Gene: Slc24a4

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Name
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
MGI ID
MGI:2447362
Synonyms
NCKX4 A930002M03Rik
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Slc24a4tm1b(KOMP)Wtsi HOM Early adult 0.00
decreased fasting circulating glucose level Slc24a4tm1b(KOMP)Wtsi HOM Early adult 5.01×10-05
increased circulating HDL cholesterol level Slc24a4tm1b(KOMP)Wtsi HET Early adult 1.20×10-05
abnormal circulating alkaline phosphatase level Slc24a4tm1b(KOMP)Wtsi HOM Early adult 3.94×10-08
abnormal fasting circulating glucose level Slc24a4tm1b(KOMP)Wtsi HOM Early adult 4.22×10-05
increased circulating cholesterol level Slc24a4tm1b(KOMP)Wtsi HET Early adult 8.56×10-06
enlarged thymus Slc24a4tm1b(KOMP)Wtsi HET Early adult 0.00
decreased red blood cell distribution width Slc24a4tm1b(KOMP)Wtsi HET Early adult 6.02×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Bone 2 No N/A
Brain 2 No  (3/589)  (2/2)  Wholemount images
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (1/589)  (2/2)  Wholemount images
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589) N/A
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/589) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/589) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589)  (2/2)  Wholemount images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (1/2)  Wholemount images
Striatum 2 No  (3/589) N/A
Testis 2 No  (5/589)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (2/4) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/505) N/A
Head 2  (5/506)  (2/4) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/505) N/A
Liver 2  (1/506) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Oral cavity 2  (1/506) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
19 Images
X-ray: XRay Images Whole Body Dorso Ventral
19 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
18 Images
Adult LacZ: LacZ Images Wholemount
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc24a4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Slc24a4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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