Sik3 | SIK family kinase 3
Physiological systems
19 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Pigmentation Integument Adipose tissue Obsolete decreased cd4-positive, alpha beta t cell number Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Skeleton Craniofacial
6 No significant impact
6 Not tested
Data collections
Gene metrics:77Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Sik3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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