Setd1a | SET domain containing 1A
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Skeleton
13 No significant impact
5 Not tested
Data collections
Gene metrics:14Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased lean body mass | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.39x10-14 | ||
increased blood urea nitrogen level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.08x10-17 | ||
decreased leukocyte cell number | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.97x10-13 | ||
decreased circulating LDL cholesterol level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 8.49x10-7 | ||
increased bone mineral density | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 6.42x10-12 | ||
increased bone mineral content | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.83x10-8 | ||
increased circulating creatinine level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.43x10-33 | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.22x10-8 | ||
increased circulating fructosamine level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.15x10-5 | ||
decreased circulating cholesterol level | 1 supporting dataset | Setd1atm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.39x10-8 |
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This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Setd1a.
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Setd1atm1(IMPC)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Setd1atm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
Setd1atm1.2(IMPC)Wtsi | Reporter-tagged deletion allele (post Flp, with no reporter and selection cassette) | | mouse |
Setd1atm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Setd1atm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Setd1atm39777(L1L2_gt0_Del_LacZ) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Setd1atm39777(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |