Gene: Rfx6

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hydrometra Rfx6tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal uterus morphology Rfx6tm1.1(KOMP)Vlcg HET Early adult 0.00
impaired glucose tolerance Rfx6tm1.1(KOMP)Vlcg HET   Early adult 1.45×10-05
increased basophil cell number Rfx6tm1.1(KOMP)Vlcg HET   Early adult 8.67×10-05
preweaning lethality, complete penetrance Rfx6tm1.1(KOMP)Vlcg HOM   Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (4/583) N/A
Aorta 4 No  (1/583) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 4 No  (4/583) N/A
Brainstem 4 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 4 No  (1/583) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 4 No  (3/583) N/A
Cerebral cortex 4 No  (2/583) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 4 No  (7/407) N/A
Eye 4 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 4 No  (2/583) N/A
Hindlimb 2 No N/A
Hippocampus 4 No  (3/583) N/A
Hypothalamus 4 No  (2/583) N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 4 No  (21/583)  (2/4)  Section images
Large intestine 4 No  (10/583)  (1/4) N/A
Liver 4 No N/A
Lower urinary tract 4 No  (1/583) N/A
Lung 4 No  (2/583) N/A
Lymph node 4 No  (1/583) N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 4 No  (2/583) N/A
Ovary 4 No  (1/583) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 4 No  (2/583) N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/583) N/A
Prostate gland 4 No  (12/583)  (1/4)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 4 No N/A
Skin 4 No  (1/583) N/A
Small intestine 4 No  (9/583)  (1/4) N/A
Spinal cord 4 No  (3/583) N/A
Spleen 4 No  (3/583) N/A
Stomach 4 No  (13/583)  (1/4)  Section images
Stomach pyloric region 2 No N/A
Striatum 4 No  (3/583) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/130) N/A
Testis 4 No  (6/583) N/A
Thymus 4 No  (1/583) N/A
Thyroid gland 4 No  (17/583) N/A
Tongue 2 No  (5/127) N/A
Trachea 4 No  (3/583) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 4 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/382) N/A
Vascular system 4 No N/A
Vesicular gland 2 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
4  (6/505) N/A
2  (1/73) N/A
4  (1/505) N/A
4  (1/506)  (2/4) N/A
4  (1/505) N/A
4  (1/505) N/A
4  (1/505) N/A
4  (1/505) N/A
2  (1/59)  (2/2) N/A
4  (1/505) N/A
4  (5/505) N/A
4  (1/505) N/A
4  (6/505) N/A
4  (1/505) N/A
4  (1/503) N/A
4  (1/503) N/A
4  (1/505) N/A
4  (1/505) N/A
4  (1/505) N/A
2  (1/75) N/A
4  (1/503) N/A
2  (7/39)  (2/2) N/A
2  (1/75) N/A
4  (1/505) N/A
2  (1/72) N/A
4  (1/505) N/A
4  (1/505) N/A
2  (1/59) N/A
2  (1/59) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
Adult LacZ: LacZ Images Section
7 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rfx6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Rfx6tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Rfx6tm43096(L1L2_gt0) Targeting vectors
Rfx6tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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