Gene: Klk14

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating triglyceride level Klk14tm1.1(KOMP)Vlcg HOM Early adult 2.56×10-06
decreased circulating glucose level Klk14tm1.1(KOMP)Vlcg HOM Early adult 2.48×10-05
abnormal leukocyte cell number Klk14tm1.1(KOMP)Vlcg HOM Early adult 6.63×10-05
abnormal circulating triglyceride level Klk14tm1.1(KOMP)Vlcg HOM Early adult 1.08×10-08
convulsive seizures Klk14tm1.1(KOMP)Vlcg HET Early adult 4.36×10-05
abnormal circulating free fatty acids level Klk14tm1.1(KOMP)Vlcg HOM Early adult 5.51×10-06
abnormal circulating glucose level Klk14tm1.1(KOMP)Vlcg HOM Early adult 6.04×10-07

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 6 No  (3/589)  Section images
Aorta 6 No  (1/589)  Section images
Blood 4 No N/A
Bone 6 No  Section images
Bone marrow 6 No N/A
Brain 6 No  (3/589)  Section images
Brainstem 6 No  (2/589)  Section images
Brown adipose tissue 6 No  Section images
Cartilage tissue 6 No  Section images
Cecum 4 No  (12/379)  (1/4)  Section images
Cerebellum 6 No  (3/589)  Section images
Cerebral cortex 6 No  (2/589)  Section images
Chest bone 4 No  Section images
Colon 4 No  (12/127)  Section images
Cranium 4 No  Section images
Diaphragm 4 No  Section images
Duodenum 4 No  (2/127)  Section images
Epididymis 6 No  (18/134) N/A
Esophagus 6 No  (7/415)  (4/6)  Section images
Eye 6 No  Section images
Gall bladder 4 No  Section images
Gonadal fat pad 4 No N/A
Harderian gland 4 No  Section images
Heart 6 No  (1/589)  Section images
Hindlimb 4 No  (2/4)  Section images
Hippocampus 6 No  (3/589)  Section images
Hypothalamus 6 No  (2/589)  Section images
Ileum 4 No  (14/127)  Section images
Jejunum 4 No  (6/127)  Section images
Kidney 6 No  (20/589)  Section images
Large intestine 6 No  (10/589)  Section images
Liver 6 No  Section images
Lower urinary tract 6 No  (1/589)  Section images
Lung 6 No  (1/589)  (2/6)  Section images
Lymph node 6 No  Section images
Main olfactory bulb 4 No N/A
Mammary gland 6 No  Section images
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 No N/A
Midbrain 6 No N/A
Olfactory lobe 6 No  (2/589)  Section images
Oral epithelium 4 No  (2/4)  Section images
Ovary 6 No  (1/589)  Section images
Oviduct 6 No  Section images
Pancreas 6 No  (5/589)  Section images
Parathyroid gland 4 No  Section images
Parotid gland 4 No N/A
Penis 4 No  (1/4)  Section images
Peripheral nervous system 6 No  (1/589)  Section images
Peyer's patch 6 No  Section images
Pituitary gland 6 No  (1/589)  Section images
Prostate gland 6 No  (12/589)  (1/6)  Section images
Quadriceps 6 No  Section images
Sciatic nerve 4 No N/A
Skeletal muscle 6 No  Section images
Skin 6 No  (4/6)  Section images
Small intestine 6 No  (9/589)  Section images
Spinal cord 6 No  (2/589)  Section images
Spleen 6 No  (2/589)  Section images
Stomach 6 No  (13/589)  (4/6)  Section images
Stomach pyloric region 4 No N/A
Striatum 6 No  (3/589)  Section images
Sublingual gland 4 No N/A
Submandibular gland 6 No  (2/132)  Section images
Testis 6 No  (5/589)  (1/6)  Section images
Thalamus 6 No N/A
Thymus 6 No  (3/6)  Section images
Thyroid gland 6 No  (16/589)  Section images
Tongue 4 No  (5/127)  (4/4)  Section images
Trachea 6 No  (2/589)  Section images
Trigeminal V nerve 4 No N/A
Urinary bladder 6 No  Section images
Uterus 6 No  Section images
Vagina 4 No  (1/4)  Section images
Vas deferens 4 No  (15/388) N/A
Vascular system 6 No  Section images
Vesicular gland 6 No N/A
White adipose tissue 6 No  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/61) N/A
Axial skeleton 2  (1/65) Image Only N/A
Brain 4  (6/506) N/A
Central nervous system ganglion 2  (1/74) Image Only N/A
Cranium 2  (1/65) Image Only N/A
Dorsal root ganglion 4  (1/61) N/A
Ear 4  (1/506) N/A
Embryo 4  (1/507)  (4/5)  Wholemount images
Outer ear 2  (1/70) Image Only N/A
Eye 4  (1/506) N/A
Femur pre-cartilage condensation 2  (1/56) N/A
Foot 4  (1/506) N/A
Forearm 2  (1/301) Image Only N/A
Forebrain 4  (1/506) N/A
Forelimb 4  (1/506) N/A
Fronto-nasal process 4  (1/62) N/A
Gut 4  (1/60)  (2/4) N/A
Hand 4  (1/505) N/A
Head 4  (5/506) N/A
Head mesenchyme 2  (1/61) N/A
Heart 4  (1/506)  (2/5) N/A
Heart ventricle 2  (1/61) N/A
Hindbrain 4  (6/506) N/A
Hindlimb 4  (1/505) N/A
Humerus pre-cartilage condensation 2  (1/65) Image Only N/A
Inner ear 2  (1/65) Image Only N/A
Intestine 2  (1/59) N/A
Liver 4  (1/506) N/A
Lower leg 2  (1/301) Image Only N/A
Lung 4  (1/502) N/A
Mandibular process 4  (1/506) N/A
Maxillary process 4  (1/506) N/A
Meckel's cartilage 2 N/A
Mesonephros of female 2  (1/56) N/A
Mesonephros of male 2  (1/56) N/A
Metanephros 2  (1/56) N/A
Midbrain 4  (1/506) N/A
Nasal septum 2  (1/61) N/A
Nose 4  (1/74) N/A
Notochord 2  (1/61) N/A
Oral cavity 4  (1/506) N/A
Outflow tract 2  (1/61) N/A
Pancreas 2  (1/56) N/A
Pericardium 2  (1/56) N/A
Pharynx 2  (1/56) N/A
Radius-ulna pre-cartilage condensation 2  (1/65) Image Only N/A
Rib pre-cartilage condensation 2  (1/58) N/A
Skeleton 2  (1/74) Image Only N/A
Skin 4  (1/506) N/A
Spinal cord 4  (1/73) N/A
Stomach 2  (1/56) N/A
Tail 4  (1/506) N/A
Tail somite 4  (1/506) N/A
Thoracic vertebral cartilage condensation 2  (1/56) N/A
Tongue 2  (1/56) N/A
Trachea 2  (1/60) N/A
Trunk mesenchyme 2  (1/61) N/A
Umbilical artery embryonic part 2  (1/61) N/A
Umbilical vein embryonic part 2  (1/61) N/A
Upper arm 2  (1/301) Image Only N/A
Upper leg 2  (1/301) Image Only N/A
Urinary system 2  (1/60) N/A
Vibrissa 2  (1/70) Image Only N/A

 Associated Images

Adult LacZ: LacZ Images Section
131 Images
Embryo LacZ: LacZ images wholemount
20 Images
X-ray: XRay Images Whole Body Lateral Orientation
19 Images
X-ray: XRay Images Skull Lateral Orientation
19 Images
Eye Morphology: Images Ophthalmoscopy
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
19 Images
Sleep Wake: Wake state (bmp file)
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
19 Images
X-ray: XRay Images Forepaw
18 Images
Electroretinography 2: Rod and cone PDF
7 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Klk14tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Klk14tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Klk14tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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