Phldb2 | pleckstrin homology like domain, family B, member 2

GeneMGI:2444981Synonyms: C820004H04Rik, LL5b, +1 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Nervous system Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased basophil cell number2 supporting datasetsPhldb2em1(IMPC)HhomozygoteEarly adult8.74x10-9 
absent optic nerve1 supporting datasetPhldb2em1(IMPC)HhomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetPhldb2em1(IMPC)HhomozygoteEarly adult1.89x10-17 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Phldb2em1(IMPC)HIndelmouse
Phldb2em2(IMPC)HIndelmouse
Phldb2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Phldb2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Phldb2tm43128(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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