IMPC Data Collections
- Body Weight Measurements
- No Embryo Imaging Data
- Viability Data
The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
|Phenotype||System||Allele||Zyg||Sex||Life Stage||P Value|
|embryonic lethality prior to organogenesis||Exoc1em1(IMPC)Mbp||HOM||E9.5||0.00|
|increased exploration in new environment||Exoc1em1(IMPC)Mbp||HET||Early adult||9.02×10-05|
|preweaning lethality, complete penetrance||Exoc1em1(IMPC)Mbp||HOM||Early adult||0.00|
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases predicted to be associated to Exoc1 by phenotypic similarity.
|Monoamine Oxidase A Deficiency||
Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.
There is no histopathology data for Exoc1
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Exoc1.
There are 1 publication which use IMPC produced mice or data.
|Title||Journal||IMPC Allele||PubMed ID|
|Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.||Scientific reports (September 2015)||Exoc1tm1a(EUCOMM)Hmgu||PMC4562154|
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
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|MGI Allele||Allele Type||Produced|
|Exoc1tm1e(EUCOMM)Hmgu||Targeted, non-conditional allele||ES Cells|
|Exoc1tm1a(EUCOMM)Hmgu||KO first allele (reporter-tagged insertion with conditional potential)||Targeting vectors, ES Cells|
|Exoc1em1(IMPC)Mbp||Exon Deletion||Mice, Tissue|
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