Gene: Setd1a

Log in to follow

Name
SET domain containing 1A
MGI ID
MGI:2446244
Synonyms
KMT2F
Viability
N/A
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating HDL cholesterol level Setd1atm1a(EUCOMM)Wtsi HET postnatal 4.19×10-08
decreased circulating cholesterol level Setd1atm1a(EUCOMM)Wtsi HET postnatal 1.30×10-08
increased bone mineral density Setd1atm1a(EUCOMM)Wtsi HET postnatal 1.42×10-08
increased CD8-positive, alpha-beta T cell number Setd1atm1a(EUCOMM)Wtsi HET postnatal 7.42×10-06
decreased circulating alkaline phosphatase level Setd1atm1a(EUCOMM)Wtsi HET postnatal 1.25×10-06
decreased B cell number Setd1atm1a(EUCOMM)Wtsi HET postnatal 1.41×10-08
decreased circulating LDL cholesterol level Setd1atm1a(EUCOMM)Wtsi HET postnatal 3.47×10-08
decreased leukocyte cell number Setd1atm1a(EUCOMM)Wtsi HET postnatal 3.51×10-15
decreased circulating alanine transaminase level Setd1atm1a(EUCOMM)Wtsi HET postnatal 8.01×10-05
decreased total body fat amount Setd1atm1a(EUCOMM)Wtsi HET postnatal 3.84×10-08

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Lymph node - MPATH diagnostic term Lymphoid neoplasms Setd1atm1a(EUCOMM)Wtsi HET postnatal
Lymph node - hyperplasia Setd1atm1a(EUCOMM)Wtsi HET postnatal
Lymph node - neoplasm Setd1atm1a(EUCOMM)Wtsi HET postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Setd1atm1(IMPC)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice
Setd1atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Setd1atm39777(L1L2_gt0_Del_LacZ) Targeting vectors
Setd1atm39777(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Setd1atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Setd1atm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Setd1atm1.2(IMPC)Wtsi Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette) Mice

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter