Gene: Klhl3

Name
kelch-like 3
MGI ID
MGI:2445185
Synonyms
7530408C15Rik EG627648
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased hemoglobin content Klhl3tm1b(KOMP)Wtsi HOM postnatal 1.12×10-06
increased circulating potassium level Klhl3tm1b(KOMP)Wtsi HOM postnatal 9.61×10-17

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
12 Images
X-ray: XRay Images Lateral Orientation
10 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Skeletal muscle - process of degenerative change Klhl3tm1b(KOMP)Wtsi HOM postnatal
Skin - process of degenerative change Klhl3tm1b(KOMP)Wtsi HOM postnatal

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Klhl3tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Klhl3tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Klhl3tm1a(KOMP)Mbp KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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