Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
preweaning lethality, complete penetrance | Rfx6tm1.1(KOMP)Vlcg | HOM | n/a | 0.00 | ||
impaired glucose tolerance | Rfx6tm1.1(KOMP)Vlcg | HET | postnatal | 7.63×10-06 |
Gene: Rfx6
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Expression
IMPC lacZ Expression Data
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 4 | No | (2/584) | N/A | |
Aorta | 4 | No | N/A | ||
Blood | 2 | No | N/A | ||
Bone marrow | 2 | No | N/A | ||
Brain | 4 | No | N/A | ||
Brainstem | 4 | No | N/A | ||
Brown adipose tissue | 2 | No | N/A | ||
Cartilage tissue | 4 | No | N/A | ||
Cecum | 2 | No | (12/383) | N/A | |
Cerebellum | 4 | No | N/A | ||
Cerebral cortex | 4 | No | N/A | ||
Chest bone | 2 | No | N/A | ||
Colon | 2 | No | (12/127) | N/A | |
Diaphragm | 2 | No | N/A | ||
Duodenum | 2 | No | (2/127) | N/A | |
Epididymis | 2 | No | (18/134) | (1/2) | N/A |
Esophagus | 4 | No | (7/415) | N/A | |
Eye | 4 | No | N/A | ||
Gall bladder | 2 | No | N/A | ||
Gonadal fat pad | 2 | No | N/A | ||
Harderian gland | 2 | No | N/A | ||
Heart | 4 | No | N/A | ||
Hindlimb | 2 | No | N/A | ||
Hippocampus | 4 | No | N/A | ||
Hypothalamus | 4 | No | N/A | ||
Ileum | 2 | No | (14/127) | (1/2) | N/A |
Jejunum | 2 | No | (6/127) | N/A | |
Kidney | 4 | No | (18/584) | (2/4) | Section images |
Large intestine | 4 | No | (10/584) | (1/4) | N/A |
Liver | 4 | No | N/A | ||
Lower urinary tract | 4 | No | N/A | ||
Lung | 4 | No | N/A | ||
Lymph node | 4 | No | N/A | ||
Mammary gland | 4 | No | N/A | ||
Mesenteric adipose tissue | 2 | No | N/A | ||
Mesenteric lymph node | 2 | No | N/A | ||
Midbrain | 2 | No | N/A | ||
Olfactory lobe | 4 | No | N/A | ||
Ovary | 4 | No | (1/584) | N/A | |
Oviduct | 4 | No | N/A | ||
Pancreas | 4 | No | (5/584) | N/A | |
Parathyroid gland | 2 | No | N/A | ||
Parotid gland | 2 | No | N/A | ||
Penis | 2 | No | N/A | ||
Peripheral nervous system | 4 | No | N/A | ||
Peyer's patch | 4 | No | N/A | ||
Pituitary gland | 4 | No | N/A | ||
Prostate gland | 4 | No | (12/584) | (1/4) | Section images |
Quadriceps | 2 | No | N/A | ||
Sciatic nerve | 2 | No | N/A | ||
Skeletal muscle | 4 | No | N/A | ||
Skin | 4 | No | N/A | ||
Small intestine | 4 | No | (9/584) | (1/4) | N/A |
Spinal cord | 4 | No | N/A | ||
Spleen | 4 | No | (2/584) | N/A | |
Stomach | 4 | No | (12/584) | (1/4) | N/A |
Stomach pyloric region | 2 | No | N/A | ||
Striatum | 4 | No | N/A | ||
Sublingual gland | 2 | No | N/A | ||
Submandibular gland | 2 | No | (2/132) | N/A | |
Testis | 4 | No | (2/584) | N/A | |
Thymus | 4 | No | N/A | ||
Thyroid gland | 4 | No | (15/584) | N/A | |
Tongue | 2 | No | (5/127) | N/A | |
Trachea | 4 | No | N/A | ||
Trigeminal V nerve | 2 | No | N/A | ||
Urinary bladder | 2 | No | N/A | ||
Uterus | 4 | No | N/A | ||
Vagina | 2 | No | N/A | ||
Vas deferens | 2 | No | (15/388) | N/A | |
Vascular system | 4 | No | N/A | ||
Vesicular gland | 2 | No | N/A | ||
White adipose tissue | 4 | No | N/A |
LacZ Wholemount Images
LacZ Section Images
Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
---|---|---|---|---|
Axial skeleton | 2 | (1/51) | N/A | |
Brain | 4 | (6/485) | N/A | |
Central nervous system ganglion | 2 | (1/51) | N/A | |
Ear | 4 | (1/485) | N/A | |
Embryo | 4 | (1/485) | (2/4) | N/A |
Eye | 4 | (1/485) | N/A | |
Foot | 4 | (1/485) | N/A | |
Forebrain | 4 | (1/485) | N/A | |
Forelimb | 4 | (1/485) | N/A | |
Gut | 2 | (1/50) | (2/2) | N/A |
Hand | 4 | (1/485) | N/A | |
Head | 4 | (5/485) | N/A | |
Heart | 4 | (1/485) | N/A | |
Hindbrain | 4 | (6/485) | N/A | |
Hindlimb | 4 | (1/485) | N/A | |
Liver | 4 | (1/485) | N/A | |
Lung | 4 | (1/485) | N/A | |
Mandibular process | 4 | (1/485) | N/A | |
Maxillary process | 4 | (1/485) | N/A | |
Midbrain | 4 | (1/485) | N/A | |
Nose | 2 | (1/51) | N/A | |
Oral cavity | 4 | (1/485) | N/A | |
2 | (7/25) | (2/2) | N/A | |
Skeleton | 2 | (1/51) | N/A | |
Skin | 4 | (1/485) | N/A | |
Spinal cord | 2 | (1/50) | N/A | |
Tail | 4 | (1/485) | N/A | |
Tail somite | 4 | (1/485) | N/A | |
Trachea | 2 | (1/50) | N/A | |
Urinary system | 2 | (1/50) | N/A |
Associated Images
Disease Models
Order Mouse and ES Cells
MGI Allele | Allele Type | Availability |
---|---|---|
Rfx6tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | Mice, Targeting vectors, ES Cells |
Rfx6tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | Mice, Tissue |
Rfx6tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Rfx6tm43096(L1L2_gt0) | Targeting vectors |
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