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Gene: Tecrl MGI:2444966

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Gene Summary

Name:
trans-2,3-enoyl-CoA reductase-like
Synonyms:
D330017N19Rik,  Srd5a2l2

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Tecrlem1(IMPC)J HOM Early adult 7.31×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Forepaw

8 Images

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X-ray

XRay Images Whole Body Lateral Orientation

8 Images

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X-ray

XRay Images Whole Body Dorso Ventral

8 Images

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X-ray

XRay Images Skull Dorso Ventral Orientation

8 Images

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X-ray

XRay Images Skull Lateral Orientation

8 Images

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Electroretinography 3

Fundus file

9 Images

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PDF thumbnail PDF
Electrocardiogram (ECG)

Waveform Image

15 Images

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PDF thumbnail PDF
Auditory Brain Stem Response

Click-evoked + 6 to 30kHz tone waveforms (pdf format)

7 Images

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Human diseases caused by Tecrl mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Tecrl by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Catecholaminergic Polymorphic Ventricular Tachycardia
ORPHA:3286
Ventricular Tachycardia, Catecholaminergic Polymorphic, 3
OMIM:614021

The table below shows human diseases predicted to be associated to Tecrl by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Catecholaminergic Polymorphic Ventricular Tachycardia
ORPHA:3286
Ventricular Tachycardia, Catecholaminergic Polymorphic, 3
OMIM:614021

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Tecrl

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Tecrl.

No publications found that use IMPC mice or data for Tecrl.

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All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Tecrltm1e(KOMP)Wtsi Targeted, non-conditional allele ES Cells
Tecrltm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Tecrlem1(IMPC)J Exon Deletion Mice
Tecrltm42923(L1L2_gt0) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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