Prader-Willi-Like Syndrome	Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation of the skin	ORPHA:398079
Vici Syndrome	Hypopigmentation of hair, Albinism, Ocular albinism, Hypopigmentation of the skin	OMIM:242840
Purine Nucleoside Phosphorylase Deficiency	Ataxia, Hyperactivity	ORPHA:760
Syndromic Diarrhea	Hypopigmentation of hair, Uncombable hair, Brittle hair, Cafe-au-lait spot, Woolly hair, Trichorr...	ORPHA:84064
Magel2-Related Prader-Willi-Like Syndrome	Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation of the skin	ORPHA:398069
Familial Gestational Hyperthyroidism	Hyperactivity	ORPHA:99819
Brittle Cornea Syndrome	Abnormality of hair pigmentation	ORPHA:90354
Prader-Willi Syndrome Due To Maternal Uniparental Disomy Of Chromosome 15	Iris hypopigmentation, Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation...	ORPHA:98754
Prader-Willi Syndrome Due To Paternal 15Q11Q13 Deletion	Iris hypopigmentation, Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation...	ORPHA:98793
Neurodegeneration With Brain Iron Accumulation 1	Dystonia, Akinesia, Gait disturbance, Blepharospasm, Ataxia, Bradykinesia, Hyperactivity	OMIM:234200
Autosomal Recessive Faciodigitogenital Syndrome	Widow's peak, Coarse hair, Hypopigmentation of hair, Dry hair	ORPHA:1974
Prader-Willi Syndrome Due To Paternal Deletion Of 15Q11Q13 Type 2	Iris hypopigmentation, Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation...	ORPHA:177904
Prader-Willi Syndrome Due To Paternal Deletion Of 15Q11Q13 Type 1	Iris hypopigmentation, Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation...	ORPHA:177901
Familial Hyperthyroidism Due To Mutations In Tsh Receptor	Hyperactivity	ORPHA:424
Menkes Disease	Chorea, Hypopigmentation of hair, Woolly hair, Sparse hair	ORPHA:565
Prader-Willi-Like Syndrome	Iris hypopigmentation, Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation...	ORPHA:398073
Prader-Willi Syndrome	Hypopigmentation of hair, Impaired temperature sensation, Hypopigmentation of the skin	ORPHA:739
Cerebellar Ataxia, Nonprogressive, With Mental Retardation	Dysmetria, Unsteady gait, Ataxia, Hyperactivity	OMIM:614756
Prader-Willi Syndrome Due To Translocation	Iris hypopigmentation, Hypopigmentation of hair, Hyperpigmentation of the skin, Hypopigmentation ...	ORPHA:177907
Argininemia	Spastic gait, Hyperactivity	OMIM:207800
Benign Adult Familial Myoclonic Epilepsy	Hand tremor	ORPHA:86814
Carney Complex	Red hair, Hirsutism, Cafe-au-lait spot, Profuse pigmented skin lesions, Hypermelanotic macule, Mu...	ORPHA:1359
Acrodysostosis With Multiple Hormone Resistance	Red hair, Blue irides, Fair hair	ORPHA:280651
Cystinosis, Nephropathic	Hypopigmentation of hair, Retinal pigment epithelial mottling, Hypopigmentation of the skin, Pigm...	OMIM:219800
Smith-Lemli-Opitz Syndrome	Hypopigmentation of hair, Abnormal eyelash morphology	ORPHA:818

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Yeats2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Yeats2.

No publications found that use IMPC mice or data for Yeats2.

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MGI Allele	Allele Type	Produced
Yeats2^em1(IMPC)J	Exon Deletion	Mice
Yeats2^{tm303588(L1L2_Bact_P)}		Targeting vectors

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