Gene: Rfx6

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Rfx6tm1.1(KOMP)Vlcg HOM n/a 0.00
impaired glucose tolerance Rfx6tm1.1(KOMP)Vlcg HET postnatal 7.63×10-06

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 4 No N/A
Brainstem 4 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 4 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 4 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 4 No N/A
Hindlimb 2 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 2 No  (14/127)  (1/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 4 No  (18/584)  (2/4)  Section images
Large intestine 4 No  (10/584)  (1/4) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584)  (1/4)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584)  (1/4) N/A
Spinal cord 4 No N/A
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (1/4) N/A
Stomach pyloric region 2 No N/A
Striatum 4 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 4 No  (2/584) N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 4 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 4 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 4 No N/A
Vesicular gland 2 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 4  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 4  (1/485) N/A
Embryo 4  (1/485)  (2/4) N/A
Eye 4  (1/485) N/A
Foot 4  (1/485) N/A
Forebrain 4  (1/485) N/A
Forelimb 4  (1/485) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 4  (1/485) N/A
Head 4  (5/485) N/A
Heart 4  (1/485) N/A
Hindbrain 4  (6/485) N/A
Hindlimb 4  (1/485) N/A
Liver 4  (1/485) N/A
Lung 4  (1/485) N/A
Mandibular process 4  (1/485) N/A
Maxillary process 4  (1/485) N/A
Midbrain 4  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 4  (1/485) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51) N/A
Skin 4  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 4  (1/485) N/A
Tail somite 4  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Section
2 Images
X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rfx6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Rfx6tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Rfx6tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Rfx6tm43096(L1L2_gt0) Targeting vectors

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