Sik3 | SIK family kinase 3
Physiological systems
19 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Vision/eye Obsolete decreased cd4-positive, alpha beta t cell number Reproductive system Integument Limbs/digits/tail Immune system Homeostasis/metabolism Adipose tissue Skeleton Hematopoietic system Pigmentation Craniofacial Growth/size/body region
6 No significant impact
6 Not tested
Data collections
Gene metrics:77Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Sik3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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