Gene: Setd1a

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Name
SET domain containing 1A
MGI ID
MGI:2446244
Synonyms
KMT2F
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased lean body mass Setd1atm1a(EUCOMM)Wtsi HET Early adult 2.31×10-21
decreased circulating alkaline phosphatase level Setd1atm1a(EUCOMM)Wtsi HET Early adult 2.62×10-05
decreased total body fat amount Setd1atm1a(EUCOMM)Wtsi HET Early adult 4.65×10-23
increased bone mineral density Setd1atm1a(EUCOMM)Wtsi HET Early adult 7.85×10-12
increased bone mineral content Setd1atm1a(EUCOMM)Wtsi HET Early adult 6.13×10-08
decreased circulating HDL cholesterol level Setd1atm1a(EUCOMM)Wtsi HET Early adult 1.85×10-07
decreased circulating LDL cholesterol level Setd1atm1a(EUCOMM)Wtsi HET Early adult 1.94×10-11
decreased circulating cholesterol level Setd1atm1a(EUCOMM)Wtsi HET Early adult 2.04×10-14
decreased leukocyte cell number Setd1atm1a(EUCOMM)Wtsi HET Early adult 1.15×10-24

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 Expression

Expression data not available

 Associated Images

Histopathology
2 Images
Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Lymph node - hyperplasia Setd1atm1a(EUCOMM)Wtsi HET Early adult
Lymph node - MPATH diagnostic term lymphoid neoplasms Setd1atm1a(EUCOMM)Wtsi HET Early adult
Lymph node - neoplasm Setd1atm1a(EUCOMM)Wtsi HET Early adult

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MGI Allele Allele Type Produced
Setd1atm39777(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Setd1atm39777(L1L2_gt0_Del_LacZ) Targeting vectors
Setd1atm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Setd1atm1.2(IMPC)Wtsi Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette) Mice
Setd1atm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Setd1atm1(IMPC)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice
Setd1atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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